Patents by Inventor Peter SHAHINIAN

Peter SHAHINIAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10973899
    Abstract: The invention provides, inter alia, improved replicons and vectors encoding them, where the replicons provide sustained expression of an encoded protein. These replicons comprise flavivirus replicases and heterologous protein coding sequences, wherein the heterologous protein coding sequences are flanked by separation sequences for improved efficacy. These nucleic acids provided by the invention, including self-replicating RNAs provided by the invention, are useful in methods of protein expression, such as for vaccines (e.g., for methods of immunization), as well as expression of therapeutic proteins, such as antibodies (e.g., for methods of treatment).
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: April 13, 2021
    Assignee: Novartis AG
    Inventors: Caitlin Jeanette Hagen, Dong Yu, Peter W. Mason, Peter Shahinian
  • Publication number: 20180036398
    Abstract: The invention provides, inter alia, improved replicons and vectors encoding them, where the replicons provide sustained expression of an encoded protein. These replicons comprise flavivirus replicases and heterologous protein coding sequences, wherein the heterologous protein coding sequences are flanked by separation sequences for improved efficacy. These nucleic acids provided by the invention, including self-replicating RNAs provided by the invention, are useful in methods of protein expression, such as for vaccines (e.g., for methods of immunization), as well as expression of therapeutic proteins, such as antibodies (e.g., for methods of treatment).
    Type: Application
    Filed: February 25, 2016
    Publication date: February 8, 2018
    Inventors: Caitlin Jeanette HAGEN, Dong YU, Peter W. MASON, Peter SHAHINIAN