Patents by Inventor Petr Kocis

Petr Kocis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230414541
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof, based upon a combination of APOE4 status and disease severity.
    Type: Application
    Filed: September 6, 2023
    Publication date: December 28, 2023
    Inventors: Susan ABUSHAKRA, Aidan POWER, Martin TOLAR, John HEY, Jeremy YU, Petr KOCIS
  • Publication number: 20230133465
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: February 16, 2022
    Publication date: May 4, 2023
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20230087041
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Application
    Filed: July 29, 2022
    Publication date: March 23, 2023
    Inventors: Martin TOLAR, John A. HEY, Petr KOCIS, Jeremy YU
  • Publication number: 20220096406
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.
    Type: Application
    Filed: September 17, 2021
    Publication date: March 31, 2022
    Inventors: Susan ABUSHAKRA, Aidan POWER, Martin TOLAR, John HEY, Jeremy YU, Petr KOCIS
  • Publication number: 20220087967
    Abstract: Provided herein is the use of a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating a disease characterized by amyloid and amyloid-like aggregates, e.g., Alzheimer's disease.
    Type: Application
    Filed: July 30, 2019
    Publication date: March 24, 2022
    Inventors: Petr Kocis, John Hey, Martin Tolar
  • Publication number: 20220062241
    Abstract: Methods of treating a disease characterized by amyloid aggregates are provided herein.
    Type: Application
    Filed: June 25, 2021
    Publication date: March 3, 2022
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Patent number: 11191742
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: December 7, 2021
    Assignee: Alzheon, Inc.
    Inventors: Susan Abushakra, Aidan Power, Martin Tolar, John Hey, Jeremy Yu, Petr Kocis
  • Publication number: 20210315847
    Abstract: Tramiprosate and derivatives thereof are provided herein for treating neurodegenerative disorders such as Alzheimer's disease (AD).
    Type: Application
    Filed: July 30, 2019
    Publication date: October 14, 2021
    Inventors: John Hey, Petr Kocis, Martin Tolar, Neil William Flanzraich
  • Patent number: 11077095
    Abstract: Methods of treating a disease characterized by amyloid aggregates are provided herein.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: August 3, 2021
    Assignee: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Patent number: 11053192
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: July 6, 2021
    Assignee: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20200347012
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: March 3, 2020
    Publication date: November 5, 2020
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20200101031
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Application
    Filed: September 13, 2019
    Publication date: April 2, 2020
    Inventors: Martin TOLAR, John A. HEY, Petr KOCIS, Jeremy YU
  • Patent number: 10590070
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: March 17, 2020
    Assignee: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20190374514
    Abstract: Methods of treating a disease characterized by amyloid aggregates are provided herein.
    Type: Application
    Filed: February 23, 2018
    Publication date: December 12, 2019
    Applicant: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Patent number: 10471029
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: November 12, 2019
    Assignee: Alzheon, Inc.
    Inventors: Martin Tolar, John A. Hey, Petr Kocis, Jeremy Yu
  • Publication number: 20180250249
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.
    Type: Application
    Filed: September 9, 2014
    Publication date: September 6, 2018
    Inventors: Susan Abushakra, Aidan Power, Martin Tolar, John Hey, Jeremy Yu, Petr Kocis
  • Publication number: 20180230091
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 16, 2018
    Inventors: Petr KOCIS, Martin TOLAR, John HEY
  • Publication number: 20170172952
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Application
    Filed: March 23, 2015
    Publication date: June 22, 2017
    Inventors: Martin TOLAR, John A. HEY, Petr KOCIS, Jeremy YU
  • Publication number: 20040092003
    Abstract: Inert, thermally and mechanically stable porous ceramic solid phase supports for use in solid phase synthesis of molecules wherein the porous ceramic solid supports can be used under a wide variety of reaction conditions and in synthesis methods, including but not limited to organic, regular, multiple parallel, or combinatorial organic synthesis on a solid phase. Methods of using the porous ceramic solid supports for solid phase synthesis of molecules, for solid phase synthesis of polypeptides or peptidomimetics, for generating combinatorial libraries of linkers, and for combinatorial synthesis of compounds, including small molecules and aromatic and heteroaromatic compounds.
    Type: Application
    Filed: June 23, 2003
    Publication date: May 13, 2004
    Applicant: Invitrogen Corporation
    Inventors: Egisto Boschetti, Petr Kocis
  • Publication number: 20020028520
    Abstract: Inert, thermally and mechanically stable porous ceramic solid phase supports for use in solid phase synthesis of molecules wherein the porous ceramic solid supports can be used under a wide variety of reaction conditions and in synthesis methods, including but not limited to organic, regular, multiple parallel, or combinatorial organic synthesis on a solid phase. Methods of using the porous ceramic solid supports for solid phase synthesis of molecules, for solid phase synthesis of polypeptides or peptidomimetics, for generating combinatorial libraries of linkers, and for combinatorial synthesis of compounds, including small molecules and aromatic and heteroaromatic compounds.
    Type: Application
    Filed: December 21, 2000
    Publication date: March 7, 2002
    Inventors: Egisto Boschetti, Petr Kocis