Patents by Inventor Peter Timmerman
Peter Timmerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12132253Abstract: A metasurface includes a dielectric material, a ground plane on a back side of the dielectric material; and at least one conductive element on a top surface of the dielectric material, wherein the at least one conductive element includes at least one of a ground-backed dipole or a slot array.Type: GrantFiled: October 19, 2021Date of Patent: October 29, 2024Assignee: Hitachi Rail GTS Canada Inc.Inventors: Alon Ion Green, Peter Timmermans, Walter Kinio, Alex M. H. Wong, Philip Christian, George V. Eleftheriades
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Patent number: 11608097Abstract: A system comprises a set of sensors on a first end of a vehicle having the first end and a second end, and a controller. The sensors are configured to generate corresponding sensor data based on a detected object along a direction of movement of the vehicle. The controller is configured to compare a time at which the first sensor detected the object with a time at which the second sensor detected the object to identify the first end or the second end as a leading end of the vehicle, and to calculate a position of the leading end of the vehicle based on the sensor data generated by one or more of the first sensor or the second sensor. The controller is also configured to generate a map of the plurality of objects based on the sensor data.Type: GrantFiled: February 28, 2018Date of Patent: March 21, 2023Assignee: THALES CANADA INCInventors: Alon Green, Walter Kinio, Peter Timmermans
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Patent number: 11503058Abstract: A security server for dynamic verification of web content located on a platform in the cloud or in the edge which runs artificial intelligence (AI) algorithms including a collector receiving collection of user interactions from an adapted browser of a remote to simulate content of pages loaded on the device based on user interactions from an adapted browser located on the end-user device navigating on the web and for sampling the outcome of these interactions at irregular time intervals, this sample resulting a fixed image such as JPG or PNG, a data mining and artificial intelligence (AI) algorithm relying on image processing executed while sample interval to detect object or patterns on the displayed content, a heartbeat generator generates heartbeat at regular interval and transmits at a continuous interval to the end-user's device to indicate to the adapted browser of the device it may display the content.Type: GrantFiled: August 19, 2020Date of Patent: November 15, 2022Assignee: INGENICO BELGIUMInventors: Mohamed Amine Youssef, Gert-Jan Andries, Cédric Meuter, Peter Timmermans
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Publication number: 20220098232Abstract: The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.Type: ApplicationFiled: October 5, 2021Publication date: March 31, 2022Inventors: Gaston Julia Johannes Richelle, Dieuwertje Emma Streefkerk, Jan Herman Van Maarseveen, Peter Timmerman
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Patent number: 11254338Abstract: A system comprises a first sensor on a first end of a vehicle and an on-board controller coupled to the first sensor. The first sensor is configured to detect a radio frequency (RF) signature of a marker along a guideway. The first sensor is a radar detection device. The on-board controller is configured to determine a first position of the vehicle on the guideway or a first distance from the position of the vehicle to a stopping location along the guideway based on at least the RF signature received from the first sensor. The marker is a metasurface plate comprising a first diffused element, a first retroreflector element, a first absorbing element and a second diffused element between the first retroreflector element and the first absorbing element.Type: GrantFiled: September 26, 2018Date of Patent: February 22, 2022Assignee: THALES CANADA INC.Inventors: Alon Green, Walter Kinio, Peter Timmermans
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Patent number: 11192918Abstract: The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.Type: GrantFiled: December 6, 2017Date of Patent: December 7, 2021Assignees: Stichting voor de Technische Wetenschappen, Universiteit van AmsterdamInventors: Gaston Julia Johannes Richelle, Dieuwertje Emma Streefkerk, Jan Herman van Maarseveen, Peter Timmerman
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Patent number: 11183769Abstract: A metasurface includes a dielectric material, a ground plane on a back side of the dielectric material; and at least one conductive element on a top surface of the dielectric material, wherein the at least one conductive element includes at least one of a ground-backed dipole or a slot array.Type: GrantFiled: October 26, 2018Date of Patent: November 23, 2021Assignee: THALES CANADA INC.Inventors: Alon Green, Peter Timmermans, Walter Kinio, Alex M. H. Wong, Philip Christian, George V. Eleftheriades
