Patents by Inventor Peter Verheesen
Peter Verheesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170295781Abstract: Described is the specific delivery of agrochemicals to plants. More specifically, a targeting agent has at least one binding domain that specifically binds to a binding site on an intact living plant. Such binding domains include a peptide having 4 framework regions and 3 complementary determining regions, or fragment(s) thereof, wherein the binding domains bind or retain a carrier onto a plant. Described are binding domains that specifically bind trichomes, stomata, cuticle, lenticels, thorns, spines, root hairs, or wax layer. Further described are methods for delivering agrochemicals to a plant, for depositing agrochemicals on a plant, and for retaining the agrochemicals on a plant, using targeting agents comprising the binding domains, and to methods for protecting a plant against stress or controlling plant growth. Also, described are methods for manufacturing a specifically targeting agrochemical carrier.Type: ApplicationFiled: April 17, 2017Publication date: October 19, 2017Applicant: AGROSAVFE N.V.Inventors: Erik Jongedijk, Peter Verheesen
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Patent number: 9516879Abstract: Described is an antigen-binding protein, preferably comprising an amino acid sequence that comprises four framework regions and three complementarity-determining regions, wherein the antigen-binding protein is capable of binding a chitinous polysaccharide, and uses thereof.Type: GrantFiled: August 26, 2011Date of Patent: December 13, 2016Assignee: Agrosavfe N.V.Inventors: Peter Verheesen, Chris De Jonghe, Erik Jongedijk
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Publication number: 20160289327Abstract: The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.Type: ApplicationFiled: February 23, 2016Publication date: October 6, 2016Applicant: Ablynx N.V.Inventors: Guy Hermans, Peter Verheesen, Edward Dolk, Hendricus Renerus Jacobus Mattheus Hoogenboom, Michael John Scott Saunders, Hans De Haard, Renee de Bruin
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Publication number: 20160280786Abstract: The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.Type: ApplicationFiled: February 23, 2016Publication date: September 29, 2016Applicant: Ablynx N.V.Inventors: Guy Hermans, Peter Verheesen, Edward Dolk, Hendricus Renerus Jacobus Mattheus Hoogenboom, Michael John Scott Saunders, Hans De Haard, Renee de Bruin
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Patent number: 9380781Abstract: Described is a composition for seed treatment comprising a plant seed-binding protein, preferably an antigen-binding plant seed-binding protein. In one embodiment, the seed-binding protein is binding a polysaccharide, preferably pectin. Further described is the use of a plant seed-binding protein to bind a plant-enhancing agent to a plant seed, and to a method for treating plant seeds.Type: GrantFiled: August 26, 2011Date of Patent: July 5, 2016Assignee: Agrosavfe N.V.Inventors: Peter Verheesen, Chris De Jonghe, Erik Jongedijk
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Publication number: 20160145325Abstract: The present invention relates to agrochemical and biological control compositions for combating pests, more specifically plant pests, comprising at least one heavy chain variable domain of an antibody, which specifically binds to a sphingolipid of a plant pathogen. The invention further provides methods for protecting or treating a plant or a part of a plant from an infection or other biological interaction with a plant pathogen, at least comprising the step of applying directly or indirectly to a plant or to a part of a plant, an agrochemical composition, under conditions effective to protect or treat a plant or a part of a plant against a infection or biological interaction with a plant pathogen.Type: ApplicationFiled: April 29, 2014Publication date: May 26, 2016Applicant: AGROSAVFE N.V.Inventors: Peter Verheesen, Chris De Jonghe, Inge Elodie Van Daele, Miguel Francesco Coleta De Bolle, João Filipe Veloso Vieira, Karin Thevissen, Bruno Cammue
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Publication number: 20160075769Abstract: The present invention relates to agrochemical and biological control compositions for combating pests, more specifically plant pests, comprising at least one polypeptide, which specifically binds to a pest. The invention further provides methods for protecting or treating a plant or a part of a plant from an infection or other biological interaction with a plant pathogen, at least comprising the step of applying directly or indirectly to a plant or to a part of a plant, an agrochemical composition, under conditions effective to protect or treat a plant or a part of a plant against a infection or biological interaction with a plant pathogen. Further provided are methods for producing such agrochemical compositions and formulations, to polypeptides with a specific pesticidal activity comprised within an agrochemical formulation, to nucleic acids encoding such polypeptide and to plants comprising chimeric genes comprising such nucleic acids.Type: ApplicationFiled: April 29, 2014Publication date: March 17, 2016Inventors: Peter Verheesen, Chris De Jonghe, Inge Elodie Van Daele, Miguel Francesco Coleta De Bolle, João Filipe Veloso Vieira, Karin Thevissen, Bruno Cammue
