Patents by Inventor Peter WESSELS
Peter WESSELS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6790860Abstract: The present invention relates to pyrrolidine derivatives useful as inhibitors of metalloproteases, e.g. zinc proteases, and which are effective in treating disease states associated with vasoconstriction.Type: GrantFiled: February 25, 2003Date of Patent: September 14, 2004Assignee: Hoffmann-La Roche Inc.Inventors: Johannes Aebi, Daniel Bur, Alexander Chucholowski, Henrietta Dehmlow, Eric Argirios Kitas, Ulrike Obst, Hans Peter Wessel
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Publication number: 20040034231Abstract: The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: 1Type: ApplicationFiled: August 12, 2003Publication date: February 19, 2004Inventors: Jean Ackermann, Leo Alig, Alexander Chucholowski, Katrin Groebke, Kurt Hilpert, Holger Kuehne, Ulrike Obst, Lutz Weber, Hans Peter Wessel
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Patent number: 6683215Abstract: The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: wherein R1, E, X1 to X4 and G1 and G2 are as defined in the description and the claims, as well as hydrates or solvates and physiologically usable salts thereof.Type: GrantFiled: October 4, 2002Date of Patent: January 27, 2004Assignee: Hoffman-La Roche Inc.Inventors: Jean Ackermann, Leo Alig, Alexander Chucholowski, Katrin Groebke, Kurt Hilpert, Holger Kuehne, Ulrike Obst, Lutz Weber, Hans Peter Wessel
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Patent number: 6660902Abstract: Absorbent article such as a diaper, pant diaper, incontinence guard, sanitary napkin, wound dressing or the like comprising a layer of continuous fibers (9), so called tow, which is bonded in points, spots or lines in a bonding pattern (10), but where the fibers otherwise are substantially unbonded to each other. The layer can either be used as a liquid acquisition layer (5) in the article under the topsheet (2), as a topsheet (12) or as a combined topsheet and liquid acquisition layer (22).Type: GrantFiled: June 9, 1999Date of Patent: December 9, 2003Assignee: SCA Hygine Products ABInventors: Urban Widlund, Christina Steger, Roy Hansson, Sofia Roxendal, Peter Wessel
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Publication number: 20030199569Abstract: The present invention relates to pyrrolidine derivatives useful as inhibitors of metalloproteases, e.g. zinc proteases, and which are effective in treating disease states associated with vasoconstriction.Type: ApplicationFiled: February 25, 2003Publication date: October 23, 2003Inventors: Johannes Aebi, Daniel Bur, Alexander Chucholowski, Henrietta Dehmlow, Eric Argirios Kitas, Ulrike Obst, Hans Peter Wessel
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Publication number: 20030083504Abstract: The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: 1Type: ApplicationFiled: October 4, 2002Publication date: May 1, 2003Inventors: Jean Ackermann, Leo Alig, Alexander Chucholowski, Katrin Groebke, Kurt Hilpert, Holger Kuehne, Ulrike Obst, Lutz Weber, Hans Peter Wessel
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Patent number: 6548694Abstract: N-(4-carbamimidoyl-phenyl)-glycine derivatives have the formula: wherein X and R1 to R5 are as defined herein, and includes hydrates or solvates and/or physiologically acceptable salts thereof and/or physiologically acceptable esters thereof.Type: GrantFiled: May 16, 2001Date of Patent: April 15, 2003Assignee: Hoffman-La Roche Inc.Inventors: Leo Alig, Katrin Groebke Zbinden, Kurt Hilpert, Holger Kuehne, Ulrike Obst, Hans Peter Wessel
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Patent number: 6511566Abstract: Method of producing a fibrous material layer mainly intended to be incorporated in an absorbent article such as a diaper, pant diaper, incontinence guard, sanitary napkin or the like. At least one bundle of continuous filaments, so called tow (12), is opened and the filaments are separated and evened to a layer having the desired fiber distribution, after which the layer is bonded in points, spots or lines in a bonding pattern, but where the filaments otherwise are substantially unbonded to each other.Type: GrantFiled: December 3, 1998Date of Patent: January 28, 2003Assignee: SCA Hygiene Products ABInventors: Peter Wessel, Urban Nilsson, Kent Edgren, José-Maria Mansisidor, Dragoljub Kustrimovic