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Publication number: 20200239516Abstract: The invention relates to methods for preparing a compound comprising a peptide attached to a molecular scaffold whereby multiple peptide loops are formed, to compounds that can be obtained with such methods and uses thereof.Type: ApplicationFiled: December 6, 2017Publication date: July 30, 2020Inventors: Gaston Julia Johannes Richelle, Dieuwertje Emma Streefkerk, Jan Herman van Maarseveen, Peter Timmerman
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Patent number: 9176127Abstract: The disclosure relates to the field of candidate drug testing and drug development. A method is provided for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule capable of reacting with the at least first and second reactive group; contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the at least one molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage, preferably wherein the coupling reaction is performed in solution, more preferably in an aqueous solution. Furthermore, a method is provided for selecting a candidate drug compound comprising providing a library of compounds hereof and determining the binding of a target molecule to the compounds.Type: GrantFiled: March 7, 2014Date of Patent: November 3, 2015Assignee: Pepscan Systems B.V.Inventors: Peter Timmerman, Joris Beld, Robbert H. Meloen, Wouter C. Puijk
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Publication number: 20140357577Abstract: The present invention concerns an inhibitor of Human Immunodeficiency Virus (HIV) fusion with, or HIV entry in, a host cell comprising at least 24, but preferably 26, contiguous amino acids; the invention also relates to a pharmaceutical composition comprising said amino acids.Type: ApplicationFiled: December 18, 2012Publication date: December 4, 2014Inventors: Bruce Albert Malcolm, Johannes Wilhelmus J. Thuring, Christophe Francis Robert Nestor Buyck, Wim Bert Griet Schepens, Maria Aldegonda Jacoba Kriek, Wilhelmus Martinus Maria Schaaper, Jelle Wouter Slootstra, Peter Timmerman
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Publication number: 20140308303Abstract: The disclosure relates to the field of candidate drug testing and drug development. A method is provided for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule capable of reacting with the at least first and second reactive group; contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the at least one molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage, preferably wherein the coupling reaction is performed in solution, more preferably in an aqueous solution. Furthermore, a method is provided for selecting a candidate drug compound comprising providing a library of compounds hereof and determining the binding of a target molecule to the compounds.Type: ApplicationFiled: March 7, 2014Publication date: October 16, 2014Inventors: Peter TIMMERMAN, Joris BELD, Robbert H. MELOEN, Wouter C. PUIJK
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Publication number: 20140296478Abstract: The disclosure relates to the field of candidate drug testing and drug development. Described are methods for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule able to react with the at least first and second reactive group; and contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage. The coupling reaction may be performed in solution, such as an aqueous solution. Furthermore, described is a method for selecting a candidate drug compound comprising providing a library of the compounds and determining the binding of a target molecule to the compounds.Type: ApplicationFiled: March 7, 2014Publication date: October 2, 2014Applicant: PEPSCAN SYSTEMS B.V.Inventors: Peter TIMMERMAN, Joris BELD, Robbert H. MELOEN, Wouter C. PUIJK
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Patent number: 8772236Abstract: The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further, the invention relates to the use of these proteinmimics as a medicament or prophylactic agent. The invention provides proteinmimics of members of the cystine-knot growth factor superfamily, preferably for use in immunogenic and/or therapeutic compositions.Type: GrantFiled: February 5, 2010Date of Patent: July 8, 2014Assignees: Pepscan Systems B.V., Universiteit Maastricht, Academisch Ziekenhuis MaastrichtInventors: Peter Timmerman, Wouter C. Puijk, Tilman M. Hackeng, Arjan W. Griffioen
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Patent number: 8748105Abstract: The invention relates to the field of candidate drug testing and drug development. A method is provided for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule capable of reacting with the at least first and second reactive group; contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the at least one molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage, preferably wherein the coupling reaction is performed in solution, more preferably in an aqueous solution. Furthermore, a method is provided for selecting a candidate drug compound comprising providing a library of compounds according to the invention and determining the binding of a target molecule to the compounds.Type: GrantFiled: August 26, 2005Date of Patent: June 10, 2014Assignee: Pepscan Systems B.V.Inventors: Peter Timmerman, Joris Beld, Robbert Hans Meloen, Wouter Cornelis Puijk
