Abstract: The present teaching relates to methods, systems, and programming for reconciling or merging real time data with bulk data. In one example, a first attribute value is obtained. The first attribute value characterizes an aspect of a data item. A second attribute value related to the first attribute value is obtained. The second attribute value characterizes the aspect of the data item. A scheme is selected to be used to determine a third attribute value to characterize the data item. The third attribute value is determined in accordance with the selected scheme as well as the first and second attribute values.

Abstract: The present teaching relates to methods, systems, and programming for reconciling or merging real time data with bulk data. In one example, a first attribute value is obtained. The first attribute value characterizes an aspect of a data item. A second attribute value related to the first attribute value is obtained. The second attribute value characterizes the aspect of the data item. A scheme is selected to be used to determine a third attribute value to characterize the data item. The third attribute value is determined in accordance with the selected scheme as well as the first and second attribute values.

Abstract: The present invention provides nucleic acid molecules comprising one or more nucleic acid sequences encoding a polypeptide having a detectable activity. The present invention also provides methods of joining such nucleic acid molecules to nucleic acid molecules to be assayed for promoter activity. The present invention also relates to methods of preparing fusion proteins comprising a polypeptide of interest and a polypeptide having a detectable activity.

Abstract: The present invention provides nucleic acid molecules comprising one or more nucleic acid sequences encoding a polypeptide having a detectable activity. The present invention also provides methods of joining such nucleic acid molecules to nucleic acid molecules to be assayed for promoter activity. The present invention also relates to methods of preparing fusion proteins comprising a polypeptide of interest and a polypeptide having a detectable activity.

Abstract: In one embodiment, a knowledge base is automatically built for enriching feeds coming from different sources and that have tags of different conventions, by deducting which tags go into various categories of knowledge. In one embodiment, method for a relationship between objects is determined based on the relationships between their tags.

Abstract: The present invention provides nucleic acid molecules comprising one or more nucleic acid sequences encoding a polypeptide having a detectable activity. The present invention also provides methods of joining such nucleic acid molecules to nucleic acid molecules to be assayed for promoter activity. The present invention also relates to methods of preparing fusion proteins comprising a polypeptide of interest and a polypeptide having a detectable activity.

Abstract: In one embodiment, a knowledge base is automatically built for enriching feeds coming from different sources and that have tags of different conventions, by deducting which tags go into various categories of knowledge. In one embodiment, method for a relationship between objects is determined based on the relationships between their tags.

Abstract: In one embodiment, a knowledge base is automatically built for enriching feeds coming from different sources and that have tags of different conventions, by deducting which tags go into various categories of knowledge.

Abstract: The present invention provides nucleic acid molecules comprising one or more nucleic acid sequences encoding a polypeptide having a detectable activity. The present invention also provides methods of joining such nucleic acid molecules to nucleic acid molecules to be assayed for promoter activity. The present invention also relates to methods of preparing fusion proteins comprising a polypeptide of interest and a polypeptide having a detectable activity.

Abstract: A method of identifying a compound that modulates the activity of a cellular regulator is provided. The method consists of contacting a sample containing a cellular regulator and a nucleic acid element acted on by the cellular regulator with a test compound under conditions that allow replication or expression of the nucleic acid element or a gene or MRNA operatively linked to the nucleic acid element or gene, and an increase or decrease in the amount of replication or expression in the presence of the test compound compared to the absence of the test compound indicates that the compound has cellular regulator modulatory activity. A method of treating a HCV infection is also provided.

Abstract: The present invention provides a high complexity substantially complete hairpin ribozyme library having a randomized recognition sequence, packaged in a vector and operably linked to a promoter suitable for high level expression in a wide variety of cells. The invention comprises using the library in a variety of selection protocols for identifying, isolating and characterizing known or unknown target RNAs, to reveal the phenotypic effects of such cleavage, and to identify the gene products that produce those phenotypic effects.

Abstract: The present invention provides a hairpin ribozyme library having a randomized recognition sequence, packaged in a vector and operably linked to a promoter suitable for high level expression in a wide variety of cells. The invention comprises using the library in a variety of selection protocols for identifying, isolating and characterizing known or unknown target RNAs, to reveal the phenotypic effects of such cleavage, and to identify the gene products that produce those phenotypic effects.

Abstract: The present invention provides a hairpin ribozyme library having a randomized recognition sequence, packaged in a vector and operably linked to a promoter suitable for high level expression in a wide variety of cells. The invention comprises using the library in a variety of selection protocols for identifying, isolating and characterizing known or unknown target RNAs, to reveal the phenotypic effects of such cleavage, and to identify the gene products that produce those phenotypic effects.

Abstract: The present invention provides a high complexity substantially complete hairpin ribozyme library having a randomized recognition sequence, packaged in a vector and operably linked to a promoter suitable for high level expression in a wide variety of cells. The invention comprises using the library in a variety of selection protocols for identifying, isolating and characterizing known or unknown target RNAs, to reveal the phenotypic effects of such cleavage, and to identify the gene products that produce those phenotypic effects.