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Publication number: 20150299327Abstract: The present invention relates to amino acid sequences that are directed against (as defined herein) human cellular receptors for viruses and/or bacteria such as e.g. Nanobodies specifically recognizing hCD4, hCXCR4, hCCR5, hTLR4, human alphaV integrin, human beta3 integrin, human beta1 integrin, human alpha2 integrin, hCD81, hSR-BI, hClaudin-1, hClaudin-6 and hClaudin-9, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. Said amino acid sequences may be used to prevent human cell entry of HIV, HCV, adenoviruses, hantavirus, herpesvirus, echo-virus 1 and others.Type: ApplicationFiled: February 20, 2015Publication date: October 22, 2015Applicant: Ablynx N.V.Inventors: Christophe Blanchetot, Martine Smit, Regorius Leurs, Sven Jähnichen, Dominique Schols, Michael John Scott Saunders, Johannes Joseph Wilhelmus De Haard, Peter Vanlandschoot, Peter Verheesen
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Publication number: 20150266958Abstract: The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.Type: ApplicationFiled: October 30, 2014Publication date: September 24, 2015Applicant: Ablynx N.V.Inventors: Guy Hermans, Peter Verheesen, Edward Dolk, Hendricus Renerus Jacobus Mattheus Hoogenboom, Michael John Scott Saunders, Hans De Haard, Renee de Bruin
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Patent number: 9005963Abstract: The present invention relates to amino acid sequences that are directed against (as defined herein) human cellular receptors for viruses and/or bacteria such as e.g. NANOBODIES specifically recognizing hCD4, hCXCR4, hCCR5, hTLR4, human alphaV integrin, human beta3 integrin, human beta1 integrin, human alpha2 integrin, hCD81, hSR-BI, hClaudin-1, hClaudin-6 and hClaudin-9, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences may be used to prevent human cell entry of HIV, HCV, adenoviruses, hantavirus, herpesvirus, echo-virus 1 and others.Type: GrantFiled: October 14, 2009Date of Patent: April 14, 2015Assignee: Ablynx N.V.Inventors: Christophe Blanchetot, Martine Smit, Regorius Leurs, Sven Jähnichen, Dominique Schols, Michael John Scott Saunders, Johannes Joseph Wilhelmus De Haard, Peter Vanlandschoot, Peter Verheesen
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Publication number: 20150087517Abstract: The present disclosure relates to the manufacturing of specifically targeting microcapsules comprising agrochemicals. More specifically, the disclosure relates to specifically targeting microcapsules, to which targeting agents are covalently linked at a ratio from about 0.01 ?g-to about 1 ?g targeting agents per square centimeter of the surface of the microcapsule, such that the microcapsules are capable of binding the agrochemicals contained in the microcapsules to a surface, and to agrochemical compositions comprising such microcapsules.Type: ApplicationFiled: October 8, 2012Publication date: March 26, 2015Inventors: Peter Verheesen, Chris De Jonghe
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Patent number: 8907065Abstract: The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.Type: GrantFiled: December 17, 2007Date of Patent: December 9, 2014Assignee: Ablynx N.V.Inventors: Guy Hermans, Peter Verheesen, Edward Dolk, Hendricus Renerus Jacobus Mattheus Hoogenboom, Michael John Scott Saunders, Johannes Joseph Wilhelmus De Haard, Renee de Bruin
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Publication number: 20140128579Abstract: Described is the specific delivery of agrochemicals to plants. More specifically, a targeting agent has at least one binding domain that specifically binds to a binding site on an intact living plant. Such binding domains include a peptide having 4 framework regions and 3 complementary determining regions, or fragment(s) thereof, wherein the binding domains bind or retain a carrier onto a plant. Described are binding domains that specifically bind trichomes, stomata, cuticle, lenticels, thorns, spines, root hairs, or wax layer. Further described are methods for delivering agrochemicals to a plant, for depositing agrochemicals on a plant, and for retaining the agrochemicals on a plant, using targeting agents comprising the binding domains, and to methods for protecting a plant against stress or controlling plant growth. Also, described are methods for manufacturing a specifically targeting agrochemical carrier.Type: ApplicationFiled: September 4, 2013Publication date: May 8, 2014Applicant: AGROSAVFE N.V.Inventors: Erik Jongedijk, Peter Verheesen
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Patent number: 8598081Abstract: Described is the specific delivery of agrochemicals to plants. More specifically, a targeting agent has at least one binding domain that specifically binds to a binding site on an intact living plant. Such binding domains include a peptide having 4 framework regions and 3 complementarity-determining regions, or fragment thereof, wherein the binding domains bind or retain a carrier onto a plant. Described are binding domains that specifically bind trichomes, stomata, cuticle, lenticels, thorns, spines, root hairs, or wax layer. Further described is a method for delivering agrochemicals to a plant, for depositing agrochemicals on a plant, and for retaining the agrochemicals on a plant, using targeting agents comprising the binding domains, and to a method for protecting a plant against stress or controlling plant growth. Also, described is a method for manufacturing a specifically targeting agrochemical carrier.Type: GrantFiled: April 6, 2011Date of Patent: December 3, 2013Assignee: AgroSavfe N.V.Inventors: Erik Jongedijk, Peter Verheesen
