Abstract: The present invention is concerned with a hand pipette with a piston arrangement which is forced upwardly by an elastic force, the piston of which is displaceable in a removable pipette tip and the piston rod of which can be displaced downwardly against the elastic force by external operation to such an extent that the piston, at the lower end of the piston stroke, is at the lower end of the pipette tip, the lower end of the pipette being provided with a holding ring through which the piston rod passes and which carries the removable pipette tip at the bottom of the holding ring and at the top is mounted so as to be axially displaceable and lockable.