Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: Systems and methods for assessing the resilience of an infrastructural system. The system includes a computer program product stored on non-transitory machine-readable media. The media includes machine executable instructions for implementing a method for assessing the resilience of an infrastructural system. The method includes receiving, from an interface, scenario specific data regarding conditions for the infrastructural system; processing the scenario specific data to determine a vulnerability metric for a probability of failure for a component of the infrastructural system; determining, based on the vulnerability metric, an in-situ failure risk of the infrastructural system incorporating a complexity of environmental conditions; determining, based on the vulnerability metric, a recommended maintenance task for the component of the infrastructural system; and providing the in-situ failure risk of the infrastructural system and the recommended maintenance task for the component to the interface.

Abstract: A downhole tool has a pressure differential from one side of the tool to the other. The pressure differential is balanced across the actuating assembly and tool surfaces to minimize the force required to move a portion of the tool, such as a valve, between a first position to a second position, such as when opening or closing a downhole valve.

Abstract: The present invention relates to a downhole tool where a pressure differential exists from one side of the tool to the other. The pressure differential is balanced across the actuating assembly and tool surfaces to minimize the force required to move a portion of the tool, such as a valve, between a first position to a second position, such as when opening or closing a downhole valve.

Abstract: An arrangement of a genset and a container, in which the genset is arranged, whereby the arrangement also comprises a cooling device and the genset can be cooled in the operating state of the genset by the cooling device, whereby the cooling device is arranged between a first position in which the cooling device is arranged entirely within the container, and a second position in which at least part of the cooling device can be moved at least partially outside the container, whereby the genset can be moved into its operating state when the cooling device is in the second position.

Abstract: A system includes a cast mounting tower having an upper portion configured to support an engine, a generator, or any combination thereof and a plurality of ribs coupled to and supporting the upper portion of the mounting tower. The plurality of ribs extend from the upper portion in a direction crosswise to the upper portion, the upper portion and the plurality of ribs are integrally coupled as a one-piece structure of the cast mounting tower, and the cast mounting tower is configured to couple to a frame.

Abstract: A system includes a rotational coupling including a first rotational joint, a second rotational joint, and a coupling body disposed between the first and second rotational joints. The coupling body includes first and second body portions disposed about a rotational axis, and a layered portion disposed about the rotational axis radially between the first and second body portions. The layered portion includes first and second elastomeric portions disposed about the rotational axis, and a rigid portion disposed about the rotational axis radially between the first and second elastomeric portions. The rigid portion includes a plurality of radial protrusions.

Abstract: A system includes a rotational coupling including a first rotational joint, a second rotational joint, and a coupling body disposed between the first and second rotational joints. The coupling body includes first and second body portions disposed about a rotational axis, and a layered portion disposed about the rotational axis radially between the first and second body portions. The layered portion includes first and second elastomeric portions disposed about the rotational axis, and a rigid portion disposed about the rotational axis radially between the first and second elastomeric portions. The rigid portion includes a plurality of radial protrusions.

Abstract: A system includes a cast mounting tower having an upper portion configured to support an engine, a generator, or any combination thereof and a plurality of ribs coupled to and supporting the upper portion of the mounting tower. The plurality of ribs extend from the upper portion in a direction crosswise to the upper portion, the upper portion and the plurality of ribs are integrally coupled as a one-piece structure of the cast mounting tower, and the cast mounting tower is configured to couple to a frame.

Abstract: A fluid injection device (18) for controlling injection of fluid into an oil-carrying tube in an oil well includes an inlet (20) for receiving the fluid; an outlet (28) for supplying the fluid for injection into the oil-carrying tube; an inlet valve (22) in a fluid path between the inlet and the outlet; an actuator (24) for opening and closing the valve; and a connector (36) for coupling the inlet to a fluid supply tube (32) extending between the device and a source of the fluid above the ground. A method of controlling injection of fluid using such a device is also provided.

Abstract: A fluid injection device (38) for deployment in a well-bore to control injection of fluid into an oil reservoir, wherein the well-bore has an outer pipe (16) and an inner tube (14) which extends within the outer pipe and is connected at one end to a pressurized fluid supply above the ground. The device includes a control valve arrangement comprising: an inlet (42) for receiving the fluid from the inner tube; an outlet (56) for outputting the fluid outside the inner tube; an inlet valve (44) in a fluid path between the inlet and the outlet; and an actuator (50) associated with the inlet valve which is controllable to switch the inlet valve between its open and closed configurations, such that when the inlet valve is open, the fluid flows from the inner tube, via the inlet, fluid path and outlet to outside the inner tube. A method of controlling injection of fluid into an oil reservoir from a well-bore using such a device is also provided.

