Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: Described herein are heterocycle substituted pyridine derivative antifungal agents and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of fungal diseases and infections.

Abstract: A device may store dependency information for a group of software components provided by a technical computing environment. The group of software components may include a first software component and a second software component and may identify the second software component as being a dependent software component of the first software component. The device may obtain an application generated via the technical computing environment and may determine that the application invokes the first software component. The device may access the dependency information based on the application invoking the first software component and may determine that the first software component invokes the second software component based on the dependency information. The device may generate a deployable form of the application that allows the application to run in another computing environment.

Abstract: A device may store dependency information for a group of software components provided by a technical computing environment. The group of software components may include a first software component and a second software component and may identify the second software component as being a dependent software component of the first software component. The device may obtain an application generated via the technical computing environment and may determine that the application invokes the first software component. The device may access the dependency information based on the application invoking the first software component and may determine that the first software component invokes the second software component based on the dependency information. The device may generate a deployable form of the application that allows the application to run in another computing environment.

Abstract: An apparatus for providing multiple collimated light beams from optical fibers and the method for producing such beams. The apparatus includes first and second optical fibers that carry light of first and second wavelengths, respectively, a fixture that maintains the fibers in a fixed relationship to one another, and a collimating lens. Light from each of the first and second optical fibers diverges from a face of the fixture. The collimating lens produces first and second collimated light beams that are displaced relative to one another from the light leaving the face. The face of the fixture is positioned to correct for chromatic aberration in the lens.

Abstract: An apparatus for providing multiple collimated light beams from optical fibers and the method for producing such beams. The apparatus includes first and second optical fibers that carry light of first and second wavelengths, respectively, a fixture that maintains the fibers in a fixed relationship to one another, and a collimating lens. Light from each of the first and second optical fibers diverges from a face of the fixture. The collimating lens produces first and second collimated light beams that are displaced relative to one another from the light leaving the face. The face of the fixture is positioned to correct for chromatic aberration in the lens.

Abstract: The present invention is directed toward automatically integrating a late bound program language into an external environment. The external environment may be an early bound environment, a late bound environment or some combination thereof. Associated with the late bound program environment is a modular execution engine and an interface mechanism, wherein the interface mechanism is capable of expressing late bound semantics in a format compatible with the external environment.

Abstract: Systems and methods for using the same to select probes specific for a target nucleic acid are provided. Also provided are computer program products for executing the subject methods.

Abstract: Methods are disclosed for predicting the performance of oligonucleotide probes by identifying the sequence of a candidate probe, generating experimental data for the probe and using the data to train a statistical regression model. Nucleic acid arrays containing probes with performance predicted by the described using methods are provided. Also included are algorithms for performing the subject methods recorded on computer-readable media, and computational systems for analysis.

Abstract: Comparative genomic hybridization is a tool that compares DNA samples from suspect cells of an organism with DNA samples from normal cells. Cross-species comparative genomic hybridization visualization allows genomic data from model organisms to be mapped and presented in accordance with the (for example) human genome to suggest possible common biological effects between two or more species.

Abstract: Probe selection methods, computer program products, systems and arrays are provided. The probes can be used, for example, in genome scanning applications such as array CGH and/or location analysis.

Abstract: There are a number of sensors (2, 22) such as thermocouples which can provide a putative measurand signal which is within a predicted range for such signals whilst the sensor is incorrectly operating, such as as due to an open circuit. Techniques and processes are available to determine by interrogation sensor operational validity, but these can distort the measurand signal if correct. By time division multiplex techniques the present arrangement takes a putative measurand signal from a sensor (2, 22) in order that either within the same time division or more normally a separate time division, an interrogation of the sensor is performed in order to determine accuracy and therefore validity of the sensor 22.

Abstract: A method of ensuring the integrity of read-only components in deployed mixed-mode applications that includes generating a digital fingerprint prior to the deployment of a mixed-mode application is discussed. The digital fingerprint is based on a read-only component in the mixed-mode application and uniquely identifies the read-only component. The method also deploys the mixed-mode application and the digital fingerprint. Additionally, the method verifies, at execution time by using the digital fingerprint, that the read-only component in the mixed-mode deployed application that served as the basis for the digital fingerprint is identical to the same read-only component originally packaged with the mixed-mode application.

Abstract: The present invention is directed toward automatically integrating a late bound program language into an external environment. The external environment may be an early bound environment, a late bound environment or some combination thereof. Associated with the late bound program environment is a modular execution engine and an interface mechanism, wherein the interface mechanism is capable of expressing late bound semantics in a format compatible with the external environment.