Abstract: A particularly reliable quick release latch and a release mechanism, as well as a quick grounding device or short circuiter, is particularly suited for low, medium, and/or high-voltage applications.

Abstract: A method for the treatment of cancer by administering a therapeutically effective amount of a cyclin-dependent kinase (CDK) inhibitor with a therapeutically effective amount of a B cell chronic lymphocytic leukemia/lymphoma 2 inhibitor (“B Cell CLL/Lymphoma 2”, or “BCL-2”). Administration of the CDK inhibitor and BCL-2 inhibitor can be simultaneous, successive or separate.

Abstract: The invention relates to a method for producing sandwich construction elements for substantially load-bearing and self-supporting building parts. In one embodiment of the invention, a method is provided including a) producing at least one layer of a mechanically bonded fiber nonwoven which is impregnated with a binder based on at least one heat-curable resin system b) curing the heat-curable resin system in order to produce at least one hardened layer of the fiber nonwoven, and fixed thermally, c) bringing a heat-foamable or heat-foamed phenol resin into contact with that surface of at least one hardened layer of the fiber nonwoven which has been modified according to step b), d) possibly annealing the composite produced in a) to c), and e) curing the further binder based on at least one heat-curable resin system.

Abstract: A method for the treatment of cancer by administering a therapeutically effective amount of a cyclin-dependent kinase (CDK) inhibitor with a therapeutically effective amount of a B cell chronic lymphocytic leukemia/lymphoma 2 inhibitor (“B Cell CLL/Lymphoma 2”, or “BCL-2”). Administration of the CDK inhibitor and BCL-2 inhibitor can be simultaneous, successive or separate.

Abstract: The invention relates to a method for producing sandwich construction elements for substantially load-bearing and self-supporting building parts.

Abstract: The invention relates to a ceramic product, manufactured from a mixture made of natural and/or synthetic inorganic non-metal raw materials, at least one binder and optionally further additives. In order to provide ceramic products allowing for disadvantages known from the prior art to be eliminated, at least with respect to corrosion and erosion, it is proposed that the ceramic products are manufactured from a mixture comprising a) at least 10% by weight (based on the weight of all solids of the mixture) oxidic components, b) 0.05 to 2.7% by weight (based on the weight of all solids of the mixture) at least one organic-based binder, acting as a solubilizer in the mixture, and c) 3 to 10% by weight (based on the weight of all solids of the mixtures) hydrous dispersing agent, and that the ceramic product contains less than 0.1% by weight (based on the total weight of the ceramic product) of carbon after the use thereof at temperatures above 600° C.

Abstract: The invention relates to watery resin dispersions, a process for their manufacture, and a product. To make available resin dispersions that do not pollute the environment during their processing, while simultaneously generating products that have a high glass transition temperature, it is suggested that the watery resin dispersion contain at least components (I), (II) and (III), whereby R1: unsubstituted single or polynuclear aromatic rest or with amino groups and/or cyano groups and/or nitrile groups and/or with saturated and/or unsaturated aliphatic C2 to C12 carbon chains substituted single or polynuclear aromatic rests R2, R3 and R4: hydrogen, alkyl residue group with up to 15 C atoms or aromatic rest whereby R2, R3 and R4 can be equal to or different from each other, (II) is a co-dispersion agent based on epoxide resins and/or novolak resins and (II) one surfactant.

Abstract: An elevation measuring device comprises a measuring column at which a vertically movable measuring slide is supported, so it can be moved by hand and also by a drive motor through a clutch device. The measuring slide supports a scan head, which imparts a constant measuring force onto the measuring location at the work piece, which is generated by the drive motor and the clutch device. A measuring system detects the elevation coordinate of the scan head and hands said elevation coordinate to a control device for further processing and evaluation. The control device comprises logic for automating the measuring process. This logic automatically detects a positioning of the scan head in a certain direction, which is manually performed by the operator, subsequently controls the drive motor in a suitable manner in order to cause a scanning of the work piece and determines the measurement values.

Abstract: The invention relates to the identification and use of gene expression profiles with clinical relevance to the treatment of cellular proliferative disorders, especially those mediated by aberrant Notch signaling using a Notch signaling inhibitor. In particular, the invention provides the identities of genes, whose individual or cumulative expression patterns may be useful in various assays. The gene expression profiles, whether embodied in nucleic acid expression, protein expression, or other expression formats, may be used to select subjects afflicted with a Notch mediated cancer who will likely respond to treatment with a gamma-secretase inhibitor or another Notch inhibiting agent. The same markers may be used in the classification of patients being treated with other Notch inhibitors. The methods may further comprise providing diagnostic, prognostic, or predictive information based on the classifying step. The methods may further comprise selecting a treatment based on the classifying step.

