Patents by Inventor Peter Wiktor
Peter Wiktor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220128547Abstract: Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.Type: ApplicationFiled: June 2, 2021Publication date: April 28, 2022Inventors: Peter Wiktor, Joshua Labaer, Peter Kahn, Bharath Takulapalli, Ji Qiu, Al Brunner, Mitch Magee
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Publication number: 20210039091Abstract: A microreactor array platform and method for sealing a reagent in microreactors of an array of microreactors are provided. The microreactor array platform includes an array of microreactors, and a sealing film having a first surface and an opposite second surface, the sealing film configured to movably seal the array of microreactors. The microreactor array platform also includes an injector for delivering a reagent into the array of microreactors via a fluid path between the array and the second surface of the sealing film, and an applicator for directing a sealing liquid against the first surface of the sealing film. The microreactor array platform further includes a system for creating a pressure differential between the reagent in the injector and a space between the array of microreactors and the second surface of the sealing film.Type: ApplicationFiled: October 13, 2020Publication date: February 11, 2021Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventor: Peter Wiktor
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Patent number: 10850278Abstract: A microreactor array platform and method for sealing a reagent in microreactors of an array of microreactors are provided. The microreactor array platform includes an array of microreactors, and a sealing film having a first surface and an opposite second surface, the sealing film configured to movably seal the array of microreactors. The microreactor array platform also includes an injector for delivering a reagent into the array of microreactors via a fluid path between the array and the second surface of the sealing film, and an applicator for directing a sealing liquid against the first surface of the sealing film. The microreactor array platform further includes a system for creating a pressure differential between the reagent in the injector and a space between the array of microreactors and the second surface of the sealing film.Type: GrantFiled: January 28, 2015Date of Patent: December 1, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventor: Peter Wiktor
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Patent number: 10241011Abstract: The invention provides methods and devices for preparing frozen vitrified samples for transmission electron microscopy. By reducing the volume of sample from microliter scale to picoliter scale, the requirement for blotting of excess fluid is minimized or eliminated.Type: GrantFiled: July 11, 2017Date of Patent: March 26, 2019Assignees: The Scripps Research Institute, Engineering Arts LLCInventors: Bridget Carragher, Clinton S. Potter, Tilak Jain, Peter Kahn, Peter Wiktor
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Publication number: 20180267029Abstract: Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.Type: ApplicationFiled: March 28, 2018Publication date: September 20, 2018Inventors: Peter Wiktor, Joshua Labaer, Peter Kahn, Bharath Takulapalli, Ji Qiu, Al Brunner, Mitch Magee
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Publication number: 20170350798Abstract: The invention provides methods and devices for preparing frozen vitrified samples for transmission electron microscopy. By reducing the volume of sample from microliter scale to picoliter scale, the requirement for blotting of excess fluid is minimized or eliminated.Type: ApplicationFiled: July 11, 2017Publication date: December 7, 2017Inventors: Bridget Carragher, Clinton S. Potter, Tilak Jain, Peter Kahn, Peter Wiktor
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Patent number: 9702795Abstract: The invention provides methods and devices for preparing frozen vitrified samples for transmission electron microscopy. By reducing the volume of sample from microliter scale to picoliter scale, the requirement for blotting of excess fluid is minimized or eliminated.Type: GrantFiled: January 14, 2013Date of Patent: July 11, 2017Assignee: The Scripps Research InstituteInventors: Bridget Carragher, Clinton S. Potter, Tilak Jain, Peter Kahn, Peter Wiktor
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Publication number: 20160339427Abstract: A microreactor array platform and method for sealing a reagent in microreactors of an array of microreactors are provided. The microreactor array platform includes an array of microreactors, and a sealing film having a first surface and an opposite second surface, the sealing film configured to movably seal the array of microreactors. The microreactor array platform also includes an injector for delivering a reagent into the array of microreactors via a fluid path between the array and the second surface of the sealing film, and an applicator for directing a sealing liquid against the first surface of the sealing film. The microreactor array platform further includes a system for creating a pressure differential between the reagent in the injector and a space between the array of microreactors and the second surface of the sealing film.Type: ApplicationFiled: January 28, 2015Publication date: November 24, 2016Inventor: Peter Wiktor
