Abstract: Methods for treating neurodegenerative diseases that can include targeting TANK Binding Kinase 1 (TBK1), I kappa B kinase (IKK), Signal Transducer and Activator of Transcription 1 (STAT1), or Janus Kinase 1 or Janus Kinase 2 (Jak1/2).

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: Disclosed are products and methods to facilitate the identification of compounds that are capable of interacting with biological macromolecules of interest, especially when such macromolecules are attached to a support surface in microarray. Aspects of the invention concern attachment chemistry, peptide labeling, antibody preparation, applications and so on.

Abstract: Apparatus for the determination of pO.sub.2 -histograms by means of a needle probe.The apparatus for the determination of pO.sub.2 -histograms in living tissue comprises a macro needle probe of larger diameter moved stepwise between individual measurement locations, the step widths being in the order of magnitude of the probe diameter and the speed being considerably higher than pO.sub.2 -changes within the tissue. Measured values are determined shortly after the probe has come to a standstill. Thus, disturbances in the tissue pO.sub.2 due to compression effects induced by the thick probe do not falsify the measured value although a thick and stable probe is used. A polarographic measuring site with a ring-shaped metal film electrode used here is characterized especially by a recessed metal ring electrode. By this means a measuring site of low stirring effect and very short response time is obtained.