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Patent number: 8742070Abstract: The disclosure relates to the field of candidate drug testing and drug development. Described are methods for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule able to react with the at least first and second reactive group; and contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage. The coupling reaction may be performed in solution, such as an aqueous solution. Furthermore, described is a method for selecting a candidate drug compound comprising providing a library of the compounds and determining the binding of a target molecule to the compounds.Type: GrantFiled: April 10, 2012Date of Patent: June 3, 2014Assignee: Pepscan Systems B.V.Inventors: Peter Timmerman, Joris Beld, Robbert Hans Meloen, Wouter Cornelis Puijk
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Publication number: 20130158232Abstract: The disclosure relates to the field of candidate drug testing and drug development. Described are methods for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule able to react with the at least first and second reactive group; and contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage. The coupling reaction may be performed in solution, such as an aqueous solution. Furthermore, described is a method for selecting a candidate drug compound comprising providing a library of the compounds and determining the binding of a target molecule to the compounds.Type: ApplicationFiled: April 10, 2012Publication date: June 20, 2013Inventors: Peter TIMMERMAN, Joris Beld, Robbert Hans Meloen, Wouter Cornelis Puijk
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Publication number: 20120231000Abstract: The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further, the invention relates to the use of these proteinmimics as a medicament or prophylactic agent. The invention provides proteinmimics of members of the cystine-knot growth factor superfamily, preferably for use in immunogenic and/or therapeutic compositions.Type: ApplicationFiled: February 5, 2010Publication date: September 13, 2012Inventors: Peter Timmerman, Wouter C. Puijk, Tilman M. Hackeng, Arjan W. Griffioen
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Patent number: 7863239Abstract: The invention provides means and methods for producing compounds suitable for testing for the presence and/or identification of an immunogenic compound and/or a binding compound of interest. Immunogenic compounds and compositions are also herewith provided, as well as peptidomimetics of members of the cystine-knot family.Type: GrantFiled: January 24, 2006Date of Patent: January 4, 2011Assignee: Pepscan Systems B.V.Inventors: Peter Timmerman, Wouter Cornelis Puijk, Jelle Wouter Slootstra, Evert van Dijk, Robbert Hans Meloen
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Publication number: 20100322945Abstract: The invention provides means and methods for inducing and/or enhancing immunogenic reproducibility and/or immunogenicity of a compound, comprising at least in part restricting the conformation of said compound. The conformation is preferably restricted by the formation of at least one internal bond within said compound. Protein mimics comprising an amino acid sequence bound to a scaffold and/or a carrier, wherein said amino acid sequence comprises at least one internal SS-bridge, are also herewith provided.Type: ApplicationFiled: July 26, 2007Publication date: December 23, 2010Inventors: Peter Timmerman, Wouter Cornelis Puijk, Robbert Hans Meloen
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Patent number: 7555617Abstract: An electronic data processing device includes a data processing member provided for controlling, based on first and second encoded data, a secured operation initiated by a user, a memory which is configurable in order to delimit at least one secured memory part within that memory, to each secured memory parts there being assigned a dedicated address range. The data processing member includes N (N?2) processing units of which M (M?N?1) processing units are provided to process the secured operation and at least one of the remaining N-M processing units is provided for processing application data, to each of the M processing units there is assigned at least one of the secured memory parts via of a configuration element controlled by a selected one of the M processing units. The second memory is provided with a memory access controller provided for controlling access to the second memory.Type: GrantFiled: December 13, 2004Date of Patent: June 30, 2009Assignee: ATOS Worldline SAInventors: Peter Timmermans, Carl Van Himbeeck, Mark Vanophalvens