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Publication number: 20130227747Abstract: Described is an antigen-binding protein, preferably comprising an amino acid sequence that comprises four framework regions and three complementarity-determining regions, wherein the antigen-binding protein is capable of binding a chitinous polysaccharide, and uses thereof.Type: ApplicationFiled: August 26, 2011Publication date: August 29, 2013Inventors: Peter Verheesen, Chris De Jonghe, Erik Jongedijk
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Publication number: 20130224226Abstract: Described is a binding domain, preferably an antigen binding domain, more preferably an antigen binding domain that specifically binds a binding site on an insect. More specifically, described are antigen binding domains comprising an amino acid sequence that comprises 4 framework regions and 3 complementary determining regions, whereby the antigen binding domains are capable to bind specifically to an insect as a whole, preferably to a binding site on the insect surface. Further described is the use of the binding domain to deliver a compound, preferably a biologically active agent to the insect, and to insecticidal compositions comprising the binding domain.Type: ApplicationFiled: August 25, 2011Publication date: August 29, 2013Applicant: AGROSAVFE N.V.Inventors: Peter Verheesen, Erik Jongedijk
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Publication number: 20130225403Abstract: Described is a composition for seed treatment comprising a plant seed-binding protein, preferably an antigen-binding plant seed-binding protein. In one embodiment, the seed-binding protein is binding a polysaccharide, preferably pectin. Further described is the use of a plant seed-binding protein to bind a plant-enhancing agent to a plant seed, and to a method for treating plant seeds.Type: ApplicationFiled: August 26, 2011Publication date: August 29, 2013Inventors: Peter Verheesen, Chris De Jonghe, Erik Jongedijk
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Publication number: 20120253008Abstract: The present invention relates to amino acid sequences that are capable of binding to serum proteins; to compounds, proteins, polypeptides, fusion proteins or constructs comprising or essentially consisting of such amino acid sequences; to nucleic acids that encode such amino acid sequences, compounds, proteins, polypeptides, fusion proteins or constructs; to compositions, and in particular pharmaceutical compositions, that comprise such amino acid sequences, compounds, proteins, polypeptides, fusion proteins or constructs; and to uses of such amino acid sequences, compounds, proteins, polypeptides, fusion proteins or constructs.Type: ApplicationFiled: June 13, 2012Publication date: October 4, 2012Applicant: Ablynx N.V.Inventors: Hilde Adi Pierrette Revets, Carlo Boutton, Stephanie Staelens, Peter Verheesen
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Patent number: 8217140Abstract: The present invention relates to amino acid sequences that are capable of binding to serum proteins; to compounds, proteins, polypeptides, fusion proteins or constructs comprising or essentially consisting of such amino acid sequences; to nucleic acids that encode such amino acid sequences, compounds, proteins, polypeptides, fusion proteins or constructs; to compositions, and in particular pharmaceutical compositions, that comprise such amino acid sequences, compounds, proteins, polypeptides, fusion proteins or constructs; and to uses of such amino acid sequences, compounds, proteins, polypeptides, fusion proteins or constructs.Type: GrantFiled: April 16, 2009Date of Patent: July 10, 2012Assignee: Ablynx N.V.Inventors: Hilde Adi Pierrette Revets, Carlo Boutton, Stephanie Staelens, Peter Verheesen
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Publication number: 20110318347Abstract: The present invention relates to amino acid sequences that are directed against (as defined herein) human cellular receptors for viruses and/or bacteria such as e.g. Nanobodies specifically recognizing hCD4, hCXCR4, hCCR5. hTLR4, human alphaV integrin, human beta3 integrin, human beta1 integrin, human alpha2 integrin, hCD81, hSR-B1, hClaudin-1, hClaudin-6 and hClaudin-9, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. Said amino acid sequences may be used to prevent human cell entry of HIV, HCV, adenoviruses, hantavirus, herpesvirus, echo-virus 1 and others.Type: ApplicationFiled: October 14, 2009Publication date: December 29, 2011Applicant: Ablynx N.V.Inventors: Christophe Blanchetot, Martine Smit, Regorius Leurs, Sven Jähnichen, Dominique Schols, Michael John Scott Saunders, Johannes Josephn Wilhelmus De Haard, Peter Vanlandschoot, Peter Verheesen