Patents by Inventor Peter T. HRABER

Peter T. HRABER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising HIV envelopes to induce CH235 lineage antibodies
    Patent number: 11884704
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including HIV-1 envelope selections from individual CH505, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: January 30, 2024
    Assignees: DUKE UNIVERSITY, TRIAD NATIONAL SECURITY, LLC
    Inventors: Barton F. Haynes, Mattia Bonsignori, Hua-Xin Liao, Bette T. Korber, Peter T. Hraber, Kevin O. Saunders
  • Compositions and methods for inducing HIV-1 antibodies
    Patent number: 11246920
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH0848) and selections there—from, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: February 15, 2022
    Assignees: Duke University, Triad National Security, LLC
    Inventors: Barton F. Haynes, Mattia Bonsignori, Bette T. Korber, Peter T. Hraber, Kevin Saunders
  • COMPOSITIONS COMPRISING HIV ENVELOPES TO INDUCE CH235 LINEAGE ANTIBODIES
    Publication number: 20210277065
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including HIV-1 envelope selections from individual CH505, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Application
    Filed: March 11, 2021
    Publication date: September 9, 2021
    Inventors: Barton F. HAYNES, Mattia BONSIGNORI, Hua-Xin LIAO, Bette T. KORBER, Peter T. HRABER, Kevin O. SAUNDERS
  • COMPOSITIONS AND METHODS FOR INDUCING HIV-1 ANTIBODIES
    Publication number: 20210187091
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH0848) and selections therefrom, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Application
    Filed: March 3, 2017
    Publication date: June 24, 2021
    Inventors: Barton F. HAYNES, Mattia BONSIGNORI, Bette T. KORBER, Peter T. HRABER, Kevin SAUNDERS
  • Compositions comprising HIV envelopes to induce CH235 lineage antibodies
    Patent number: 10968255
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including HIV-1 envelope selections from individual CH505, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: April 6, 2021
    Assignees: Duke University, Triad National Security, LLC
    Inventors: Barton F. Haynes, Mattia Bonsignori, Hua-Xin Liao, Bette T. Korber, Peter T. Hraber, Kevin Saunders
  • COMPOSITIONS COMPRISING HIV ENVELOPES TO INDUCE CH235 LINEAGE ANTIBODIES
    Publication number: 20200002383
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including HIV-1 envelope selections from individual CH505, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Application
    Filed: March 1, 2017
    Publication date: January 2, 2020
    Inventors: Barton F. HAYNES, Mattia BONSIGNORI, Hua-Xin LIAO, Bette T. KORBER, Peter T. HRABER, Kevin SAUNDERS
  • Compositions comprising CH848 envelopes and uses thereof
    Patent number: 10322141
    Abstract: In certain aspects the invention provides immunogenic compositions comprising CH848 HIV-1 envelopes and their use in methods to induce immune responses in subjects, e.g., human subjects.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: June 18, 2019
    Assignees: DUKE UNIVERSITY, TRIAD NATIONAL SECURITY, LLC, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Barton F. Haynes, Beatrice H. Hahn, George M. Shaw, Bette T. Korber, Peter T. Hraber
  • Compositions comprising CH505 envelopes, and trimers
    Patent number: 10232034
    Abstract: In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogens comprise an immune modulating component.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: March 19, 2019
    Assignees: DUKE UNIVERSITY, LOS ALAMOS NATIONAL SECURITY, LLC
    Inventors: Barton F. Haynes, Hua-Xin Liao, Bette T. Korber, Peter T. Hraber
  • Swarm immunization with envelopes from CH505
    Patent number: 10149902
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH505) and selections therefrom, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: December 11, 2018
    Assignees: DUKE UNIVERSITY, LOS ALAMOS NATIONAL SECURITY, LLC
    Inventors: Barton F. Haynes, Feng Gao, Bette T. Korber, Peter T. Hraber
  • COMPOSITIONS COMPRISING CH505 ENVELOPES, AND TRIMERS (EIGHT VALENT HIV-1 COMPOSITION AND METHODS)
    Publication number: 20180271973
    Abstract: In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens in vaccination to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogens and methods of using these comprise an immune modulating component.
    Type: Application
    Filed: December 23, 2015
    Publication date: September 27, 2018
    Inventors: Barton F. HAYNES, Hua-Xin LIAO, Bette T. KORBER, Peter T. HRABER
  • SWARM IMMUNIZATION WITH 54 ENVELOPES FROM CH505
    Publication number: 20170326229
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH505) and selections therefrom, and methods for swami immunizations using combinations of HIV-1 envelopes.
    Type: Application
    Filed: September 29, 2015
    Publication date: November 16, 2017
    Inventors: Barton F. HAYNES, Bette T. KORBER, Peter T. HRABER, Hua-Xin LIAO
  • COMPOSITIONS COMPRISING CH848 ENVELOPES AND USES THEREOF
    Publication number: 20170312303
    Abstract: In certain aspects the invention provides immonogenic compositions comprising CH848 HIV-1 envelopes and their use in methods to induce immune responses in subjects, e.g., human subjects.
    Type: Application
    Filed: March 31, 2015
    Publication date: November 2, 2017
    Inventors: Barton F. HAYNES, Beatrice H. HAHN, George M. SHAW, Bette T. KORBER, Peter T. HRABER
  • COMPOSITIONS COMPRISING CH505 ENVELOPES, AND TRIMERS
    Publication number: 20170281749
    Abstract: In certain aspects the invention provides a selection of HIV-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogens comprise an immune modulating component.
    Type: Application
    Filed: September 25, 2015
    Publication date: October 5, 2017
    Applicants: Duke University, Los Alamos National Security, LLC
    Inventors: Barton F. HAYNES, Hua-Xin LIAO, Bette T. KORBER, Peter T. HRABER
  • SWARM IMMUNIZATION WITH ENVELOPES FROM CH505
    Publication number: 20170080082
    Abstract: In certain aspects the invention provides HIV-1 immunogens, including envelopes (CH505) and selections therefrom, and methods for swarm immunizations using combinations of HIV-1 envelopes.
    Type: Application
    Filed: March 19, 2015
    Publication date: March 23, 2017
    Inventors: Barton F. HAYNES, Feng GAO, Bette T. KORBER, Peter T. HRABER