Patents by Inventor Peter Sobolewski

Peter Sobolewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7439057
    Abstract: The present invention provides for an improved in vitro tissue assembly system and related methods that includes and uses a bioreactor, a porous mandrel disposed in the bioreactor, and components that provide for the circulation of culture media and cell suspensions within the bioreactor and through the porous mandrel. The circulation of the culture media and cell suspensions within the bioreactor produces a radial, convective flow and drag forces that result in the deposition of cells on the mandrel to form a tissue construct. Upon completion of the culture and tissue formation process, the tissue construct may be removed from the mandrel for subsequent in vivo use.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: October 21, 2008
    Assignee: La Jolla Bioengineering Institute
    Inventors: John A. Frangos, Peter Sobolewski
  • Publication number: 20060105452
    Abstract: The present invention provides for an improved in vitro tissue assembly system and related methods that includes and uses a bioreactor, a porous mandrel disposed in the bioreactor, and components that provide for the circulation of culture media and cell suspensions within the bioreactor and through the porous mandrel. The circulation of the culture media and cell suspensions within the bioreactor produces a radial, convective flow and drag forces that result in the deposition of cells on the mandrel to form a tissue construct. Upon completion of the culture and tissue formation process, the tissue construct may be removed from the mandrel for subsequent in vivo use.
    Type: Application
    Filed: November 16, 2004
    Publication date: May 18, 2006
    Inventors: John Frangos, Peter Sobolewski