Abstract: The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further, the invention relates to the use of these proteinmimics as a medicament or prophylactic agent. The invention provides proteinmimics of members of the cystine-knot growth factor superfamily, preferably for use in immunogenic and/or therapeutic compositions.

Abstract: The invention provides means and methods for producing compounds suitable for testing for the presence and/or identification of an immunogenic compound and/or a binding compound of interest. Immunogenic compounds and compositions are also herewith provided, as well as peptidomimetics of members of the cystine-knot family.

Abstract: The invention provides means and methods for inducing and/or enhancing immunogenic reproducibility and/or immunogenicity of a compound, comprising at least in part restricting the conformation of said compound. The conformation is preferably restricted by the formation of at least one internal bond within said compound. Protein mimics comprising an amino acid sequence bound to a scaffold and/or a carrier, wherein said amino acid sequence comprises at least one internal SS-bridge, are also herewith provided.

Abstract: An electronic data processing device includes a data processing member provided for controlling, based on first and second encoded data, a secured operation initiated by a user, a memory which is configurable in order to delimit at least one secured memory part within that memory, to each secured memory parts there being assigned a dedicated address range. The data processing member includes N (N?2) processing units of which M (M?N?1) processing units are provided to process the secured operation and at least one of the remaining N-M processing units is provided for processing application data, to each of the M processing units there is assigned at least one of the secured memory parts via of a configuration element controlled by a selected one of the M processing units. The second memory is provided with a memory access controller provided for controlling access to the second memory.

Abstract: The invention provides means and methods for producing compounds suitable for testing for the presence and/or identification of an immunogenic compound and/or a binding compound of interest. Immunogenic compounds and compositions are also herewith provided, as well as peptidomimetics of members of the cystine-knot family.

Abstract: An electronic data processing device, comprising an access protected memory, provided for storing secure data and a data processing member, provided for processing said secure data, said terminal comprises a tampering detection and protection circuit provided for detecting a tamper condition and for generating a tamper signal upon detection of said tamper condition, said tampering detection and protection circuit being connected to a tampering sequencer, provided for disabling said processing member upon receipt of said tampering signal, said memory comprises a security register provided for storing keys for encrypting said secure data and a memory section provided for storing keys for encrypting said secure data and a memory section provided for temporarily storing secure data processed by said data processing member, said tampering sequencer comprises an internal clock generator provided for generating, upon receipt of said tamper signal a tamper pulse and a series of clock pulses, said tampering sequencer

Abstract: A method and a device for reading out keys of a keyboard. The read-out is realised by randomly generating a scanning pattern comprising for each row and column a read-out value to be applied on the rows and columns. The scanning pattern is preferably changed after having been applied to the keys. After application of the randomly generated pattern, the verification routine is applied in order to identify the selected keys.

Abstract: The present invention pertains to antigenic peptides of SARS-CoV and their use in diagnostic test methods and in the treatment of condition resulting from SARS-CoV. Furthermore, this invention provides antibodies capable of specifically recognizing the peptides of the invention. The antibodies can also advantageously be used in diagnostic test methods and in the treatment of condition resulting from SARS-CoV.

Abstract: The present invention pertains to antigenic peptides of SARS-CoV and their use in diagnostic test methods and in the treatment of condition resulting from SARS-CoV. Furthermore, this invention provides antibodies capable of specifically recognizing the peptides of the invention. The antibodies can also advantageously be used in diagnostic test methods and in the treatment of conditions resulting from SARS-CoV.

Abstract: The present invention pertains to antigenic peptides of SARS-CoV and their use in diagnostic test methods and in the treatment of condition resulting from SRAS-CoV. Furthermore, this invention provides antibodies capable of specifically recognizing the peptides of the invention. The antibodies can also advantageously be used in diagnostic test methods and in the treatment of condition resulting from SRAS-CoV.

Abstract: The invention relates to the field of candidate drug testing and drug development. A method is provided for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule capable of reacting with the at least first and second reactive group; contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the at least one molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage, preferably wherein the coupling reaction is performed in solution, more preferably in an aqueous solution. Furthermore, a method is provided for selecting a candidate drug compound comprising providing a library of compounds according to the invention and determining the binding of a target molecule to the compounds.

Abstract: An electronic data processing device, comprising an access protected memory, provided for storing secure data and a data processing member, provided for processing said secure data, said terminal comprises a tampering detection and protection circuit provided for detecting a tamper condition and for generating a tamper signal upon detection of said tamper condition, said tampering detection and protection circuit being connected to a tampering sequencer, provided for disabling said processing member upon receipt of said tampering signal, said memory comprises a security register provided for storing keys for encrypting said secure data and a memory section provided for storing keys for encrypting said secure data and a memory section provided for temporarily storing secure data processed by said data processing member, said tampering sequencer comprises an internal clock generator provided for generating, upon receipt of said tamper signal a tamper pulse and a series of clock pulses, said tampering sequencer

Abstract: A method and a device for reading out keys of a keyboard. The read-out is realised by randomly generating a scanning pattern comprising for each row and column a read-out value to be applied on the rows and columns. The scanning pattern is preferably changed after having been applied to the keys. After application of the randomly generated pattern, the verification routine is applied in order to identify the selected keys.

Abstract: An electronic data processing device, comprising an access protected memory, provided for storing secure data and a data processing member, provided for processing said secure data, said terminal comprises a tampering detection and protection circuit provided for detecting a tamper condition and for generating a tamper signal upon detection of said tamper condition, said tampering detection and protection circuit being connected to a tampering sequencer, provided for disabling said processing member upon receipt of said tampering signal, said memory comprises a security register provided for storing keys for encrypting said secure data and a memory section provided for storing keys for encrypting said secure data and a memory section provided for temporarily storing secure data processed by said data processing member, said tampering sequencer comprises an internal clock generator provided for generating, upon receipt of said tamper signal a tamper pulse and a series of clock pulses, said tampering sequencer

Abstract: The invention is directed to an anion-complexing compound with the formula I wherein R1 is a six-membered ring, Y′ is —NHC(X)NH—, and Y″ is selected from the group consisting of —NHC(X′)—, —C(X′)NH—, and —NHC(X′) NH—; and wherein X and X′, independently of one another, is a sulphur or oxygen atom. R4 and R4′ are either identical represented by a variety of groups or together represent a group such that the compound has a macrocyclic structure. The invention is also directed to a method of preparing such a compound, an ion-selective membrane, as well as a sensor provided with such a compound or membrane.