Abstract: The invention concerns a sensor arrangement (9) for an apparatus (1) for the additive manufacture of a component (2) in a manufacturing process in which build material (13), preferably comprising a metal powder, is consolidated on a construction area (8) in a processing area (3) by means of irradiation of the build material (13) with at least one energy beam (AL), the sensor arrangement (9) comprising: a sensor module (90) which is configured to detect oxygen molecules in a gas sample (P) permeating into the sensor module (90) and to generate an electrical sensor signal (S) based on the quantity of the oxygen molecules, a selective filter element (F) configured to filter the gas sample (P) so that at least hydrogen molecules and/or hydrogen ions and/or water molecules and/or hydroxide ions are filtered out of the gas sample (P). The invention further concerns a manufacturing apparatus as well as a measurement method with such a sensor arrangement.

Abstract: An optical measurement system measurement system for examining a sample. The measurement system comprises an internally reflective element, a stage, an optical assembly, a chassis, and a sensor. The internally reflective element has a contact surface. The stage is positioned below the internally reflective element. The stage and the internally reflective element are configured to apply a force to the sample. The optical assembly comprises a light source and a light detector. The optical assembly is configured to scan the sample by directing source light from the light source towards the contact surface and detecting source light optically interacting with the contact surface by the light detector. The chassis is configured to support the optical assembly and the internally reflective element. The sensor is mounted to the chassis and configured to detect the force applied to the sample by the internally reflective element and the stage.

Abstract: An embodiment of a microscope system is described that comprises a sample stage configured to position a sample; and a spectrometer comprising an interferometer configure to provide a light beam to the sample stage and one or more detectors configured to detect light spectra in response to the light beam, wherein the spectrometer sends a notification to the sample stage after a scan comprising an acceptable measure of quality has been acquired from the detected light spectra at a first location, and the sample stage is further configured to count the notifications and initiate movement of the sample stage to a second location when a count value reaches a pre-determined number.

Abstract: An optical measurement system measurement system for examining a sample. The measurement system comprises an internally reflective element, a stage, an optical assembly, a chassis, and a sensor. The internally reflective element has a contact surface. The stage is positioned below the internally reflective element. The stage and the internally reflective element are configured to apply a force to the sample. The optical assembly comprises a light source and a light detector. The optical assembly is configured to scan the sample by directing source light from the light source towards the contact surface and detecting source light optically interacting with the contact surface by the light detector. The chassis is configured to support the optical assembly and the internally reflective element. The sensor is mounted to the chassis and configured to detect the force applied to the sample by the internally reflective element and the stage.

Abstract: A measurement system configured to examine a sample. The system comprises an internally reflective element, a contact member, an actuator, an optical assembly, a sensor, and a controller. The contact member and the reflective element are configured to apply a force to the sample. The optical assembly is configured to scan the sample. Whereby prior to the scan, an initial force is applied to the sample, and after the scan, a resulting force is applied to the sample. The sensor is configured to detect the resulting force applied to the sample, and the controller is configured to receive a signal from the sensor indicative of the detected resulting force. The controller is further configured to control the actuator to adjust the force applied to the sample by the contact member and the internally reflective element from the resulting force to the initial force.

Abstract: An optical measurement system measurement system for examining a sample. The measurement system comprises an internally reflective element, a stage, an optical assembly, a chassis, and a sensor. The internally reflective element has a contact surface. The stage is positioned below the internally reflective element. The stage and the internally reflective element are configured to apply a force to the sample. The optical assembly comprises a light source and a light detector. The optical assembly is configured to scan the sample by directing source light from the light source towards the contact surface and detecting source light optically interacting with the contact surface by the light detector. The chassis is configured to support the optical assembly and the internally reflective element. The sensor is mounted to the chassis and configured to detect the force applied to the sample by the internally reflective element and the stage.

Abstract: A measurement system configured to examine a sample. The system comprises an internally reflective element, a contact member, an actuator, an optical assembly, a sensor, and a controller. The contact member and the reflective element are configured to apply a force to the sample. The optical assembly is configured to scan the sample. Whereby prior to the scan, an initial force is applied to the sample, and after the scan, a resulting force is applied to the sample. The sensor is configured to detect the resulting force applied to the sample, and the controller is configured to receive a signal from the sensor indicative of the detected resulting force. The controller is further configured to control the actuator to adjust the force applied to the sample by the contact member and the internally reflective element from the resulting force to the initial force.

Abstract: An embodiment of a microscope system is described that comprises a sample stage configured to position a sample; and a spectrometer comprising an interferometer configure to provide a light beam to the sample stage and one or more detectors configured to detect light spectra in response to the light beam, wherein the spectrometer sends a notification to the sample stage after a scan comprising an acceptable measure of quality has been acquired from the detected light spectra at a first location, and the sample stage is further configured to count the notifications and initiate movement of the sample stage to a second location when a count value reaches a pre-determined number.

Abstract: The present invention relates to a pharmaceutical composition comprising complement split product C4d for use in treating an inflammatory condition, such as graft rejection, graft versus host disease, an autoimmune disease or atopy. The C4d to be used may be a multimer. Accordingly, also C4d multimers and their use in medicine, like the treatment of inflammatory conditions, is provided. Furthermore, the present invention provides a protein complex comprising C4d interacting with its ILT4 receptor. This protein complex may be used in screening methods Also antibodies specifically binding to the C4d multimer or the C4d/ILT4-protein complex are subject of the present invention.

