Patents by Inventor Peter Senter

Peter Senter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED PYRROLOBENZODIAZAPINE CONJUGATES
    Publication number: 20180228916
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Application
    Filed: April 12, 2018
    Publication date: August 16, 2018
    Inventors: Philip Wilson Howard, Scott Jeffrey, Patrick Burke, Peter Senter
  • Pyrrolobenzodiazepines used to treat proliferative diseases
    Patent number: 9732084
    Abstract: Pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position on one monomer unit, and a C2-C3 double bond and either a conjugated double or triple bond at the C2 position or an alkyl group at the C2 position on the other monomer unit, and conjugates of these compounds.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: August 15, 2017
    Assignees: Medimmune Limited, Seattle Genetics Inc.
    Inventors: Philip Wilson Howard, Luke Masterson, Arnaud Tiberghien, Scott Jeffrey, Patrick Burke, Peter Senter
  • HYDROPHILIC ANTIBODY-DRUG CONJUGATES
    Publication number: 20170216391
    Abstract: Hydrophilic Linkers, Drug-Linker compounds, Drug-Ligand Conjugate compounds and Ligand-Linkers and methods of making and using the same are provided.
    Type: Application
    Filed: February 17, 2015
    Publication date: August 3, 2017
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Svetlana Doronina, Robert Lyon, Peter Senter
  • TARGETED PYRROLOBENZODIAZAPINE CONJUGATES
    Publication number: 20170143846
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Application
    Filed: February 1, 2017
    Publication date: May 25, 2017
    Inventors: Philip Wilson HOWARD, Scott JEFFREY, Patrick BURKE, Peter SENTER
  • Targeted pyrrolobenzodiazapine conjugates
    Patent number: 9592240
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: March 14, 2017
    Assignees: SEATTLE GENETICS INC., MEDIMMUNE LIMITED
    Inventors: Philip Wilson Howard, Scott Jeffrey, Patrick Burke, Peter Senter
  • METHODS OF INHIBITION OF PROTEIN FUCOSYLATION IN VIVO USING FUCOSE ANALOGS
    Publication number: 20170035790
    Abstract: The invention provides methods and compositions for the inhibition of fucosylation of proteins, including antibodies, in vivo by administration of a fucose analog.
    Type: Application
    Filed: October 21, 2016
    Publication date: February 9, 2017
    Applicant: Seattle Genetics, Inc.
    Inventors: Peter Senter, Stephen Alley, Dennis Benjamin
  • Methods of inhibition of protein fucosylation in vivo using fucose analogs
    Patent number: 9504702
    Abstract: The invention provides methods and compositions for the inhibition of fucosylation of proteins, including antibodies, in vivo by administration of a fucose analog.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: November 29, 2016
    Assignee: Seattle Genetics, Inc.
    Inventors: Peter Senter, Stephen Alley, Dennis Benjamin
  • Auristatin drug linker conjugates
    Patent number: 9463252
    Abstract: Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: October 11, 2016
    Assignee: Seattle Genetics, Inc.
    Inventors: Peter Senter, Svetlana Doronina, Timothy Bovee
  • TARGETED PYRROLOBENZODIAZAPINE CONJUGATES
    Publication number: 20160129013
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Application
    Filed: January 14, 2016
    Publication date: May 12, 2016
    Inventors: Philip Wilson HOWARD, Scott JEFFREY, Patrick BURKE, Peter SENTER
  • Targeted pyrrolobenzodiazapine conjugates
    Patent number: 9242013
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: January 26, 2016
    Assignees: SEATTLE GENETICS INC., MEDIMMUNE LIMITED
    Inventors: Philip Wilson Howard, Scott Jeffrey, Patrick Burke, Peter Senter
  • Pyrrolobenzodiazepines used to treat proliferative diseases
    Patent number: 8697688
    Abstract: Pyrrolobenzodiazepine dimers I having a C2-C3 double bond and an aryl group at the C2 position on one monomer unit, and a C2-C3 double bond and either a conjugated double or triple bond at the C2 position or an alkyl group at the C2 position on the other monomer unit, and conjugates of these compounds.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: April 15, 2014
    Assignees: Seattle Genetics Inc., Spirogen Sarl
    Inventors: Philip Wilson Howard, Luke Masterson, Arnaud Tiberghien, Scott Jeffrey, Patrick Burke, Peter Senter
  • PYRROLOBENZODIAZEPINES USED TO TREAT PROLIFERATIVE DISEASES
    Publication number: 20140066435
    Abstract: Pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position on one monomer unit, and a C2-C3 double bond and either a conjugated double or triple bond at the C2 position or an alkyl group at the C2 position on the other monomer unit, and conjugates of these compounds.
