Patents by Inventor Petr Ilyinskii

Petr Ilyinskii has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIGH AFFINITY IL-2 RECEPTOR AGONISTS AND IMMUNOSUPPRESSANTS TO ENHANCE IMMUNE TOLERANCE
    Publication number: 20230381277
    Abstract: Disclosed are methods and related compositions for administering a high affinity IL-2 receptor agonist in combination with immunosuppressants. The methods and compositions provided can be used for enhancing regulatory T cells, including antigen-specific regulatory T cells.
    Type: Application
    Filed: April 7, 2023
    Publication date: November 30, 2023
    Inventors: Takashi Kei Kishimoto, Petr Ilyinskii
  • IMMUNOSUPPRESSANTS IN COMBINATION WITH ANTI-IGM AGENTS AND RELATED DOSING
    Publication number: 20230357437
    Abstract: Provided herein are methods and related compositions or kits for administering viral transfer vectors in combination with an immunosuppressant and an anti-IgM agent.
    Type: Application
    Filed: March 8, 2023
    Publication date: November 9, 2023
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS AND RELATED DOSING
    Publication number: 20230322884
    Abstract: Disclosed are methods and related compositions for administering a high affinity IL-2 receptor agonist in combination with immunosuppressants. The methods and compositions provided can be used for modulating an immune response to an antigen, such as by enhancing regulatory T cells, such as antigen-specific regulatory T cells.
    Type: Application
    Filed: March 8, 2023
    Publication date: October 12, 2023
    Inventors: Takashi Kei Kishimoto, Petr Ilyinskii
  • METHODS AND COMPOSITIONS FOR INDUCING AUTOPHAGY
    Publication number: 20230147052
    Abstract: Provided herein are methods and compositions related to compositions comprising synthetic nanocarriers comprising an immunosuppressant. Also provided herein are methods and compositions for inducing or increasing autophagy.
    Type: Application
    Filed: April 14, 2020
    Publication date: May 11, 2023
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR ATTENUATING ANTI-VIRAL TRANSFER VECTOR IGM RESPONSES
    Publication number: 20230141563
    Abstract: Provided herein are methods and related compositions or kits for administering viral transfer vectors in combination with synthetic nanocarriers comprising an immunosuppressant and an anti-IgM agent.
    Type: Application
    Filed: October 12, 2022
    Publication date: May 11, 2023
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS TO ENHANCE IMMUNE TOLERANCE
    Publication number: 20220323607
    Abstract: Disclosed are methods and related compositions for administering a high affinity IL-2 receptor agonist in combination with immunosuppressants. The methods and compositions provided can be used for enhancing regulatory T cells, including antigen-specific regulatory T cells.
    Type: Application
    Filed: April 8, 2022
    Publication date: October 13, 2022
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Petr Ilyinskii
  • METHODS AND COMPOSITIONS USING SYNTHETIC NANOCARRIERS COMPRISING IMMUNOSUPPRESSANT
    Publication number: 20210290601
    Abstract: Provided herein are methods and compositions related to synthetic nanocarriers comprising an immunosuppressant that can be used, for example, for inducing autophagy and/or promoting a tolerogenic phenotype.
    Type: Application
    Filed: February 26, 2021
    Publication date: September 23, 2021
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASES AND DISORDERS
    Publication number: 20210154324
    Abstract: Provided herein are methods and compositions related to compositions comprising synthetic nanocarriers comprising an immunosuppressant. Also provided herein are methods and compositions for the preventative and therapeutic treatment of liver toxicity, diseases and disorders, such as inflammation-induced, infection-induced or drug-induced hepatotoxicity.
    Type: Application
    Filed: October 21, 2020
    Publication date: May 27, 2021
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses
    Patent number: 10933129
    Abstract: Disclosed are methods for generating humoral and cytotoxic T lymphocyte (CTL) immune responses in a subject and related compositions.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: March 2, 2021
    Assignee: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Conlin O'Neil, Petr Ilyinskii
  • METHODS AND COMPOSITIONS FOR ATTENUATED ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSE
    Publication number: 20200390718
    Abstract: Provided herein are methods and related compositions or kits for administering viral transfer vectors in combination with synthetic nanocarriers comprising an immunosuppressant and a corticosteroid.