Abstract: The invention relates to watery resin dispersions, a process for their manufacture, and a product. To make available resin dispersions that do not pollute the environment during their processing, while simultaneously generating products that have a high glass transition temperature, it is suggested that the watery resin dispersion contain at least components (I), (II) and (III), whereby R1: unsubstituted single or polynuclear aromatic rest or with amino groups and/or cyano groups and/or nitrile groups and/or with saturated and/or unsaturated aliphatic C2 to C12 carbon chains substituted single or polynuclear aromatic rests R2, R3 and R4: hydrogen, alkyl residue group with up to 15 C atoms or aromatic rest whereby R2, R3 and R4 can be equal to or different from each other, (II) is a co-dispersion agent based on epoxide resins and/or novolak resins and (II) one surfactant.

Abstract: An elevation measuring device (1) comprises a measuring column (3) at which a vertically movable measuring slide (4) is supported, so it can be moved by hand and also by a drive motor (14) through a clutch device (15). The measuring slide (4) supports a scan head (8), which imparts a constant measuring force onto the measuring location at the work piece, which is generated by the drive motor (14) and the clutch device (15). A measuring system (19) detects the elevation coordinate of the scan head (8) and hands said elevation coordinate to a control device (21) for further processing and evaluation. The control device (21) comprises logic (33) for automating the measuring process.

Abstract: A distance measuring system (1) is provided with a capacitive sensor (7a, 7b), designed in the form of a differential capacitor (18), for which the partial capacitors (C1, C2 have capacitances that depend on the position to be determined. The system also includes a processing device (5) for determining the desired distance that contains, for example, a sigma/delta demodulator. The partial capacitors (C1, C2) are triggered periodically with binary signals, wherein the trigger signals from the one partial capacitor (C1) are transmitted with a phase offset to the signals from the other partial capacitor (C2). The processing device (5) determines which trigger signals must be used for the evaluation. Within time windows that are synchronized with the edges of the trigger signals, a switch unit (22) allows the associated receiving signals to pass through to the processing unit (5) and blanks out all other signals.

Abstract: A distance measuring system (1) is provided with a capacitive sensor (7a, 7b), designed in the form of a differential capacitor (18), for which the partial capacitors (C1, C2 have capacitances that depend on the position to be determined. The system also comprises a processing device (5) for determining the desired distance that contains, for example, a sigma/delta demodulator. The partial capacitors (C1, C2) are triggered periodically with binary signals, wherein the trigger signals from the one partial capacitor (C1) are transmitted with a phase offset to the signals from the other partial capacitor (C2). The processing device (5) determines which trigger signals must be used for the evaluation. Within time windows that are synchronized with the edges of the trigger signals, a switch unit (22) allows the associated receiving signals to pass through to the processing unit (5) and blanks out all other signals.

Abstract: A multiple pig subsea pig launcher is disclosed. The pig launcher can be assembled on a production pipeline subsea with the aid of an ROV. In the preferred embodiment, the pigs are connected to each other and spaced apart by a spine. The pig launcher is configured to capture the next pig to be launched in such a manner that the spine behind it is in alignment with a shearing valve; for example, coiled tubing or wireline. Sequential valve operation shears the spine and applies pressure behind the pig to launch it from the launcher past the pig detector and onto a platform for recapture.

Abstract: A subsea pig launcher, that can launch either 1 or more pipeline pigs simultaneously. The pig launcher can be assembled on a subseas production pipeline with the aid of an ROV. In the preferred embodiment, the pigs are connected to each other and spaced apart by a spine. The pig launcher is configured to capture the next pig to be launched in such a manner that the spine behind it is in alignment with a shearing valve; for example, coiled tubing or wireline. Sequential valve operation shears the spine and applies pressure behind the pig to launch it from the launcher past the pig detector and onto a platform for recapture.

Abstract: The bonding agent composition comprises tannin of pine bark and/or pecan nut, paraformaldehyde and an ammonium salt of a weak acid. It serves inter alia as bonding agent for particle board with high transverse tensile strength, good water resistance and low formaldehyde emission.

Abstract: A capacitive measuring device or apparatus; in particular, a length-measuring apparatus, which incorporates a scale portion and a scanning unit which is movable relative to the former and which supports transmitting electrodes and at least one receiving electrode. Herein, a transmission circuit applies transmitting signals at a basic frequency to the transmitting electrodes, and with the receiving electrode being connected to a reception circuit, to the output side of which there is connected an evaluating circuit for the receiving signals. The transmitting signals are applied to the transmitting electrodes through a pulse width modulator and a synchronous modulator and the receiving signal is conducted through a demodulator.