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Publication number: 20020185439Abstract: A process is provided for the removal of organic substances (TOC), pesticides or other specific compounds from an aqueous salt solution, for example from a regenerate derived from water purification. The TOC-containing aqueous salt solution is treated in a desalination membrane according to the dead-end principle, wherein neither longitudinal flow over the membrane with air and/or water, nor continuous concentrate discharge takes place, after which the obtained permeate is reused, and the concentrate obtained after flushing is discharged. The TOC-containing aqueous salt solution is introduced at the feed side of the membrane module at a flux of 5-75 1/m2·h, a feed pressure of 4-12 bars for 30-40 minutes, while the obtained TOC-depleted permeate is discharged. Preferably, operation takes place at a flux of 15-25 1/m2·hr, a pressure of approximately 8 bars, and the duration of treatment is approximately 30 minutes.Type: ApplicationFiled: March 1, 2002Publication date: December 12, 2002Applicant: DHV Water B.V.Inventors: Leo Peter Wessels, Wilhelmus Cornelis Van Paassen, Harry Futselaar, Walterus Gijsbertus Joseph Van Der Meer
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Patent number: 6476264Abstract: The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: wherein R1, E, X1 to X4 and G1 and G2 are as defined in the description and the claims, as well as hydrates or solvates and physiologically usable salts thereof.Type: GrantFiled: January 12, 2001Date of Patent: November 5, 2002Assignee: Hoffmann-La Roche Inc.Inventors: Jean Ackermann, Leo Alig, Alexander Chucholowski, Katrin Groebke, Kurt Hilpert, Holger Kuehne, Ulrike Obst, Lutz Weber, Hans Peter Wessel
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Publication number: 20020040146Abstract: The present invention relates to pyrrolidine derivatives useful as inhibitors of metalloproteases, e.g. zinc proteases, and which are effective in treating disease states associated with vasoconstriction.Type: ApplicationFiled: July 17, 2001Publication date: April 4, 2002Inventors: Johannes Aebi, Daniel Bur, Alexander Chucholowski, Henrietta Dehmlow, Eric Argirios Kitas, Ulrike Obst, Hans Peter Wessel
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Patent number: 6242644Abstract: The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula: wherein R1, E, X1 to X4 and G1 and G2 are as defined in the description and the claims, as well as hydrates or solvates and physiologically usable salts thereof.Type: GrantFiled: December 14, 1999Date of Patent: June 5, 2001Assignee: Hoffmann-La Roche Inc.Inventors: Jean Ackermann, Leo Alig, Alexander Chucholowski, Katrin Groebke, Kurt Hilpert, Holger Kuehne, Ulrike Obst, Lutz Weber, Hans Peter Wessel
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Patent number: 6242601Abstract: The compounds of formula (I) wherein R1, R2 and X have the significance as given in the description, are inhibitors of endothelin receptors and can therefore be used for the treatment of disorders which are associated with abnormal vascular tone and endothelial dysfunction.Type: GrantFiled: January 13, 2000Date of Patent: June 5, 2001Assignee: Hoffman-La Roche Inc.Inventors: Volker Breu, Philippe Coassolo, Rolf Huber, Werner Neidhart, Henri Ramuz, Sébastien Roux, Hans Peter Wessel
