Patents by Inventor Petr Gibala

Petr Gibala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS WITH LOW AMOUNTS OF NITROSAMINE IMPURITIES AND METHODS FOR PRODUCING THE SAME
    Publication number: 20230390221
    Abstract: The present invention relates to pharmaceutical compositions comprising metformin with low amounts of nitrosamine impurities and methods for producing the same. More specifically, the present invention relates to methods and compositions that reduce the amount of nitrosable compounds in the active pharmaceutical ingredient and/or reduce the conversion of nitrosable compounds into nitrosamines in the finished dosage form.
    Type: Application
    Filed: October 15, 2021
    Publication date: December 7, 2023
    Applicant: Zentiva K.S.
    Inventors: Jaroslav RIHA, Ludek RIDVAN, Michal DOUSA, Tomas KUBELKA, Petr GIBALA, Frantisek BARTACEK, Pawel STASIAK, Stanislav KALASEK, Anna Kluk, Vít Zvonícek
  • SPECIFIC IMPURITIES OF MONTELUKAST
    Publication number: 20110034692
    Abstract: The subject-matter of the invention consists in a method of removing specific impurities of montelukast of formula (I), which occur due to chemical instability of the target substance and also contaminate the substance in the preparation process. Further, methods of isolation of specific impurities of montelukast defined by formulae (V-A), (IV-A), (XIIIa-A), (XIIIb-A) and analytic methods used for the control of the production of montelukast in the pharmaceutical quality.
    Type: Application
    Filed: March 11, 2009
    Publication date: February 10, 2011
    Applicant: ZENTIVA, K.S.
    Inventors: Ales Halama, Olga Bouskova, Petr Gibala, Josef Jirman