Patents by Inventor Peter Valent

Peter Valent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10383955
    Abstract: The present invention relates to a human mast cell line corresponding to deposit number CNCM I-4551 and also to the lines derived therefrom, in particular the derived lines corresponding respectively to deposit numbers CNCM I-4552 and CNCM I-4553, and to the uses thereof, in particular for screening for compounds of therapeutic interest.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: August 20, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE DE CACHAN, MEDIZINISCHE UNIVERSITAT WIEN
    Inventors: Michel Arock, Peter Valent, Rosine Saleh, Ghaith Wedeh, Christian Auclair
  • Patent number: 9963489
    Abstract: An immobilized polypeptide including a polypeptide bound to a surface of a polypeptide array or a chip, wherein the polypeptide has the amino acid sequence of SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:1 lacking the N-terminal methionine, SEQ ID NO:3 lacking the N-terminal methionine, or a combination thereof.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: May 8, 2018
    Assignee: BIOMAY AG
    Inventors: Rudolf Valenta, Margit Weghofer, Susanne Vrtala, Friedrich Horak, Peter Valent, Stefan Florian
  • Publication number: 20180022808
    Abstract: The present invention relates to an antibody construct comprising at least one antigen binding site specific for ICAM1 and at least one antigen binding site specific for at least one allergen.
    Type: Application
    Filed: February 10, 2016
    Publication date: January 25, 2018
    Inventors: Christoph Madritsch, Sabine Flicker, Rudolf Valenta, Elisabeth Gader-Maier, Julia Eckl-Dorna, Verena Niederberger, Katharina Blatt, Peter Valent, Isabella Ellinger
  • Publication number: 20170218034
    Abstract: An immobilized polypeptide including a polypeptide bound to a surface of a polypeptide array or a chip, wherein the polypeptide has the amino acid sequence of SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:1 lacking the N-terminal methionine, SEQ ID NO:3 lacking the N-terminal methionine, or a combination thereof.
    Type: Application
    Filed: December 16, 2016
    Publication date: August 3, 2017
    Applicant: Biomay AG
    Inventors: Rudolf VALENTA, Margit Weghofer, Susanne Vrtala, Friedrich Horak, Peter Valent, Stefan Florian
  • Patent number: 9296828
    Abstract: The present invention relates to a hypoallergenic protein consisting of at least one hypoallergenic molecule derived from an allergen, which is fused or conjugated to at least one second non-allergenic protein or fragment thereof.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: March 29, 2016
    Assignee: BIOMAY AG
    Inventors: Rudolf Valenta, Margarete Focke-Tejkl, Birgit Linhart, Susanne Vrtala, Peter Valent, Renate Reininger, Susanne Spitzauer, Ines Swoboda, Marianne Van Hage, Hans Grönlund, Johanna Tinhofer, Kerstin Westritschnig, Theresia Popow-Kraupp
  • Patent number: 9103835
    Abstract: The present invention relates to a method for identifying hypoallergenic polypeptides and to a corresponding screening method. The invention further relates to hypoallergenic polypeptides identified by the method of the invention and to the prophylactic and therapeutic use of these polypeptides.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: August 11, 2015
    Assignee: BIOMAY AG
    Inventors: Rudolf Valenta, Birgit Linhart, Margarete Focke-Tejkl, Angela Neubauer, Peter Valent, Katharina Blatt
  • Patent number: 9086238
    Abstract: The present invention provides a biomass dryer/burner unit having an air cleaning apparatus adapted to accept emissions from unit and to convert said emissions to clean air to meet government emission standards. The air cleaning apparatus including a spray scrubber fluidly connected to the unit adapted to moisten emissions, a recirculation tank in fluid communication with a collection tank, angled baffle plates, and the collection tank further having a sensor adapted to measure contaminant levels contained within the recirculation air filtration system. If the air contained within the collection tank measures above a predetermined contaminant level, then the air contained within the collection tank is directed back into the spray scrubber. If the air contained within the collection tank is below a predetermined level, then the air is exhausted into the atmosphere. Water is further allowed to recirculate back to the spray scrubber.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 21, 2015
    Inventor: Peter Valente
  • Publication number: 20150104458
    Abstract: A polypeptide containing an amino acid sequence having at least 60% identity to the amino acid sequence SEQ ID No. 1 or containing at least one amino acid fragment of at least 6 consecutive amino acid residues of the amino acid sequence SEQ ID No. 1 or having immunological cross-reactivity to the amino acid sequence SEQ ID No. 1 or fragments thereof, wherein the amino acid sequence SEQ ID No. 1 codes for an allergen and the polypeptide comprises at least one T cell epitope recognized by a T cell receptor specific for a molecule having the amino acid sequence SEQ ID No. 1.
