Patents by Inventor Peter W. Stacpoole

Peter W. Stacpoole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, assays, and kits related to dichloroacetate (DCA)
    Patent number: 9765393
    Abstract: Embodiments of the present disclosure provide for methods, assays, and kits for predicting dosing for subjects. In addition, embodiments of the present disclosure include methods, assays, and kits, of determining if a patient can effectively metabolize one or both of phenylalanine and tryrosine.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: September 19, 2017
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Taimour Langaee, Peter W. Stacpoole
  • METHODS, ASSAYS, AND KITS RELATED TO DICHLOROACETATE (DCA)
    Publication number: 20130090382
    Abstract: Embodiments of the present disclosure provide for methods, assays, and kits for predicting dosing for subjects. In addition, embodiments of the present disclosure include methods, assays, and kits, of determining if a patient can effectively metabolize one or both of phenylalanine and tryrosine.
    Type: Application
    Filed: June 14, 2011
    Publication date: April 11, 2013
    Inventors: Taimour Langaee, Peter W. Stacpoole
  • Compositions comprising carbonate/bicarbonate buffered dichloroacetic acid and methods for treatment of metabolic and cardiovascular disorders
    Patent number: 5643951
    Abstract: Methods for the treatment of metabolic and/or cardiovascular disorders comprising administering to a human in need thereof a therapeutically effective amount of a composition comprising dichloroacetic acid or a pharmaceutically acceptable salt or derivative thereof and a pharmaceutically acceptable mixture of carbonate and bicarbonate ions, the weight ratio of dichloroacetic acid, derivative or salt thereof to the mixture of carbonate and bicarbonate ions being in the range of from about 100:1 to about 0.01:1.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 1, 1997
    Inventors: Peter W. Stacpoole, Robert M. Bersin
  • Certain inositol-nicotinate ester derivatives and polyionic complexes therefore useful for treating diabetes meuitus, hyperlipidemia and lactic acidosis
    Patent number: 4801597
    Abstract: The present invention relates to pharmaceutical compositions and methods for the treatment of metabolic disorders and to certain inositol-nicotinate dichloroacetate derivatives as the active ingredients therein.
    Type: Grant
    Filed: June 11, 1985
    Date of Patent: January 31, 1989
    Assignee: University of Florida
    Inventors: Peter W. Stacpoole, Nicholas S. Bodor
  • Treatment of metabolic disorders with dichloroacetate-thiamine preparations
    Patent number: 4558050
    Abstract: Chemical compounds useful in the treatment of metabolic disorders comprising the reaction product of thiamine and a dichloroacetic acid.
    Type: Grant
    Filed: March 1, 1984
    Date of Patent: December 10, 1985
    Assignee: University of Florida
    Inventor: Peter W. Stacpoole
  • Treatment of hyperlipoproteinemia with a dichloroacetate salt
    Patent number: 4122188
    Abstract: The present invention relates to the use of salts of dichloroacetate which contain one or two molecules of dichloroacetate and one or two atoms of a mono- or divalent metallic cation, and particularly sodium dichloroacetate, for the treatment of hyperlipoproteinemia in humans.The method of this invention has utility in the treatment of conditions in a human patient-subject in which there is abnormal elevation of the blood levels of one or more of the major lipids (cholesterol and triglycerides) normally present in the body.
    Type: Grant
    Filed: August 29, 1977
    Date of Patent: October 24, 1978
    Assignee: Vanderbilt University
    Inventor: Peter W. Stacpoole