Abstract: A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patient's body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.

Abstract: A method of making a compound magnet that comprises a plurality of regions at least some of which have different magnetization directions. The method comprises assembling a plurality of sections of magnetizable material having a preferred direction of magnetization into a block, each section corresponding to a region or a part of a region, and the preferred magnetization direction of each section being aligned with the desired magnetization direction of its corresponding region. The sections in the assembled block are magnetized to form the compound magnet.

Abstract: An apparatus and method for interventional navigation within a subject's body is provided in which a medical device having at least one electrostrictive element is adapted to cause the distal end of the medical device to bend in a given direction for improving navigation. The medical device may further comprise at least one magnetically responsive element on the distal end, which may be oriented in the approximate direction of a magnetic field that is applied to the subjects body. At least one method for navigating a medical device though a subject's body is provided, by changing the direction of an applied magnetic field to align a magnetically responsive element on the distal end for orienting the distal end, and by applying a voltage to at least one electrostrictive element disposed in the distal portion of the device for causing the distal end to change orientation from that achieved by application of the magnetic field alone.

Abstract: An elongate medical device is provided that may be magnetically navigated through a subject's body, which includes an extendable and retractable tip element disposed on the distal end of the medical device. The tip element is configured to be retracted prior to advancing the distal end of the medical device towards a target area within the subject's body, and to be controllably extended towards the target area within the subject's body. An actuation means is provided for controllably extending the tip element, which enables fine control of the advancement of the tip of the medical device towards a target location within a subject's body. The actuation means may be achieved through hydraulic pressure application to an expandable volume, electrical current application to a material that responsively changes length, electrical current application to an electromagnet for responsively repelling and displacing a magnet, and mechanical force application for displacing a spring-loaded mechanism.

Abstract: A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patient's body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.

Abstract: An apparatus and method for locating a magnetic implant in a surgical application using the field of a source magnet for the implant guiding field. The source magnet is an electromagnet having a separate calibrated magnetic field component in addition to the guiding field, so that both the magnitude and orientation of the magnetic field as a function of position around the magnet are known. A magnetic implant is provided with a sensor, such as a three-axis Hall effect sensor, to provide an indication of the magnitude and orientation of an applied magnetic field when the implant is surgically implanted in a patient. After implantation, the source magnet is energized with a current having a modulated component.

Abstract: An electrophysiology catheter includes a tube having a proximal end, a distal end, and a lumen therebetween. The tube is preferably comprised of multiple sections of different flexibility, arranged so that the flexibility of the catheter increases from the proximal end to the distal end. There is a first generally hollow electrode member at the distal end. At least one magnetically responsive element is disposed at least partially in the hollow electrode, for orienting the distal end of the catheter with an externally applied magnetic field. Multiple magnets can be distributed over the distal portion of the device. The end electrode can have openings for delivering irrigating fluid, and/or a sleeve can be provided around the tube to create an annular space for the delivering of irrigating fluid. A temperature sensor can be provided to control the operation of the catheter. A localization coil can also be included to sense the position and orientation of the catheter.

Abstract: An automated system for navigating a medical device through the lumens and cavities in an operating region in a patient. The system includes an elongate medical device, having a proximal end and a distal end adapted to be introduced into the operating region. The system also includes an imaging system for displaying an image of the operating region, including a representation of the distal end of the medical device in the operating region. The system also includes a localization system for determining the position of the medical device in a frame of reference translatable to the displayed image of the imaging system. Finally, the system includes a system for orienting the medical device in a selected direction in the operating region, this system may be, for example, a magnetic navigation system which acts through the interaction of magnetic fields associated with the medical device inside the operating region and at least one external source magnet outside the patient's body.

Abstract: Embolic devices and materials include an expansible polymer, and magnetically responsive material that allow the embolic devices and materials to be guided into, and held within, vascular defects, while the expansible polymer expands. In some embodiments, the expansion of the expansible polymer reduces the density of the magnetic material, so that subsequent magnetic surgery and magnetic imaging procedures can still employed.

Abstract: A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patients body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.

Abstract: A magnetically navigable atherectomy device includes a cutting head, a flexible drive shaft having a proximal and a distal end, with the cutting device on the distal end, and a magnet associated with the cutting head, the magnet of sufficient size to allow the cutting head to be oriented by an externally applied magnetic field. The magnet may be a portion of the cutting head made from a magnetically permeable or permanent magnetic material, a portion of the drive shaft made from a magnetically permeable or permanent magnetic material; a separate magnet between the cutting head and the drive shaft, a portion a magnet on a sheath covering the drive shaft. Alternatively a guide wire can provided with a magnetic material on its distal end. Through the application of a magnetic field and/or a magnetic gradient, the artherectomy device can be guided to the location of the atheromatous material in the body.

Abstract: Generally, the shielded x-ray source of the present invention has a cast shield of an iron based material substantially enclosing and closely conforming to the x-ray tube to shield the x-ray tube imaging beam from interference from magnetic fields. The method of the present invention includes providing a shield cast from an iron-based material in a shape having a cavity to receive and closely conform to the x-ray tube, and installing the cast shield around the x-ray tube. The magnetic surgical system comprising at least one magnetic for magnetically navigating a medical device in an operating region in a patient's body, and an imaging apparatus including at least one x-ray tube for imaging the operating region. A cast shield of an iron-based material substantially enclosing and closely conforming to the at least one x-ray tube.