    Type: Application
    Filed: August 26, 2014
    Publication date: April 16, 2015
    Applicant: Biomay AG
    Inventors: Rudolf VALENTA, Margit Weghofer, Susanne Vrtala, Friedrich Horak, Peter Valent, Stefan Florian
  • Publication number: 20140298497
    Abstract: The present invention relates to a human mast cell line corresponding to deposit number CNCM I-4551 and also to the lines derived therefrom, in particular the derived lines corresponding respectively to deposit numbers CNCM I-4552 and CNCM I-4553, and to the uses thereof, in particular for screening for compounds of therapeutic interest.
    Type: Application
    Filed: November 2, 2012
    Publication date: October 2, 2014
    Inventors: Michel Arock, Peter Valent, Rosine Saleh, Ghaith Wedeh, Christian Auclair
  • Publication number: 20140121356
    Abstract: The present invention relates to non-naturally occurring polypeptides derived from fish allergens such as parvalbumin Cyp c 1.01 from carp. The polypeptides display reduced allergenic activity and are useful as allergy vaccines for treatment of sensitized allergic patients and for prophylactic vaccination.
    Type: Application
    Filed: December 20, 2013
    Publication date: May 1, 2014
    Applicant: BIOMAY PRODUKTIONS- UND HANDELS-AKTIENGESELLSCHAFT
    Inventors: Rudolf VALENTA, Peter Valent, Susanne Spitzauer, Ines Swoboda
  • Patent number: 8709435
    Abstract: Hypoallergenic mosaic antigens assembled from naturally-occurring allergens are disclosed herein. Also disclosed are methods of making such hypoallergenic mosaic antigens, particularly those derived from plant allergens such as timothy grass pollen (Phl p 1 and Phl p 2) and birch pollen (Bet v 1). In a particularly preferred embodiment, the method of making the hypoallergenic mosaic antigen involves the steps of (a) cleaving a naturally-occurring allergen into at least two, preferably at least three non-overlapping peptide fragments and (b) recombining the peptide fragments such that the mosaic antigen includes all or substantially all of the amino acids of the original naturally-occurring allergen, though in a different order.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: April 29, 2014
    Assignee: Biomay AG
    Inventors: Raffaela Campana, Rudolf Valenta, Susanne Vrtala, Ines Swoboda, Margarete Focke-Tejkl, Anna Gieras, Susanne Spitzauer, Peter Valent, Katharina Blatt, Birgit Linhart, Dietrich Kraft
  • Publication number: 20130206572
    Abstract: The present invention provides a biomass dryer/burner unit having an air cleaning apparatus adapted to accept emissions from unit and to convert said emissions to clean air to meet government emission standards. The air cleaning apparatus including a spray scrubber fluidly connected to the unit adapted to moisten emissions, a recirculation tank in fluid communication with a collection tank, angled baffle plates, and the collection tank further having a sensor adapted to measure contaminant levels contained within the recirculation air filtration system. If the air contained within the collection tank measures above a predetermined contaminant level, then the air contained within the collection tank is directed back into the spray scrubber. If the air contained within the collection tank is below a predetermined level, then the air is exhausted into the atmosphere. Water is further allowed to recirculate back to the spray scrubber.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 15, 2013
    Inventor: Peter Valente
  • Patent number: 8475564
    Abstract: The present invention provides a biomass dryer/burner having an air cleaning apparatus adapted to accept emissions from the biomass dryer/burner and to convert said emissions to clean air to meet government emission standards. The biomass dryer/burner unit includes a dryer adapted to dry biomass, such as demolition waste or cut trees. The biomass dryer/burner unit optionally including a burner adapted to burn biomass. The biomass dryer/burner further producing emissions requiring cleaning before exhausting to the atmosphere. The air cleaning apparatus including a spray scrubber fluidly connected to the biomass dryer/burner adapted to moisten emissions, a recirculation tank in fluid communication with a collection tank, and the recirculation tank further having a sensor adapted to measure contaminant levels contained within the recirculation air filtration system. The sensor contained within the recirculation tank measures levels of carbon monoxide.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: July 2, 2013
    Inventor: Peter Valente
  • Patent number: 8440200
    Abstract: Methods for desensitization of a mammal suffering from IgE mediated allergy comprise the steps of: administering to said mammal a therapeutically effective amount of an immunogenic and hypoallergenic composition which comprises (i) a Phl p 6 molecule having an N-terminal truncation which makes the molecule at least lack IgE binding capacity, and/or (ii) a Phl p 6 molecule having a C-terminal truncation which makes the molecule at least lack IgE binding capacity, wherein the molecules of (i) and (ii), if employed in combination, together span the complete sequence of Phl p 6, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: May 14, 2013
    Assignee: Phadia AB
    Inventors: Rudolf Valenta, Susanne Vrtala, Sabine Stumvoll, Hans Grönlund, Monika Grote, Luca Vangelista, Annalisa Pastore, Wolfgang R. Sperr, Peter Valent, Dietrich Kraft
  • Publication number: 20120207788
    Abstract: The present invention relates to a method for identifying hypoallergenic polypeptides and to a corresponding screening method. The invention further relates to hypoallergenic polypeptides identified by the method of the invention and to the prophylactic and therapeutic use of these polypeptides.
