Abstract: Methods and systems are provided for generating a treatment plan for arch expansion where a polymeric shell appliance is utilized to generate one or more activation forces that facilitate tooth movement. The polymeric shell appliances may comprise one or more tooth receiving cavities, in which each of the plurality of tooth receiving cavities is shaped and arranged to provide a counter moment of each of the plurality of teeth.

Abstract: A improved method of additive manufacturing of a recycled granulate is provided. The method comprises providing a starting article. A shredder shreds the starting article to give a shredded product. A granulator shreds the shredded product to give a recycled granulate. The recycled granulate is fed into an additive manufacturing machine. The additive manufacturing machine prints a printed article using the recycled granulate. The method does not comprise a step of compounding the recycled granulate using a twin screw extruder. The starting article, the shredded product, and the recycle granulate each comprise a fiber reinforced polymer composite.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

Abstract: The present invention provides a composition comprising the compound having the structure: or a salt of the compound; 4-amino-2-[19F]-fluorobenzoic acid or a salt of 4-amino-2-[19F]-fluorobenzoic acid; and at least one acceptable carrier.

Abstract: Disclosed are monoclonal antibodies, antigen binding fragments, and bi-specific antibodies that specifically bind a coronavirus spike protein, such as SARS-CoV-2. Also disclosed is the use of these antibodies for inhibiting a coronavirus infection, such as a SARS-CoV-2 infection. In addition, disclosed are methods for detecting a coronavirus, such as SARS-CoV-2, in a biological sample, using the disclosed antibodies.

Abstract: The present invention relates to a heterophasic propylene copolymer polymerized the presence of a single-site catalyst with a low tensile modulus, a process for preparing such a heterophasic propylene copolymer and articles made therefrom.

Abstract: Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural and/or functional features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.

Abstract: A tool arrangement for forming a tunnel in a vertebra to perform nerve ablation includes a tamp having a distal end portion that includes a tip for creating the tunnel in the vertebra and a curvable portion to direct the tip along a curved path within the vertebra; a first cannula including a cannula body that is straight along an entire length of the cannula body and configured to receive the curvable portion of the tamp and straighten the curvable portion; and a tool hub including a stationary cannula attachment coupled to the first cannula and a movable head coupled to the tamp and configured to move toward or away from the stationary cannula attachment to extend or retract, respectively, the curvable portion of the tamp from or into, respectively, the first cannula.

Abstract: A radiofrequency frontend device includes a memory array, which includes a plurality of input lines; a plurality of output lines; and a plurality of impedance devices, each impedance device connecting an input line of the plurality of input lines to an output line of the plurality of output lines, wherein each impedance represents a filter coefficient; wherein the radiofrequency frontend device is configured to provide at each input line of the plurality of input lines a sampled voltage of an analog electric signal, each sampled voltage corresponding to a voltage of the analog electric signal during a respective time period of a plurality of time periods; and when the memory array receives the sampled voltages, the memory array is configured to modify each of the sampled voltages by a respective impedance device of the plurality of impedance devices and sum the modified sampled voltages.

Abstract: A method and system for estimating the ground state energy of a quantum Hamiltonian. The disclosed algorithm may run on any hardware and is suited for early fault tolerant quantum computers. The algorithm employs low-depth quantum circuits with one ancilla qubit with classical post-processing. The algorithm first draws samples from Hadamard tests in which the unitary is a controlled time evolution of the Hamiltonian. The samples are used for evaluating the convolution of the spectral measure and a filter function, and then inferring the ground state energy from this convolution. Quantum circuit depth is linear in the inverse spectral gap and poly-logarithmic in the inverse target accuracy and inverse initial overlap. Runtime is polynomial in the inverse spectral gap, inverse target accuracy, and inverse initial overlap. The algorithm produces a highly-accurate estimate of the ground state energy with reasonable runtime using low-depth quantum circuits.

Abstract: A method of operating an electrochromic device comprising: coupling a logic device to the electrochromic device; applying a voltage to the electrochromic device; receiving a current from the electrochromic device in response to the provided voltage; and with the logic device, determining an exact operating condition of the electrochromic device from the received current. A method of operating a plurality of electrochromic devices comprising: adjusting a frequency of voltage applied to the plurality of electrochromic devices, wherein each of the plurality of electrochromic devices is adjusted by a different frequency; measuring a duration of time required to change tint states of each of the electrochromic devices; and identifying a location of each of the plurality of electrochromic devices in response to the measured duration of time required to change the tint states of each of the electrochromic device.

Abstract: Polypropylene-based multilayer film, which is biaxially oriented, a process for manufacturing the biaxially oriented multilayer film and its use in flexible packaging.

Abstract: Film made from ethylene-propylene-1-butene terpolymer and propene-butene copolymer blend and ethylene-propylene-1-butene terpolymer and propene-butene copolymer blend.

Abstract: Methods and apparatuses for wireless communication for line-of-sight Multiple-Input-Multiple-Output (LOS MIMO) are described. A first pilot signal is transmitted to a second device. The first pilot signal is at least one of a constant phase pilot or a linear phase ramped pilot for estimating a misalignment of a second antenna array of the second device with respect to a first antenna array of the first device.

Abstract: Methods, systems, and devices for wireless communications at a device are described. The device may receive an indication of a configuration that schedules semi-persistently scheduled resources for transmissions from the first device. The device may also receive an indication of a set of resources available to the first device for requesting a set of the semi-persistently scheduled resources configured for the first device. The device may transmit a message over the set of resources to request the set of semi-persistently scheduled resources.

Abstract: The present invention discloses a high-temperature fluid transporting pipeline with a heat exchange apparatus installed therein, a suitable heat exchange apparatus and a heat exchange method, wherein heat contained in a high-temperature fluid can be recovered during the transportation thereof. The heat exchange apparatus comprises a heat exchange body inserted into the high-temperature fluid transporting pipeline, and a heat-receiving fluid coil installed therein. The method of heat exchange is that the high-temperature fluid heats an auxiliary fluid in a heat exchange cavity via a heat exchange panel of the heat exchange body in contact therewith, and the heated auxiliary fluid then conducts the heat to a heat-receiving fluid in the heat-receiving fluid coil.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Abstract: Data integrity checks for reducing communication latency is described. A transmitting endpoint transmits data to a receiving endpoint by generating an integrity tag for a first subset of data blocks and a second integrity tag for a second subset of data blocks. In implementations, the first and second integrity tags overlap at least one data block and are offset based on computational complexities of generating the integrity tags. A receiving endpoint generates comparison tags for each of the integrity tags and uses the comparison tags to validate an authenticity of received data. In response to validating the first and second integrity tags, data blocks covered by both the first and second integrity tags are released for use. Additional integrity tags are generated and validated for subsequent subsets of data blocks during data communication, thus reducing latency by offsetting times at which comparison tags are generated and validated.

Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

Abstract: A method of delivering optical energy to a substrate comprises applying a temporal group of optical pulses to a region of the substrate, wherein the temporal group comprises twenty or fewer pulses of a femtosecond pulse duration, arranged as a first subgroup of pulses comprising up to three pulses followed by a second subgroup of pulses comprising the remaining pulses in the temporal group; and wherein energies of the pulses are controlled such that pulses in the first subgroup have a first energy per pulse and pulses in a second subgroup of pulses have a second energy per pulse which is less than the first energy.