Patents by Inventor Peter Woodruff

Peter Woodruff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADJUNCTIVE TREATMENT OF MYCOBACTERIAL DISEASES
    Publication number: 20250205260
    Abstract: Disclosed herein are azidodeoxy- and aminodeoxy trehalose (TreAz and TreNH2) compounds that inhibit Mycobacterium tuberculosis (an etiological agent of TB) biofilm (an in vitro model of intent TB infection) formation via blocking of the adaptive strategy used by M. tuberculosis form biofilm, termed trehalose catalytic shift. Prior to our work, such compounds were never tested for inhibition of mycobacterial biofilm formation. Our work defined this class of compounds' mechanism of action and showed for the first time that they sensitize drug-tolerant mycobacteria to existing clinically used antibiotics. The disclosed compounds are potential drugs for adjunctive treatment of TB and related mycobacterial diseases.
    Type: Application
    Filed: March 21, 2023
    Publication date: June 26, 2025
    Applicants: UNIVERSITY OF SOUTHERN CALIFORNIA, CENTRAL MICHIGAN UNIVERSITY, UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES
    Inventors: Hyungjin EOH, Benjamin SWARTS, Peter WOODRUFF, Jae Jin LEE
  • Chemoenzymatic synthesis of trehalose analogues
    Patent number: 11879147
    Abstract: The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: January 23, 2024
    Inventors: Benjamin M. Swarts, Peter Woodruff
  • CHEMOENZYMATIC SYNTHESIS OF TREHALOSE ANALOGUES
    Publication number: 20210108247
    Abstract: The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 15, 2021
    Inventors: Benjamin M. Swarts, Peter Woodruff
  • Chemoenzymatic synthesis of trehalose analogs
    Patent number: 10876143
    Abstract: The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: December 29, 2020
    Assignees: Central Michigan University, University of Maine System
    Inventors: Benjamin M. Swarts, Peter Woodruff
  • Chemoenzymatic Synthesis of Trehalose Analogs
    Publication number: 20180119196
    Abstract: The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues.
    Type: Application
    Filed: December 18, 2017
    Publication date: May 3, 2018
    Inventors: Benjamin M. Swarts, Peter Woodruff
  • Chemoenzymatic synthesis of trehalose analogs
    Patent number: 9873905
    Abstract: The present invention provides methods of synthesizing trehalose analogs; methods of detecting mycobacteria, and trehalose analogs.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: January 23, 2018
    Assignees: Central Michigan University, University of Maine System
    Inventors: Benjamin M. Swarts, Peter Woodruff
  • Chemoenzymatic Synthesis of Trehalose Analogs
    Publication number: 20150252402
    Abstract: The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues.
    Type: Application
    Filed: March 6, 2015
    Publication date: September 10, 2015
    Inventors: Benjamin M. Swarts, Peter Woodruff
  • Sleeping bag and system
    Patent number: 7438078
    Abstract: There is a combination sleeping bag system. There is a tent member, including a tent base, a tent wall coupled to the tent base and defining a tent interior, and a tent aperture through the tent wall; and a sleeping bag defining a sleeping cavity, extending through the tent aperture, and including a head portion disposed within the tent interior, a foot portion disposed exterior the tent member, and a storage cavity accessible from the sleeping cavity.
    Type: Grant
    Filed: August 5, 2005
    Date of Patent: October 21, 2008
    Inventors: Peter Woodruff, Ronald Shawn Naccarato, Tony Reece
  • Sleeping bag and system
    Publication number: 20070028952
    Abstract: There is a combination sleeping bag system. There is a tent member, including a tent base, a tent wall coupled to the tent base and defining a tent interior, and a tent aperture through the tent wall; and a sleeping bag defining a sleeping cavity, extending through the tent aperture, and including a head portion disposed within the tent interior, a foot portion disposed exterior the tent member, and a storage cavity accessible from the sleeping cavity.
    Type: Application
    Filed: August 5, 2005
    Publication date: February 8, 2007
    Inventors: Peter Woodruff, Ronald Naccarato, Tony Reece