    Type: Application
    Filed: May 28, 2020
    Publication date: December 17, 2020
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Petr Ilyinskii
  • METHODS FOR TREATMENT OF SUBJECTS WITH PREEXISTING IMMUNITY TO VIRAL TRANSFER VECTORS
    Publication number: 20200360453
    Abstract: Provided herein are methods and related compositions for administering viral vectors with synthetic nanocarriers comprising an immunosuppressant to subjects. Such subjects may be subjects with pre-existing immunity against a viral antigen of the viral vector.
    Type: Application
    Filed: April 28, 2020
    Publication date: November 19, 2020
    Applicant: Selecta Biosciences, Inc.
    Inventors: Takashi Kei Kishimoto, Petr Ilyinskii
  • METHODS AND COMPOSITIONS FOR ATTENUATING ANTI-VIRAL TRANSFER VECTOR IGM RESPONSES
    Publication number: 20190142974
    Abstract: Provided herein are methods and related compositions or kits for administering viral transfer vectors in combination with synthetic nanocarriers comprising an immunosuppressant and an anti-IgM agent.
    Type: Application
    Filed: October 12, 2018
    Publication date: May 16, 2019
    Inventors: Petr Ilyinskii, Christopher J. Royma, Takashi Kei Kishimoto
  • PATTERNED DOSING OF IMMUNOSUPPRESSANTS COUPLED TO SYNTHETIC NANOCARRIERS
    Publication number: 20180193482
    Abstract: Provided herein are methods and related compositions for administering viral vectors and synthetic nanocarriers comprising an immunosuppressant. In some embodiments, the methods and compositions provided herein achieve improved transgene expression and/or immune response reduction, such as downregulated IgM and/or IgG immune responses.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 12, 2018
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Takashi Kei Kishimoto
  • POLYESTER POLYMER MATRICES FOR THE DELIVERY OF ALLERGENS
    Publication number: 20180071394
    Abstract: Provided herein are polyester polymer synthetic nanocarriers that encapsulate allergens as well as methods of their use and production.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 15, 2018
    Inventors: Conlin O'Neil, Petr Ilyinskii
  • DOSE SELECTION OF ADJUVANTED SYNTHETIC NANOCARRIERS
    Publication number: 20180043023
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Application
    Filed: August 23, 2017
    Publication date: February 15, 2018
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • Dose selection of adjuvanted synthetic nanocarriers
    Patent number: 9764031
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: September 19, 2017
    Assignee: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • DOSE SELECTION OF ADJUVANTED SYNTHETIC NANOCARRIERS
    Publication number: 20150328309
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Application
    Filed: May 20, 2015
    Publication date: November 19, 2015
    Applicant: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • Dose selection of adjuvanted synthetic nanocarriers
    Patent number: 9066978
    Abstract: Disclosed are synthetic nanocarrier compositions with coupled adjuvant compositions as well as related methods.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: June 30, 2015
    Assignee: Selecta Biosciences, Inc.
    Inventors: Petr Ilyinskii, Grayson B. Lipford, Charles Zepp
  • CONTROL OF ANTIBODY RESPONSES TO SYNTHETIC NANOCARRIERS
    Publication number: 20130039954
    Abstract: Disclosed are synthetic nanocarrier compositions that comprise B cell antigen for desired antibody production and an off-target response attenuating polymeric coating as well as related methods.
    Type: Application
    Filed: July 27, 2012
    Publication date: February 14, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: Lynnelle Ann McNamee Pittet, David H. Altreuter, Yun Gao, Petr Ilyinskii, William Kuhlman
  • SYNTHETIC NANOCARRIERS THAT GENERATE HUMORAL AND CYTOTOXIC T LYMPHOCYTE (CTL) IMMUNE RESPONSES
    Publication number: 20130028941
    Abstract: Disclosed are methods for generating humoral and cytotoxic T lymphocyte (CTL) immune responses in a subject and related compositions.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Conlin O'Neil, Petr Ilyinskii