Abstract: Systems and processes providing a tool for visualizing parallel dependency graph evaluation in computer animation are provided. Runtime evaluation data of a parallel dependency graph may be collected, including the start time and stop time for each node in the graph. The visualization tool may process the data to generate performance visualizations as well as other analysis features. Performance visualizations may illustrate the level of concurrency over time during parallel dependency graph evaluation. Performance visualizations may be generated by graphing node blocks according to node start time and stop time as well as the level of concurrency at a given time to illustrate parallelism. Performance visualizations may enable character technical directors, character riggers, programmers, and other users to evaluate how well parallelism is expressed in parallel dependency graphs in computer animation.

Abstract: Systems and processes providing a tool for visualizing parallel dependency graph evaluation in computer animation are provided. Runtime evaluation data of a parallel dependency graph may be collected, including the start time and stop time for each node in the graph. The visualization tool may process the data to generate performance visualizations as well as other analysis features. Performance visualizations may illustrate the level of concurrency over time during parallel dependency graph evaluation. Performance visualizations may be generated by graphing node blocks according to node start time and stop time as well as the level of concurrency at a given time to illustrate parallelism. Performance visualizations may enable character technical directors, character riggers, programmers, and other users to evaluate how well parallelism is expressed in parallel dependency graphs in computer animation.

Abstract: A container (100), comprising a thread (120) arranged around an opening (110) for engaging a corresponding thread (120) of a closure (400), more than four retention members (140) arranged around the opening (110), each retention member (140) having an end-face for abutting a member (510) on an interior surface of the closure (400) to impede unthreading of the closure (400), the retention members (140) being arranged such that a tangent (170) to each end-face of the retention members (140) intersects a plane (160, 350) bisecting the container (100) at an obtuse angle (171), wherein the retention members (140) are arranged in first and second groups, the first group (141, 410) comprising one retention member (140) having an end-face substantially parallel to the plane bisecting the container (100), and the second group (142, 420) comprising two or more retention members (140), the first and second groups being arranged on one side of the plane (160, 350), each in a respective quadrant of the container (100), th

Abstract: Systems and processes providing a tool for visualizing parallel dependency graph evaluation in computer animation are provided. Runtime evaluation data of a parallel dependency graph may be collected, including the start time and stop time for each node in the graph. The visualization tool may process the data to generate performance visualizations as well as other analysis features. Performance visualizations may illustrate the level of concurrency over time during parallel dependency graph evaluation. Performance visualizations may be generated by graphing node blocks according to node start time and stop time as well as the level of concurrency at a given time to illustrate parallelism. Performance visualizations may enable character technical directors, character riggers, programmers, and other users to evaluate how well parallelism is expressed in parallel dependency graphs in computer animation.

Abstract: Systems and processes providing a tool for visualizing parallel dependency graph evaluation in computer animation are provided. Runtime evaluation data of a parallel dependency graph may be collected, including the start time and stop time for each node in the graph. The visualization tool may process the data to generate performance visualizations as well as other analysis features. Performance visualizations may illustrate the level of concurrency over time during parallel dependency graph evaluation. Performance visualizations may be generated by graphing node blocks according to node start time and stop time as well as the level of concurrency at a given time to illustrate parallelism. Performance visualizations may enable character technical directors, character riggers, programmers, and other users to evaluate how well parallelism is expressed in parallel dependency graphs in computer animation.

Abstract: A container (100), comprising a thread (120) arranged around an opening (110) for engaging a corresponding thread (120) of a closure (400), more than four retention members (140) arranged around the opening (110), each retention member (140) having an end-face for abutting a member (510) on an interior surface of the closure (400) to impede unthreading of the closure (400), the retention members (140) being arranged such that a tangent (170) to each end-face of the retention members (140) intersects a plane (160, 350) bisecting the container (100) at an obtuse angle (171), wherein the retention members (140) are arranged in first and second groups, the first group (141, 410) comprising one retention member (140) having an end-face substantially parallel to the plane bisecting the container (100), and the second group (142, 420) comprising two or more retention members (140), the first and second groups being arranged on one side of the plane (160, 350), each in a respective quadrant of the container (100), th

Abstract: An oral drug delivery composition includes a sustained release component which includes a corticosteroid drug and which is contained within a capsule that has been treated so that the sustained release component is predominately released from the capsule in the intestine following oral administration. A drug delivery composition for delivering a corticosteroid drug to the intestine also includes: (a) a sustained release component comprising a corticosteroid drug, an alkali-containing ethylcellulose material and an acid; and (b) a delayed release component which substantially prevents release of the sustained release component until the composition reaches the intestine following oral administration. The compositions of the invention are useful for treating inflammatory diseases of the gastrointestinal tract, such as Crohn's disease and ulcerative colitis, and for treating glomerulonephritis.

Abstract: A system for deploying a plurality of independent payloads with a launch vehicle, the launch vehicle being longitudinally oriented about an axis, includes a plurality of launch modules. Each respective launch module of the plurality of launch modules includes a plurality of package elements. A respective predetermined set of package elements of the plurality of package elements comprises a respective payload of the plurality of payloads. Each respective launch module of the plurality of launch modules is situated in an abuttingly supporting relation with at least one adjacent launch module in a facing relation at an interface in a launch orientation. The interface is generally parallel with the axis. At least one restraining member cooperates with the plurality of launch modules to effect compressingly maintaining the plurality of launch modules in the launch orientation.