    Type: Application
    Filed: September 9, 2010
    Publication date: August 16, 2012
    Applicant: BIOMAY AG
    Inventors: Rudolf Valenta, Birgit Linhart, Margarete Focke-Tejkl, Angela Neubauer, Peter Valent, Katharina Blatt
  • Publication number: 20120009210
    Abstract: Hypoallergenic mosaic antigens assembled from naturally-occurring allergens are disclosed herein. Also disclosed are methods of making such hypoallergenic mosaic antigens, particularly those derived from plant allergens such as timothy grass pollen (Phl p 1 and Phl p 2) and birch pollen (Bet v 1). In a particularly preferred embodiment, the method of making the hypoallergenic mosaic antigen involves the steps of (a) cleaving a naturally-occurring allergen into at least two, preferably at least three non-overlapping peptide fragments and (b) recombining the peptide fragments such that the mosaic antigen includes all or substantially all of the amino acids of the original naturally-occurring allergen, though in a different order.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 12, 2012
    Applicant: BIOMAY AG
    Inventors: Raffaela Campana, Rudolf Valenta, Susanne Vrtala, Ines Swoboda, Anna Gieras, Susanne Spitzauer, Peter Valent, Katharina Blatt, Margarete Focke-Tejkl, Birgit Linhart, Dietrich Kraft
  • Patent number: 8076321
    Abstract: The present invention relates to the use of the combination of tyrosine phosphate inhibitors AMN107 and PKC412 for the preparation of a drug for the treatment of a mast cell-related proliferative disease. The present invention is also drawn to a combination treatment of a tyrosine phosphate inhibitor and a TK-inhibitor that is effective against a mast cell-related proliferative disease, including especially systemic mastocytosis (SM) including aggressive SM (ASM) and mast cell leukemia (MCL).
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: December 13, 2011
    Inventor: Peter Valent
  • Publication number: 20100216717
    Abstract: The present invention relates to non-naturally occurring polypeptides derived from fish allergens such as parvalbumin Cyp c 1.01 from carp. The polypeptides display reduced allergenic activity and are useful as allergy vaccines for treatment of sensitized allergic patients and for prophylactic vaccination.
    Type: Application
    Filed: March 10, 2010
    Publication date: August 26, 2010
    Inventors: Rudolf Valenta, Peter Valent, Susanne Spitzauer, Ines Swoboda
  • Publication number: 20100202949
    Abstract: The present invention provides a biomass dryer/burner having an air cleaning apparatus adapted to accept emissions from the biomass dryer/burner and to convert said emissions to clean air to meet government emission standards. The biomass dryer/burner unit includes a dryer adapted to dry biomass, such as demolition waste or cut trees. The biomass dryer/burner unit optionally including a burner adapted to burn biomass. The biomass dryer/burner further producing emissions requiring cleaning before exhausting to the atmosphere. The air cleaning apparatus including a spray scrubber fluidly connected to the biomass dryer/burner adapted to moisten emissions, a recirculation tank in fluid communication with a collection tank, and the recirculation tank further having a sensor adapted to measure contaminant levels contained within the recirculation air filtration system. The sensor contained within the recirculation tank measures levels of carbon monoxide.
    Type: Application
    Filed: February 8, 2010
    Publication date: August 12, 2010
    Inventor: Peter Valente
  • Patent number: RE42324
    Abstract: The present invention relates to a novel drug candidate having a potential for universal therapy of allergy and asthma. The invention provides a Fab (antibody fragment), having the following characteristics: a) inhibits the IgE-Fc?RI interaction; b) binds to free and cell-bound IgE; and c) is non-anaphylactic.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: May 3, 2011
    Assignee: Phadia AB
    Inventors: Sylvia Laffer, Erik Hogbom, Kenneth H. Roux, Jonas Adriansson, Wolfgang R. Sperr, Peter Valent, Dietrich Kraft, Hans Grönlund, Rudolf Valenta