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Patent number: 5830920Abstract: Compounds of the formula ##STR1## wherein n.sup.1 -n.sup.9 are each independently 0 or 1;m.sup.1 -m.sup.9 are each independently 0 or 1, but with the proviso that at least one of m.sup.1, m.sup.2 and m.sup.3, at least one of m.sup.4, m.sup.5 and m.sup.6 and, when present, at least one of m.sup.7, m.sup.8 and m.sup.9 is 1; and whereinX.sup.1 -X.sup.18 each independently is --O--, --CONR.sup.1,--NR.sup.1 CO-- or --NR.sup.1 --;R.sup.1 is hydrogen or lower alkyl;W is a benzene or s-triazine;Y.sup.1 -Y.sup.9 each independently is an aromatic ring systems;A.sup.1 -A.sup.3 each independently is a residue of a sugar alcohol devoid of the 1-hydroxy group or a derivative thereof, a residue of a sugar acid devoid of the 1-carboxy group or a derivative thereof or tris-(hydroxymethyl)-methyl;D is the di-residue of a sugar alcohol devoid of 2 hydroxy groups or a derivative thereof or the di-residue of a sugar dicarboxylic acid devoid of 2 carboxy group or a derivative thereof;Q.sup.1 -Q.sup.3 and Z.sup.Type: GrantFiled: April 26, 1996Date of Patent: November 3, 1998Assignee: Hoffmann-La Roche Inc.Inventors: Alexander Chucholowski, Jurgen Fingerle, Niggi Iberg, Hans Peter Marki, Rita Muller, Michael Pech, Marianne Rouge, Gerard Schmid, Thomas Tschopp, Hans Peter Wessel
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Patent number: 5767268Abstract: Compounds of formulas ##STR1## wherein, B is lower alkylene or an optionally substituted aromatic ring system;G.sup.1, G.sup.2 and G.sup.3 each independently signify a residue of a glycopyranoside, a glycopyranose or a derivative thereof, with at least one hydroxy group of residue G.sup.1, G.sup.2 or G.sup.3 being esterified with sulfuric acid, and pharmaceutically usable salts thereof, are useful for the treatment of disorders which are characterized by excessive or destructive proliferation of smooth muscle cells.Type: GrantFiled: April 26, 1996Date of Patent: June 16, 1998Assignee: Hoffmann-La Roche Inc.Inventors: Alexander Chucholowski, Jurgen Fingerle, Niggi Iberg, Hans Peter Marki, Rita Muller, Michael Pech, Marianne Rouge, Gerard Schmid, Thomas Tschopp, Hans Peter Wessel
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Patent number: 5763436Abstract: Compounds of the formula ##STR1## wherein L, M, R, T and X are set forth in the description, as well as hydrates or solvates thereof, which inhibit thrombin-induced platelet aggregation and clotting of fibrinogen in plasma, are described. The compounds of formula I are prepared by amidination or, depending on whether L is NH or O, by amide formation or esterification.Type: GrantFiled: September 17, 1996Date of Patent: June 9, 1998Assignee: Hoffmann-La Roche Inc.Inventors: Jean Ackermann, David Banner, Klaus Gubernator, Paul Hadvary, Kurt Hilpert, Klaus Muller, Ludvik Labler, Gerard Schmid, Thomas B. Tschopp, Hans Peter Wessel, Beat Wirz
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Patent number: 4630055Abstract: A dipole arrangement which is located in a sheath,including segments of ejectable dipoles sequentially arranged within the sheath. The dipole can be ejected from the sheath within a short time interval and, subsequent to ejection, will rapidly form a large-surfaced and homogeneous cloud. The segments of the sheath which has a polished inner surface, as viewed in the ejecting direction, evidence an envelopment with a reducing number of windings which consists of a thin metal foil, smooth on both sides thereof, and wherein the dipoles of the enveloped segments, or the only partially enveloped segments, are centripetally pretensioned. The dipoles which are prestressed in the segments act as drive springs for the metal foil which encompass the segment whereby, dependent upon the winding number of the metal foil, there is achieved a time-delayed release of the dipoles.Type: GrantFiled: June 14, 1983Date of Patent: December 16, 1986Assignee: Diehl GmbH & Co.Inventor: Peter Wessel
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Patent number: 4003760Abstract: A method for applying a coating on metal articles that is resistant to chemical and mechanical attack including the steps of first applying a galvanic zinc coating over a metal article, next applying a chromate coating over the zinc coating, drying the chromate coating, and thereafter applying a fluoroplastic resinous coating over the chromate coating.Type: GrantFiled: March 1, 1974Date of Patent: January 18, 1977Assignee: Mecano-Bundy GmbHInventors: Wolfgang Labenski, Heinz Paul Schapitz, Hans-Peter Wessel