Patents by Inventor Peter Willibrord Thies

Peter Willibrord Thies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4256642
    Abstract: Pharmaceutically active 2,9-dioxatricyclo[4,3,1,0.sup.3,7 ] decanes and the process for their production and the production of various intermediates are disclosed. Pharmaceutical compositions containing an effective amount of the novel compounds and a pharmaceutically acceptable carrier are also disclosed.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: March 17, 1981
    Assignee: Kali-Chemie Pharma GmbH
    Inventors: Peter Willibrord Thies, Akiji Asai
  • Patent number: 4117148
    Abstract: 3-AZIDOMETHYL-2,9-DIOXATRICYCLO[4,3,1,0.sup.3,7 ] DECANE DERIVATIVES ARE DISCLOSED WHICH EXHIBIT ANALGESIC, AS WELL AS ANTIPYRETIC AND ANTIPHLOGISTIC PROPERTIES, AND WHICH HAVE THE FORMULA (I) ##STR1## wherein: R.sub.1 represents alkyloxy or aralkyloxy;One of R.sub.2 and R.sub.3 is hydrogen and the other represents hydroxy, acyloxy or carbamyloxy, or R.sub.2 and R.sub.3 jointly represent oxygen; and,Y and y' each represent hydrogen or jointly form a bond,As well as pharmaceutical formulations thereof.By reducing the 3-azidomethyl compounds of formula (I), the corresponding 3-aminomethyl compounds are obtained which possess sedative properties and which are valuable intermediates for preparing 3-(mono- or dialkylaminomethyl)-2,9-dioxatricyclo[4,3,1,0.sup.3,7 ] decanes which exhibit sedative and soporific activities.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: September 26, 1978
    Assignee: Kali-Chemie Pharma GmbH.
    Inventors: Peter Willibrord Thies, Samuel David
  • Patent number: 4089971
    Abstract: Pharmaceutically active 2,9-dioxatricyclo[4,3,1,0.sup.3,7 ] decanes and the process for their production and the production of various intermediates are disclosed. Pharmaceutical compositions containing an effective amount of the novel compounds and a pharmaceutically acceptable carrier are also disclosed.
    Type: Grant
    Filed: October 15, 1976
    Date of Patent: May 16, 1978
    Assignee: Kali-Chemie Pharma GmbH
    Inventors: Peter Willibrord Thies, Akiji Asai
  • Patent number: 4016176
    Abstract: Compounds consisting of esters of 4-hydroxy-2,9-dioxatricyclo[4.3.1.0.sup.3,7 ] decane having the formulae: ##STR1## in which formulae R.sub.1 is an alkyl radical having at most 4 carbon atoms, one of the radicals R.sub.2 and R.sub.3 is hydrogen and, when R.sub.2 is a hydrogen radical, R.sub.3 is a carbamyloxy radical and, when R.sub.3 is a hydrogen radical, R.sub.2 is a carbamyloxy, or an alkanoyl radical having at most 5 carbon atoms, the said carbamyloxy radical having the formula --OCONHR in which R is a hydrogen allyl, phenyl, cyclohexyl or an alkyl radical having at most 4 carbon atoms. The compounds are useful as sedatives and narcotics and can be produced by several different processes.
    Type: Grant
    Filed: October 30, 1975
    Date of Patent: April 5, 1977
    Assignee: Kali-Chemie Pharma GmbH
    Inventor: Peter Willibrord Thies