Patents by Inventor Peter Werner Feit
Peter Werner Feit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4082851Abstract: The invention relates to a series of new compounds, salts thereof and to methods for the preparation of the compounds which have the general formula ##STR1## in which R.sub.1 stands for an unsubstituted or substituted phenoxy, phenylthio, benzyl, phenylsulfinyl, or anilino radical;R.sub.2 stands for a -YR.sub.2 ' radical, in which Y represents -O-, -S-, or -NH-, and R.sub.2 ' represents C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl or -alkynyl; or methyl or ethyl substituted with phenyl, furyl, thienyl or pyridyl;R.sub.3 and R.sub.4 which can be the same or different, and unsubstituted or substituted, stand for hydrogen or for a straight or branched C.sub.1 -C.sub.8 -alkyl, C.sub.2 -C.sub.8 -alkenyl or -alkynyl radical, a C.sub.5 -C.sub.7 -cycloalkyl, a phenyl, or a 5-, 6- or 7-membered heterocyclic ring system containing not more than two hetero atoms selected from the group consisting of oxygen, sulphur and nitrogen, or for a C.sub.1 -C.sub.Type: GrantFiled: June 16, 1976Date of Patent: April 4, 1978Assignee: Leo Pharmaceutical Products Ltd.Inventors: Peter Werner Feit, Ole Bent Tvaermose Nielsen, Herta Bruun, Claus Aage Svensgaard Bretting
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Patent number: 4018794Abstract: Compounds of the general formulae ##STR1## in which R.sub.1 represents a straight or branched, optionally substituted alkyl, alkenyl or alkynyl radical; R.sub.2 stands for an optionally substituted phenyl radical; Y stands for oxygen, sulphur or a methylene radical; X stands for O or H.sub.2 ; their salts and esters and methods for their preparation.The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.Type: GrantFiled: February 19, 1975Date of Patent: April 19, 1977Assignees: Leo Pharmaceutical Products Ltd., A/S Lovens Kemiske Fabrik ProduktionsaktieselskabInventors: Peter Werner Feit, Ole Bent Tvaermose Nielsen
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Patent number: 3989745Abstract: The present invention relates to a series of new compounds, their salts and esters and to methods for the preparation of the compounds having the general formula: ##SPC1##In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for hydrogen or a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl, alkynyl or alkoxy radical, optionally being substituted with halogen, a lower alkoxy or di-(lower alkyl) amino radical; Ar stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, or lower alkoxy; Y stands for oxygen, sulphur or a methylene radical.Type: GrantFiled: June 7, 1974Date of Patent: November 2, 1976Assignee: Lovens Kemiske Fabrik ProduktionsaktieselskabInventors: Peter Werner Feit, Ole Bent Tvaermose Nielsen, Herta Bruun
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Patent number: 3985777Abstract: This invention relates to new, therapeutically active compounds of the general formula ##SPC1##In which A represents one of the groupings ##EQU1## R.sup.2 --S--, R.sup.2 --OS--, and R.sup.2 --O.sub.2 S--, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 each represents hydrogen, an aliphatic radical, a cycloaliphatic radical, or an aromatically, cycloaliphatically, or heterocyclically substituted aliphatic radical, in addition to which R.sup.2 and R.sup.3 may each represent an aromatic or heterocyclic radical, and when A is ##EQU2## R.sup.1 and R.sup.2 may be linked to form a 5- to 8-membered heterocyclic ring system, which may have one or more nitrogen atoms, sulphur atoms, or oxygen atoms in addition to the nitrogen atom linked to R.sup.1 and R.sup.2 ; R.sup.5 is hydrogen or lower alkyl; and R.sup.6 is hydrogen or lower alkyl or acyl; to salts, esters, and amides of the said compounds; and to methods for the production of the compounds.Type: GrantFiled: November 15, 1973Date of Patent: October 12, 1976Assignee: Lovens Kemiske Fabrik ProduktionsaktieselskabInventor: Peter Werner Feit
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Patent number: 3972886Abstract: Compounds of the general formula ##SPC1##In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; X and Y stand for oxygen or sulphur; their salts and esters and methods for their preparation. The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.Type: GrantFiled: March 17, 1975Date of Patent: August 3, 1976Assignees: Leo Pharmaceutical Products Ltd., A/S Lovens Kemiske Fabrik ProduktionsakieselskabInventors: Peter Werner Feit, Ole Bent Tvaermose Nielsen, Herta Bruun
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Patent number: 3971819Abstract: This invention relates to new, therapeutically active compounds of the general formula ##SPC1##In which A represents one of the groupings ##EQU1## R.sup.2 --O--, R.sup.2 --S--, R.sup.2 --OS--, and R.sup.2 --O.sub.2 S--, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 each represents hydrogen, an aliphatic radical, a cycloaliphatic radical, or an aromatically, cycloaliphatically, or heterocyclically substituted aliphatic radical, in addition to which R.sup.2 and R.sup.3 may each represent an aromatic or heterocyclic radical, and when A is ##EQU2## R.sup.1 and R.sup.2 may be linked to form a 5- to 8-membered heterocyclic ring system, which may have one or more nitrogen atoms, sulphur atoms, or oxygen atoms in addition to the nitrogen atom linked to R.sup.1 and R.sup.2 ; R.sup.5 is hydrogen or lower alkyl; and R.sup.6 is hydrogen or lower alkyl or acyl; to salts, esters, and amides of the said compounds; and to methods for the production of the compounds.Type: GrantFiled: November 15, 1973Date of Patent: July 27, 1976Assignee: Lovens Kemiske Fabrik ProduktionsaktieselskabInventor: Peter Werner Feit
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Patent number: 3950376Abstract: Compounds of the general formula ##SPC1##In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; X and Y stand for oxygen or sulphur; their salts and esters and methods for their preparation.The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.Type: GrantFiled: June 18, 1973Date of Patent: April 13, 1976Assignee: Leo Pharmaceutical Products Ltd. A/SInventors: Peter Werner Feit, Ole Bent Tvaermose Nielsen, Herta Bruun
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Patent number: 3950380Abstract: The present invention relates to a series of new compounds, their salts and esters and to methods for the preparation of the compounds having the general formula: ##SPC1##In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; Ar stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; Y stands for O, S, NH or a CH.sub.2 radical; and YR.sub.1 is placed in the 2- or 3-position.The compounds of the invention which are valuable in the human and veterinary practice, possess a pronounced diuretic and/or saluretic activity.Type: GrantFiled: August 20, 1974Date of Patent: April 13, 1976Assignee: Leo Pharmaceutical Products Ltd. A/SInventors: Peter Werner Feit, Ole Bent Tvaermose Nielsen, Herta Bruun