Abstract: Two-component vaccine formulations and methods are contemplated where the vaccine has an adjuvant component and a therapeutic component. The therapeutic component comprises preferably a recombinant therapeutic virus encoding a therapeutic antigen while the adjuvant component comprises a non-host cell or immune stimulating portion thereof. Notably, use of the adjuvant component will result in significant uptake of the therapeutic component into immune competent cells, even in the absence of receptors for entry of the therapeutic component. In addition, such adjuvant also stimulates expression of the therapeutic antigen.

Abstract: The present invention relates to crystalline forms of the free base of the c-Met inhibitor, Compound 1. The invention also relates to crystalline forms of salts of Compound 1. The invention also relates to pharmaceutical compositions comprising the solid polymorphs of the free base and salts of Compound 1. The invention further relates to methods of treating a disease, disorder, or syndrome mediated at least in part by modulating in vivo activity of a protein kinase.

Abstract: A scope system includes a processor and a scope device. The scope device includes a handle configured to remain outside of the body and an elongated shaft extending from the handle to a distal tip and including a working channel extending therethrough. The working channel is open at the distal tip of the shaft. The shaft is inserted through a bodily lumen to a target surgical site. The shaft includes at least one sensor transmitting to the processor sensor data relating to the target surgical site.

Abstract: An information processing system includes an information processing device, a food material stock managing device disposed in a food material storage device, and a meal condition detecting device. The information processing device includes a display device including a display screen, a first communicating circuit that communicates with a portable terminal of a target person, a second communicating circuit that communicates with the food material stock managing device, a third communicating circuit that communicates with the meal condition detecting device, a processor, and a memory storing instructions that cause the information processing device to generate information regarding proposed food to be provided to the target person based on information obtained from the first, second, and third communicating circuits, and display the information regarding the proposed food to be provided to the target person on the display screen of the display device.

Abstract: Systems and methods for managing a storage device are disclosed. A first amount of a first storage device is associated to a first client. A first request associated with first data is detected, and a second request associated with the first data is also detected. A log for the first request and the second request is maintained for the first client. A trigger condition is identified, and based on identifying the trigger condition, a value is computed based on the log. A second amount of the first storage device is determined based on the value, and the second amount is associated to the first client.

Abstract: A reagent reaction determination method and device applied to a test tube, a computer-readable storage medium and a test tube, wherein, the reagent reaction determination method comprises: outputting a brightness control signal to the light-incident component to control the light-incident component to emit the RGB light, and to adjust the brightness control signal according to a preset step length, so as to adjust the brightness of the RGB light; detecting brightness variations of the light derived by the light-emergent component to generate an electrical signal detection value; perform an interpolation calculation on the present brightness control signal to obtain an estimated value of the brightness control signal when the electrical signal detection value is less than a preset threshold, and determining a reaction result in the reagent reaction chamber according to the estimated value of the brightness control signal. The reagent reaction determination device can greatly improve the user experience.

Abstract: A method for preparing a bacteria repellant masterbatch, bacteria repellant polymer composites comprising the same, and compositions and articles prepared therefrom.

Abstract: An operation room system includes a processing unit configured to receive data associated with a patient; determine a treatment for the patient; identify a control setting associated with one or more treatment devices that are (i) in communication with the processing unit, and (ii) operable to perform the treatment; and generate a display including the control setting and at least one view of the data.

Abstract: A population of capsules, the capsules can include a core including a benefit agent and a shell surrounding the core, wherein the shell can include a first shell component.

Abstract: A beam clamp for attachment to a flange of a structural building member and from which to support or brace a service component. The beam clamp has a clamp body, and a set screw. The clamp body includes a first jaw section with at least one mounting through hole, a second jaw section, a joining section that interconnects the first and second jaw sections, and a transverse opening that is to receive the flange. A contact surface on the second jaw section is formed with surface irregularities providing a roughness that enhances engagement of the contact surface with the flange. In use of the beam clamp, the contact surface is in contact with the flange of the structural member, the set screw is installed in the mounting through hole, and the flange is secured within transverse opening between the tip of the set screw and the contact surface.

Abstract: A method of facilitating a virtual meeting using virtual interactions with three-dimensional virtual objects to change statuses of issues being tracked by an issue tracking system may include, causing a three-dimensional virtual environment to be displayed to a first user and a second user, the three-dimensional virtual environment including a representation of the first user, a representation of the second user, a representation of a three-dimensional workspace, a first virtual object displayed in the three-dimensional workspace and representing a first issue in an issue tracking system, and a second virtual object displayed in the three-dimensional workspace and representing a second issue in the issue tracking system.

Abstract: The present invention relates to crystalline forms of the free base of the c-Met inhibitor, Compound 1. The invention also relates to crystalline forms of salts of Compound 1. The invention also relates to pharmaceutical compositions comprising the solid polymorphs of the free base and salts of Compound 1. The invention further relates to methods of treating a disease, disorder, or syndrome mediated at least in part by modulating in vivo activity of a protein kinase.

Abstract: A method includes selecting a first machine learning model from a plurality of machine learning models that are trained for use in performing geolocation, wherein the first machine learning model is selected to perform geolocation within a first cell of a plurality of cells of a wireless network, acquiring event data from a plurality of wireless devices within the first cell, grouping the event data into a plurality of records, wherein each record of the plurality of records contains event data that indicates a common wireless device of the plurality of wireless devices, a common cell of the plurality of cells, and a common timestamp, and generating a predicted location of a first wireless device of the plurality of wireless devices, using the first machine learning model, wherein the first machine learning model outputs the predicted location in response to an input of a record of the plurality of records.

Abstract: Bacteria repellant polymer composite having a reduced yellowness index prepared by melt processing a base polymer an epoxy resin and a bacteria repellant agent and methods of preparation thereof.

Abstract: The present invention relates to crystalline forms of salts of Compound 1. The invention also relates to pharmaceutical compositions comprising the solid crystalline salts of Compound 1. The invention further relates to methods of treating a disease, disorder, or syndrome mediated at least in part by modulating in vivo activity of a protein kinase.

Abstract: The present invention relates to crystalline forms of the free base of the c-Met inhibitor, Compound 1. The invention also relates to crystalline forms of salts of Compound 1. The invention also relates to pharmaceutical compositions comprising the solid polymorphs of the free base and salts of Compound 1. The invention further relates to methods of treating a disease, disorder, or syndrome mediated at least in part by modulating in vivo activity of a protein kinase.

Abstract: Aspects of the subject disclosure may include, for example, obtaining an indication that a communication device can access a communication service via a first radio access technology, configuring, responsive to the obtaining of the indication, the communication service in accordance with the first radio access technology, resulting in a configured communication service, receiving a request for the communication service from the communication device, and providing the configured communication service to the communication device responsive to the receiving of the request. Other embodiments are disclosed.

Abstract: A method includes selecting a first machine learning model from a plurality of machine learning models that are trained for use in performing geolocation, wherein the first machine learning model is selected to perform geolocation within a first cell of a plurality of cells of a wireless network, acquiring event data from a plurality of wireless devices within the first cell, grouping the event data into a plurality of records, wherein each record of the plurality of records contains event data that indicates a common wireless device of the plurality of wireless devices, a common cell of the plurality of cells, and a common timestamp, and generating a predicted location of a first wireless device of the plurality of wireless devices, using the first machine learning model, wherein the first machine learning model outputs the predicted location in response to an input of a record of the plurality of records.

Abstract: This disclosure describes an anti-viral, anti-bacterial and anti-fungal portable personal toilet seat that is resistant to algae, mold and mildew and that can be safely folded and held without the danger of pinched fingers and without a handle.