Abstract: A computer-assisted method, computer system, and program product provide the functionality of a portal for persons to find, based on a topic of interest, the nearest relevant in-person gathering of other persons interested in the topic as well. The system provides for the automated creation of groups and for their automatic sustainment through automatic scheduling of periodic gatherings. Strangers in geographic proximity are automatically brought together into chapters formed around the topic of interest. Chapters may be led by organizers, and gatherings may have hosts. Automatic functions for venue selection, venue voting, cancellation, and feedback are provided.

Abstract: The present invention relates to a pharmaceutical composition comprising complement split product C4d for use in treating an inflammatory condition, such as graft rejection, graft versus host disease, an autoimmune disease or atopy. The C4d to be used may be a multimer. Accordingly, also C4d multimers and their use in medicine, like the treatment of inflammatory conditions, is provided. Furthermore, the present invention provides a protein complex comprising C4d interacting with its ILT4 receptor. This protein complex may be used in screening methods Also antibodies specifically binding to the C4d multimer or the C4d/ILT4-protein complex are subject of the present invention.

Abstract: The present invention relates to a pharmaceutical composition comprising complement split product C4d for use in treating an inflammatory condition, such as graft rejection, graft versus host disease, an autoimmune disease or atopy. The C4d to be used may be a multimer. Accordingly, also C4d multimers and their use in medicine, like the treatment of inflammatory conditions, is provided. Furthermore, the present invention provides a protein complex comprising C4d interacting with its ILT4 receptor. This protein complex may be used in screening methods Also antibodies specifically binding to the C4d multimer or the C4d/ILT4-protein complex are subject of the present invention.

Abstract: A computer-assisted method, computer system, and program product provide the functionality of a portal for persons to find, based on a topic of interest, the nearest relevant in-person gathering of other persons interested in the topic as well. The system provides for the automated creation of groups and for their automatic sustainment through automatic scheduling of periodic gatherings. Strangers in geographic proximity are automatically brought together into chapters formed around the topic of interest. Chapters may be led by organizers, and gatherings may have hosts. Automatic functions for venue selection, venue voting, cancellation, and feedback are provided.

Abstract: A computer-assisted method, computer system, and program product provide the functionality of a portal for persons to find, based on a topic of interest, the nearest relevant in-person gathering of other persons interested in the topic as well. The system provides for the automated creation of groups and for their automatic sustainment through automatic scheduling of periodic gatherings. Strangers in geographic proximity are automatically brought together into chapters formed around the topic of interest. Chapters may be led by organizers, and gatherings may have hosts. Automatic functions for venue selection, venue voting, cancellation, and feedback are provided.

Abstract: The present invention relates to a pharmaceutical composition comprising complement split product C4d for use in treating an inflammatory condition, such as graft rejection, graft versus host disease, an autoimmune disease or atopy. The C4d to be used may be a multimer. Accordingly, also C4d multimers and their use in medicine, like the treatment of inflammatory conditions, is provided. Furthermore, the present invention provides a protein complex comprising C4d interacting with its ILT4 receptor. This protein complex may be used in screening methodsAlso antibodies specifically binding to the C4d multimer or the C4d/ILT4-protein complex are subject of the present invention.

Abstract: The present invention relates to group 2 allergen specific IgE-Fabs and whole Ig molecules as well as use thereof. More precisely, the present invention relates to grass pollen specific IgE-Fabs (Phl p2) and reagents, kits and vaccines comprising these. The invention also relates to use of group 2 specific IgE-Fabs and whole Ig for, inter alia, diagnosis, therapy and prevention of type I allergy.

Abstract: A range of extruded polymers incorporating synthetic furanones was manufactured and field tested. Polymers incorporating furanones showed excellent antifouling efficacy and significantly reduced fouling for more than 100 days. The present inventors have developed polymers that release commercial short-lived biocides or analogues of antifouling compounds isolated from marine algae. A range of polymers incorporating either the commercial isothiazolone Sea-Nine 211™ or a halogenated furanone were effective antifouling treatments in laboratory and field trials. The efficacy of the polymers was dependant on polymer type and the initial concentration of the antifouling compound. The polymers can be extruded as filaments that can be woven into netting or extruded or molding for other applications.

Abstract: The present invention relates to group 2 allergen specific IgE-Fabs and whole Ig molecules as well as use thereof. More precisely, the present invention relates to grass pollen specific IgE-Fabs (Phl p2) and reagents, kits and vaccines comprising these. The invention also relates to use of group 2 specific IgE-Fabs and whole Ig for, inter alia, diagnosis, therapy and prevention of type I allergy.

Abstract: A method for inhibiting, diminishing, preventing or treating pathogenic infection of cells comprising expressing a recombinant antibody protein fused to an intracellular anchor means, wherein said antibody is specific for a surface receptor of said cells necessary for pathogenic infection, wherein said antibody is suitably selected from CCR5 and CXCR4 specific antibodies. A recombinant antibody protein fused to an intracellular anchor means which is specific for a surface receptor necessary for pathogenic infection, but suitably elected from CCR5 and CXCR4 specific antibodies and humanized antibodies therefrom. A recombinant antibody that immunoreacts with CCR5 or CXCR4 surface receptor. Peptides comprising at least YTSF or YTSQ sequence for use in a vaccine or an immunogenic composition intended to control, prevent, diminish or treat HIV infections. An antiidiotypic antibody mimicking CCR5 or CXCR4 epitopes raised from anti-CCR5 and anti-CXCR4 antibodies.

Abstract: An evaporation cooling system for an internal-combustion engine controls venting through a valve as a function of the temperature. The escape of water vapor is prevented when the vent valve is not yet actuated.