Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: A heat stake for a plastic part includes a body having a proximal end, a flared section and a distal end. The proximal end has a first cross-sectional area A1 and the flared section has a second cross-sectional area A2 where A1<A2. The distal end has a dual taper. That plastic part incorporating the heat stake is also disclosed.

Abstract: A device may store dependency information for a group of software components provided by a technical computing environment. The group of software components may include a first software component and a second software component and may identify the second software component as being a dependent software component of the first software component. The device may obtain an application generated via the technical computing environment and may determine that the application invokes the first software component. The device may access the dependency information based on the application invoking the first software component and may determine that the first software component invokes the second software component based on the dependency information. The device may generate a deployable form of the application that allows the application to run in another computing environment.

Abstract: A heat stake for a plastic part includes a body having a proximal end, a flared section and a distal end. The proximal end has a first cross-sectional area A1 and the flared section has a second cross-sectional area A2 where A1<A2. The distal end has a dual taper. That plastic part incorporating the heat stake is also disclosed.

Abstract: A device may store dependency information for a group of software components provided by a technical computing environment. The group of software components may include a first software component and a second software component and may identify the second software component as being a dependent software component of the first software component. The device may obtain an application generated via the technical computing environment and may determine that the application invokes the first software component. The device may access the dependency information based on the application invoking the first software component and may determine that the first software component invokes the second software component based on the dependency information. The device may generate a deployable form of the application that allows the application to run in another computing environment.

Abstract: A 1,3-diketoamide functional monomer represented by the following formula (1): wherein R and Y are independently selected from the group consisting of hydrogen, an alkyl group having from 1 to 10 carbon atoms, an aryl group having from 6 to 20 carbon atoms, and an aralkyl group having from 7 to 20 carbon atoms; and wherein X and Z are independently selected from the group consisting of an alkyl group having from 1 to 10 carbon atoms, an aryl group having from 6 to 20 carbon atoms, and an aralkyl group having from 7 to 20 carbon atoms. Also disclosed are emulsion, suspension, and solution polymers comprising residues from the 1,3-diketoamide functional monomer of formula 1 and, optionally, one or more additional ethylenically unsaturated monomers. Both latex and self-curing coating compositions described herein exhibit excellent hydrolytic stability, including increased retention of 1,3-diketo functionality.

Abstract: A 1,3-diketoamide functional monomer represented by the following formula (1): wherein R and Y are independently selected from the group consisting of hydrogen, an alkyl group having from 1 to 10 carbon atoms, an aryl group having from 6 to 20 carbon atoms, and an aralkyl group having from 7 to 20 carbon atoms; and wherein X and Z are independently selected from the group consisting of an alkyl group having from 1 to 10 carbon atoms, an aryl group having from 6 to 20 carbon atoms, and an aralkyl group having from 7 to 20 carbon atoms. Also disclosed are emulsion, suspension, and solution polymers comprising residues from the 1,3-diketoamide functional monomer of formula 1 and, optionally, one or more additional ethylenically unsaturated monomers. Both latex and self-curing coating compositions described herein exhibit excellent hydrolytic stability, including increased retention of 1,3-diketo functionality.

Abstract: An apparatus for providing multiple collimated light beams from optical fibers and the method for producing such beams. The apparatus includes first and second optical fibers that carry light of first and second wavelengths, respectively, a fixture that maintains the fibers in a fixed relationship to one another, and a collimating lens. Light from each of the first and second optical fibers diverges from a face of the fixture. The collimating lens produces first and second collimated light beams that are displaced relative to one another from the light leaving the face. The face of the fixture is positioned to correct for chromatic aberration in the lens.

Abstract: An apparatus for providing multiple collimated light beams from optical fibers and the method for producing such beams. The apparatus includes first and second optical fibers that carry light of first and second wavelengths, respectively, a fixture that maintains the fibers in a fixed relationship to one another, and a collimating lens. Light from each of the first and second optical fibers diverges from a face of the fixture. The collimating lens produces first and second collimated light beams that are displaced relative to one another from the light leaving the face. The face of the fixture is positioned to correct for chromatic aberration in the lens.

Abstract: A wave energy converter has a primary body interconnected to a secondary body such that the bodies may oscillate longitudinally relative to one another. A slug mass is visco-elastically connected to the primary body. The slug mass has effective mass, stiffness and damping characteristics. A generator is drivingly connected between the primary and secondary bodies. The generator has a load damping characteristic. At least one of the characteristics is dynamically controllable, allowing the bodies' longitudinal motion to be varied in response to wave motion changes of the wave environment in which the wave energy converter is deployed, to maintain out-of-phase oscillation of the bodies, thus increasing the driving force imparted to the generator and thereby increasing the generator's electrical energy output.

Abstract: Aqueous dispersions of water-insoluble polyolefin-based adhesion promoters are formed by dissolving the adhesion promoter in at least one olefinically unsaturated monomer, forming a mini-emulsion with high shear in the presence of water, surfactant and other additives, and then polymerizing the monomer with a monomer-soluble, substantially water insoluble radical initiator. The polymerized product, a stable dispersion (latex) of polyolefin adhesion promoter and polymerized monomer in water, is useful as a primer or as an additive for improving the adhesion of coatings to polyolefin substrates.

Abstract: A wave energy converter (100, 200 or 300) has a primary body (102, 202 or 302) interconnected to a secondary body (104, 204 or 304) such that the bodies may oscillate longitudinally relative to one another. A slug mass (106, 208 or 308) is visco-elastically connected to the primary body. The slug mass has effective mass, stiffness and damping characteristics. A generator (108, 216 or 316) is drivingly connected between the primary and secondary bodies. The generator has a load damping characteristic. At least one of the aforementioned characteristics is dynamically controllable, allowing the bodies' longitudinal motion to be varied in response to wave motion changes of the wave environment in which the wave energy converter is deployed, to maintain out-of-phase oscillation of the bodies, thus increasing the driving force imparted to the generator and thereby increasing the generator's electrical energy output.

Abstract: A louvre controller for a linear light source has plural transverse reflectors 33 and each located between side reflectors 31, 32. The transverse reflectors have arcuate surfaces forming a double concave reflector and a base 38 of the transverse reflectors is profiled to provide predetermined vertical cut-off angles for all horizontal angles of azimuth.

Abstract: The present invention is directed toward automatically integrating a late bound program language into an external environment. The external environment may be an early bound environment, a late bound environment or some combination thereof. Associated with the late bound program environment is a modular execution engine and an interface mechanism, wherein the interface mechanism is capable of expressing late bound semantics in a format compatible with the external environment.

Abstract: Systems and methods for using the same to select probes specific for a target nucleic acid are provided. Also provided are computer program products for executing the subject methods.

Abstract: Methods are disclosed for predicting the performance of oligonucleotide probes by identifying the sequence of a candidate probe, generating experimental data for the probe and using the data to train a statistical regression model. Nucleic acid arrays containing probes with performance predicted by the described using methods are provided. Also included are algorithms for performing the subject methods recorded on computer-readable media, and computational systems for analysis.

Abstract: Comparative genomic hybridization is a tool that compares DNA samples from suspect cells of an organism with DNA samples from normal cells. Cross-species comparative genomic hybridization visualization allows genomic data from model organisms to be mapped and presented in accordance with the (for example) human genome to suggest possible common biological effects between two or more species.