    Type: Application
    Filed: November 6, 2013
    Publication date: March 6, 2014
    Applicant: SPIROGEN SARL
    Inventors: Philip Wilson HOWARD, Luke MASTERSON, Arnaud TIBERGHIEN, Scott JEFFREY, Patrick BURKE, Peter SENTER
  • AURISTATIN DRUG LINKER CONJUGATES
    Publication number: 20140050746
    Abstract: Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.
    Type: Application
    Filed: October 23, 2013
    Publication date: February 20, 2014
    Applicant: Seattle Genetics, Inc.
    Inventors: Peter Senter, Svetlana Doronina, Timothy Bovee
  • Auristatin drug linker conjugates
    Patent number: 8609105
    Abstract: Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: December 17, 2013
    Assignee: Seattle Genetics, Inc.
    Inventors: Peter Senter, Svetlana Doronina, Timothy Bovee
  • METHODS OF INHIBITION OF PROTEIN FUCOSYLATION IN VIVO USING FUCOSE ANALOGS
    Publication number: 20130129784
    Abstract: The invention provides methods and compositions for the inhibition of fucosylation of proteins, including antibodies, in vivo by administration of a fucose analog.
    Type: Application
    Filed: August 5, 2011
    Publication date: May 23, 2013
    Applicant: Seattle Genetics, Inc.
    Inventors: Peter Senter, Stephen Alley, Dennis Benjamin
  • PYRROLOBENZODIAZEPINES USED TO TREAT PROLIFERATIVE DISEASES
    Publication number: 20130059800
    Abstract: Pyrrolobenzodiazepine dimers I having a C2-C3 double bond and an aryl group at the C2 position on one monomer unit, and a C2-C3 double bond and either a conjugated double or triple bond at the C2 position or an alkyl group at the C2 position on the other monomer unit, and conjugates of these compounds.
    Type: Application
    Filed: April 15, 2011
    Publication date: March 7, 2013
    Applicants: SEATTLE GENETICS INC., SPIROGEN DEVELOPMENTS SÀRL
    Inventors: Philip Wilson Howard, Luke Masterson, Arnaud Tiberghien, Scott Jeffrey, Patrick Burke, Peter Senter
  • TARGETED PYRROLOBENZODIAZAPINE CONJUGATES
    Publication number: 20130028919
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Application
    Filed: April 15, 2011
    Publication date: January 31, 2013
    Applicants: SPIROGEN DEVELOPMENTS SÀRL, SEATTLE GENETICS, INC.
    Inventors: Philip Wilson Howard, Scott Jeffrey, Patrick Burke, Peter Senter
  • Antibody drug conjugates (ADC) that bind to 24P4C12 proteins
    Patent number: 8309093
    Abstract: Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: November 13, 2012
    Assignee: Agensys, Inc.
    Inventors: Jean Gudas, Aya Jakobovits, Zili An, Robert Kendall Morrison, Karen Jane Meyrick Morrison, Xiao-chi Jia, Dennis Benjamin, Ruth Moser, Peter Senter
  • AURISTATIN DRUG LINKER CONJUGATES
    Publication number: 20110020343
    Abstract: Drug Linker compounds and Drug Linker Ligand conjugates are provided that have auristatins linked via the C-terminus. The conjugates show efficacy without the need for a self-immolative group to release the drug.
    Type: Application
    Filed: March 18, 2009
    Publication date: January 27, 2011
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Peter Senter, Svetlana Doronina, Timothy Bovee
  • ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 24P4C12 PROTEINS
    Publication number: 20100330107
    Abstract: Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
    Type: Application
    Filed: March 5, 2010
    Publication date: December 30, 2010
    Applicants: AGENSYS, INC., SEATTLE GENETICS
    Inventors: Jean Gudas, Aya Jakobovits, Zili An, Robert Kendall Morrison, Karen Jane Meyrick Morrison, Xiao-chi Jia, Dennis Benjamin, Ruth Moser, Peter Senter