Abstract: A surgical microscope includes an optical assembly to image an object plane with a microscope main objective system, through which a first stereoscopic partial beam path with a first optical axis and a second stereoscopic partial beam path with a second optical axis pass. An illumination device includes a light source assembly to provide illumination light in a luminous plane, with a radiant field stop, and an illumination optical unit which at least partially images a luminous object arranged in the luminous plane in the illumination beam path into a luminous image plane located in the microscope main objective system or for the vertical distance z of which from the microscope main objective system on the side facing the object region or the side facing away from the object region, in relation to a focal length f of the microscope main objective system, the following applies: z/f<10%.

Abstract: In one embodiment, a RF signal repeater switchable between SISO and MIMO comprises: a controller; a first transmitter path switchably coupled to first donor and coverage antennas; a second transmitter path switchably coupled to second donor and coverage antennas; a first receiver path switchably coupled to the first donor and coverage antennas; a second receiver path switchably coupled to the second donor and coverage antennas. The controller configures the repeater for a MIMO TDD operating mode by: configuring the first transmitter path and the second receiver path to repeat at least a first MIMO channel of UE uplink RF signals and at least a first MIMO channel of base station downlink RF signals; and configuring the second transmitter path and the first receiver path to repeat at least a second MIMO channel of UE uplink RF signals and at least a second MIMO channel of base station downlink RF signals.

Abstract: The present invention relates to pharmaceutical compositions comprising Akt protein kinase inhibitors with therapeutic activity against diseases such as cancer as well as processes for their preparation and their use as medicament.

Abstract: The present invention relates to pharmaceutical compositions comprising Akt protein kinase inhibitors with therapeutic activity against diseases such as cancer as well as processes for their preparation and their use as medicament.

Abstract: A football shoe or football boot including a sole, an upper, a fastener to fasten the shoe or boot in place, and a layer of material that in situ is disposed between the fastener and an underlying foot or hose. The layer of material includes a ball control region with an outer ball control surface contactable with a football during kicking. The ball control surface lies rearwardly of a foremost region of the layer of material.

Abstract: A football shoe or football boot includes a sole, and an upper including a throat region provided by flexible material of the upper, the throat region defining a boundary of the flexible material, with a canopy or tongue extending within the boundary, wherein the canopy or tongue includes a central portion and one or more protuberances disposed laterally of the central portion, the protuberances being formed of material added to material defining the canopy or tongue, wherein the central portion has none or a negligible amount of the added material forming the protuberances.

Abstract: A football shoe or football boot includes a sole and an upper. The upper includes a central region and one or more protuberances at each side of the central region. The one or more protuberances on each side define a crest alongside the central region, such that the crests and the central region define a ball control region. The protuberances are formed by incorporation of fluid material with the upper, in direct contact with the upper.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with a preservative that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with an excipient that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with a filler that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with an emollient that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with a solubilizer that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with a thickener that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with an antioxidant that specifically supports their viability during storage and/or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2,H3, K1,K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

Abstract: The present invention relates to pharmaceutical compositions comprising Akt protein kinase inhibitors with therapeutic activity against diseases such as cancer as well as processes for their preparation and their use as medicament.

Abstract: The present invention relates to pharmaceutical compositions comprising Akt protein kinase inhibitors with therapeutic activity against diseases such as cancer as well as processes for their preparation and their use as medicament.

Abstract: A football shoe or football boot includes a sole and an upper. The upper includes a central region and one or more protuberances at each side of the central region. The one or more protuberances on each side define a crest alongside the central region, such that the crests and the central region define a ball control region. The protuberances are formed by incorporation of fluid material with the upper, in direct contact with the upper.

Abstract: Disclosed is a cosmetic product comprising a metal can which comprises a metal container (A) which has a rotary thread (A?) and contains a cosmetic preparation as well as a lid (D) having a thread (D?) and being of the same metal as the container. The lid can be screwed onto/unscrewed from the container by means of threads (D?) and (A?) via rotational movement. The cosmetic preparation comprises an emulsion of one or more hydrophilic phases and one or more lipophilic phases. The one or more lipophilic phases comprise at least one lipid having a spreading coefficient at 25° C. of no more than 700 mm2/10 minutes, at least one lipid having a dropping point of >30° C., and at least one monovalent and/or polyvalent alcohol in a total amount of at least 3 wt. %.

Abstract: The present invention relates to pharmaceutical compositions comprising Akt protein kinase inhibitors with therapeutic activity against diseases such as cancer as well as processes for their preparation and their use as medicament.

Abstract: A football shoe or football boot including a sole, an upper, a fastening means to fasten the shoe or boot in place, and a layer of material that in situ is disposed between the fastening means and an underlying foot or hose, wherein the layer of material includes a ball control region with an outer ball control surface contactable with a football during kicking, and wherein said ball control surface lies rearwardly of a foremost region of the layer of material.