Abstract: A liquid aqueous formulation for the intranasal administration of apomorphine includes: (a) at least about 15 mg/ml of apomorphine; and (b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer); (ii) at least one cyclodextrin; and (iii) at least one cyclodextrin together with chitosan. The formulations of the invention can be used in the treatment or management of Parkinson's disease and erectile dysfunction.

Abstract: Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a basestock containing greater than or equal to 90% saturates and less than or equal to 0.03% sulphur or a mixture thereof, and respective minor amounts of an over-based metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and 5 to 500 mass %, based on the mass of detergent, of an oil-soluble alkyl-substituted substituted phenol other than a hindered phenol. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited.

Abstract: Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a Group II basestock, and respective minor amounts of an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and 5 to 500 mass %, based on the mass of the detergent, of an oil-soluble alkyl-substituted phenol other than a hindered phenol. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited.

Abstract: Embodiments of the present invention provide a container for liquid medicine disposal, wherein the container has one or more interior surfaces associated with activated carbon cloth for capturing a drug dissolved in the liquid medicine. Embodiments of the present invention are particularly intended for use when dispensing a medicine spray, wherein the container must be held inverted whilst dispensing the spray.

Abstract: Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a basestock containing greater than or equal to 90% saturates and less than or equal to 0.03% sulphur or a mixture thereof, and respective minor amounts of an over-based metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and at least 1 mass % of a hydrocarbyl-substituted carboxylic acid, anhydride, ester or amide thereof. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited.

Abstract: Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a Group II basestock, and respective minor amounts of an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and at least 1 mass % of a hydrocarbyl-substituted carboxylic acid, anhydride, ester or amide thereof. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited.

Abstract: In the field of pain relief and treatment there is a need for a device which is able to administer several predetermined doses of an opioid analgesic in a manner which can be done simply and safely by a patient or carer; in particular in a manner which minimises the risk of administering too great a dose at any one time. A device (10), for administering a predefined number (N) of predefined volume unit doses (Vu) of an opioid analgesic in liquid form, includes a closed container (12) which contains a predetermined fill volume (Vf) of the opioid analgesic, and a dispenser (14) that is connected to the container (12). The dispenser (14) is operable to administer an individual one volume unit dose (Vu) repeatedly said predefined number of times (N). Both the dispenser (14) is adapted, and the concentration of said opioid analgesic is chosen such that said volume unit dose is in the range 0.05 to 0.15 ml.

Abstract: An oral drug delivery composition includes a sustained release component which includes a corticosteroid drug and which is contained within a capsule that has been treated so that the sustained release component is predominately released from the capsule in the intestine following oral administration. A drug delivery composition for delivering a corticosteroid drug to the intestine also includes: (a) a sustained release component comprising a corticosteroid drug, an alkali-containing ethylcellulose material and an acid; and (b) a delayed release component which substantially prevents release of the sustained release component until the composition reaches the intestine following oral administration. The compositions of the invention are useful for treating inflammatory diseases of the gastrointestinal tract, such as Crohn's disease and ulcerative colitis, and for treating glomerulonephritis.

Abstract: A liquid aqueous formulation for the intranasal administration of apomorphine includes: (a) at least about 15 mg/ml of apomorphine; and (b) a solubilising agent selected from (i) at least one polyoxyethylene-polyoxypropylene copolymer (poloxamer); (ii) at least one cyclodextrin; and (iii) at least one cyclodextrin together with chitosan. The formulations of the invention can be used in the treatment or management of Parkinson's disease and erectile dysfunction.

Abstract: A system for deploying a plurality of independent payloads with a launch vehicle, the launch vehicle being longitudinally oriented about an axis, includes a plurality of launch modules. Each respective launch module of the plurality of launch modules includes a plurality of package elements. A respective predetermined set of package elements of the plurality of package elements comprises a respective payload of the plurality of payloads. Each respective launch module of the plurality of launch modules is situated in an abuttingly supporting relation with at least one adjacent launch module in a facing relation at an interface in a launch orientation. The interface is generally parallel with the axis. At least one restraining member cooperates with the plurality of launch modules to effect compressingly maintaining the plurality of launch modules in the launch orientation.

Abstract: A counterweight based rocket launch platform system and method uses gravity acting upon a counterweight to provide the initial assent for a rocket. This counterweight system is preferably built inside of a mountain so as to use the mountain as the supporting structure. By covering the exit opening with a thin membrane and closing the bottom, the system can have the air evacuated providing a free ascent without a terminal velocity. During the final moments of the ascent or after the rocket leaves the tube, the rocket will ignite carrying the payload into space. The velocity imparted to the rocket from the gravity assist in combination with bypassing the thickest part of the atmosphere will lower the amount of fuel required to lift payloads into space. This will result in increased payloads of existing rockets or the use of smaller and less expensive rockets.

Abstract: The mountain launch system is a method for using gravity acting upon a counterweight to provide the initial assent for a rocket and payload. This counterweight system is built inside of a mountain so as to use the mountain as the supporting structure. By covering the exit opening with a thin membrane and closing the bottom, the system can have the air evacuated providing a free-ascent without a terminal velocity. During the final moments of the ascent or after the rocket leaves the tube the rocket will ignite carrying the payload into space. The velocity imparted to the rocket from the gravity assist in combination with bypassing the thickest part of the atmosphere will lower the amount of fuel required to lift payloads into space. This will result in the use of smaller and less expensive rockets.