Abstract: A fluid injection device (18) for controlling injection of fluid into an oil-carrying tube in an oil well includes an inlet (20) for receiving the fluid; an outlet (28) for supplying the fluid for injection into the oil-carrying tube; an inlet valve (22) in a fluid path between the inlet and the outlet; an actuator (24) for opening and closing the valve; and a connector (36) for coupling the inlet to a fluid supply tube (32) extending between the device and a source of the fluid above the ground. A method of controlling injection of fluid using such a device is also provided.

Abstract: A fluid injection device (38) for deployment in a well-bore to control injection of fluid into an oil reservoir, wherein the well-bore has an outer pipe (16) and an inner tube (14) which extends within the outer pipe and is connected at one end to a pressurized fluid supply above the ground. The device includes a control valve arrangement comprising: an inlet (42) for receiving the fluid from the inner tube; an outlet (56) for outputting the fluid outside the inner tube; an inlet valve (44) in a fluid path between the inlet and the outlet; and an actuator (50) associated with the inlet valve which is controllable to switch the inlet valve between its open and closed configurations, such that when the inlet valve is open, the fluid flows from the inner tube, via the inlet, fluid path and outlet to outside the inner tube. A method of controlling injection of fluid into an oil reservoir from a well-bore using such a device is also provided.

Abstract: This invention relates to a method for producing corrugated material and processing strip material which is removed from the edges of the corrugated material during the formation process. The strip material is cut away from the corrugated material and expelled at a variable line speed to a trim processing machine. The line speed is measured by a sensor which provides a signal representation of the speed to a cutter assembly. The cutter assembly cuts the strip material at a cutting speed which is sequenced to the line speed such that the strip material is cut into a plurality of pieces. The pieces are generally uniform in shape and size across variations in the line speed as the cutting speed is synchronized with the line speed.

Abstract: Systems and methods are described that facilitate removing punch hole artifacts in electronic document images. When a document with punch holes is scanned, the punch holes appear as unwanted dark spots in the margin. To remove these artifacts, a blanking regions having background color pixels are placed over the punch hole artifacts and the electronic document image is stored with the blanking regions in place. A user interface is provided to permit a user to enter blanking region parameters, including x,y coordinates, diameter, reference edge from which the coordinates are measured, etc. Default settings can be stored and recalled for common punch hole patterns, which may vary between offices and the like.

Abstract: This invention relates to a method for producing corrugated material and processing strip material which is removed from the edges of the corrugated material during the formation process. The strip material is cut away from the corrugated material and expelled at a variable line speed to a trim processing machine. The line speed is measured by a sensor which provides a signal representation of the speed to a cutter assembly. The cutter assembly cuts the strip material at a cutting speed which is sequenced to the line speed such that the strip material is cut into a plurality of pieces. The pieces are generally uniform in shape and size across variations in the line speed as the cutting speed is synchronized with the line speed.

Abstract: Systems and methods are described that facilitate removing punch hole artifacts in electronic document images. When a document with punch holes is scanned, the punch holes appear as unwanted dark spots in the margin. To remove these artifacts, a blanking regions having background color pixels are placed over the punch hole artifacts and the electronic document image is stored with the blanking regions in place. A user interface is provided to permit a user to enter blanking region parameters, including x,y coordinates, diameter, reference edge from which the coordinates are measured, etc. Default settings can be stored and recalled for common punch hole patterns, which may vary between offices and the like.

Abstract: A snowmobile has a frame with a tunnel, a straddle seat, an engine-propelled drive track, and two skis. A steering device operatively connects to the at least one ski to steer the snowmobile. The steering device is positioned such that when the standard rider sits in a standard position on the seat, his knees are disposed in front of his ankles and below his hips. The rider's knees are also disposed sufficiently far below the steering device that the rider's knees do not interfere with steering the snowmobile. This rider positioning enables the rider to easily absorb bumps and to actively position himself on the snowmobile.

Abstract: An accumulator apparatus for paper collations having an accumulation chamber for receiving sheet material, the chamber defined by a fixed guide on one side, a movable guide on the other side and a movable stop member at one end. Rollers are included for driving the sheet material against the stop member, and gates are provided for moving the movable guide between a first position in which it is spaced from the fixed guide by a gap sufficiently small to prevent buckling of the sheet material as it is driven by the rollers against the stop member, and a second position in which the movable guide is spaced away from the fixed guide for discharge of the sheet material from the chamber.

Abstract: A method of transferring monies from a non-citizen resident of one country to their family members residing in another country, including setting up an account at a local bank in which funds will be deposited and from which funds will be transferred from, requesting an EFT from the bank to a non-banking institution in another country, providing for the recipient to present a cash equivalent device, adding the transferred monies to the recipient's cash equivalent device, and providing a call center where parties to the transaction may report issues and have issues resolved by personnel fluent in the native language of the parties.