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Publication number: 20160258944Abstract: A microreactor array system includes an array of microreactors, and a sealing membrane having a first surface and an opposite second surface, the sealing membrane configured to movably seal the array of microreactors. The microreactor array system further includes a reagent gap providing a fluid path between the array of microreactors and the second surface of the sealing membrane when the second surface of the sealing membrane is in spaced relationship with the array of microreactors. The microreactor array system further includes an injector for delivering a reagent into the reagent gap, an applicator for directing a working fluid against the first surface of the sealing membrane, and a detector.Type: ApplicationFiled: February 26, 2016Publication date: September 8, 2016Inventor: Peter Wiktor
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Publication number: 20140371091Abstract: Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.Type: ApplicationFiled: October 24, 2012Publication date: December 18, 2014Inventors: Peter Wiktor, Joshua Labaer, Peter Kahn, Bharath Takulapalli, Ji Qiu, Al Brunner, Mitch Magee
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Publication number: 20140360286Abstract: The invention provides methods and devices for preparing frozen vitrified samples for transmission electron microscopy. By reducing the volume of sample from microliter scale to picoliter scale, the requirement for blotting of excess fluid is minimized or eliminated.Type: ApplicationFiled: January 14, 2013Publication date: December 11, 2014Inventors: Bridget Carragher, Clinton S. Potter, Tilak Jain, Peter Kahn, Peter Wiktor
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Publication number: 20120231533Abstract: A chamber device for analyzing living cell(s). The chamber device includes a base and a lid that when reversibly pressed closed create a chamber. The base is configured with an optically transparent well to contain at least one cell. The lid has a breadth greater than the base and is configured to contain at least one sensor. The lid is further configured with a lip that when pressed between the lid and the base creates an impermeable seal. The base and the lid are configured so that, when closed and in use, the sensor remains spatially apart from the at least one cell.Type: ApplicationFiled: October 28, 2009Publication date: September 13, 2012Inventors: Mark R. Holl, Deirdre R. Meldrum, A. Cody Youngbull, Haixin Zhu, Jeff Houkal, Yanqing Tian, Shashanka Ashili, Laimonas Kelbauskas, Roger Johnson, Shih-hui Chao, Peter Wiktor, Alex Jen, Lloyd Burgess, Sarah McQuaid, Ai Brunner, Peter Kahn
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Publication number: 20020150511Abstract: A piezoelectric pipetting device housing and methods for making and using the same is disclosed. A protected capillary includes a rigid tube and a glass capillary that is bonded to an interior surface of the rigid tube. The protected capillary optionally includes a piezoelectric actuating element adjacent a portion of the exterior surface of the glass capillary. The protected capillary further optionally includes a sensor that is adjacent a third portion of the exterior surface of the glass capillary or a temperature regulator. Methods for making and using the protected capillary are also disclosed.Type: ApplicationFiled: March 1, 2002Publication date: October 17, 2002Inventor: Peter Wiktor
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Patent number: 6232129Abstract: A piezoelectric actuated device for acquiring and dispensing fluid samples is described. Fluid samples are acquired or drawn up into the device by dipping the tip into a fluid and applying an alternating current electrical signal to the piezoelectric element. Removing the tip from the fluid and applying another electrical signal causes drops of fluid to be ejected for non-contact dispensing. The device optionally incorporates a second piezoelectric element functioning as a sensor to detect if it is empty, plugged or working properly. An optional heater, temperature sensor and feedback circuitry regulate the temperature of the device.Type: GrantFiled: February 3, 1999Date of Patent: May 15, 2001Inventor: Peter Wiktor
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Patent number: 5785926Abstract: A high precision, small volume fluid processing system employs open ended capillary tubes to meter, aliquot and mix small volumes of sample fluid and reagents. The system has an automatic mechanism for moving the capillary tubes as well as automated sub-systems for incubating and mixing fluids within the capillary tubes.Type: GrantFiled: September 19, 1995Date of Patent: July 28, 1998Assignees: University of Washington, GeneTools, Inc.Inventors: Ronald Seubert, Maynard V. Olson, Deirdre Meldrum, Blake Hannaford, Peter Wiktor, Neal A. Friedman, Donald B. Snow, Ray Kraft