Abstract: A reaction pathfinder system can leverage historical chemical reaction data and determine a synthesis route in a reaction network. The reaction pathfinder system can account for various performance criteria of chemical reactions such as a highest yield for a molecule or a minimal number of reaction steps. A reaction pathfinder system receives a user request for a synthesis route including one of a user-specified molecule or a user-specified reaction. The reaction pathfinder system may then query a reaction network that has various synthesis routes and represents reactions of reactants to produce respective molecules. The reaction network may be composed of molecule nodes and reaction nodes. The reaction pathfinder system determines, using the reaction network, the synthesis route from the synthesis routes to fulfill the user's request.

Abstract: An adjustable steering column assembly for a vehicle comprises an upper shroud portion (8) which is adapted to receive a steering column (1, 2), a lower guide portion (7) which is adapted to support the shroud portion (8) and be secured to a mounting bracket (14) fixed relative to the chassis of the vehicle, a connecting pin (13) which projects through an elongate opening provided in the fixed bracket (14), an opening in the lower guide portion (7) and an elongate opening in the upper shroud portion (8), a toothed rail member (19) which is connected to the upper-shroud portion by an energy absorbing device (22), and an operating lever (17) which is operatively connected to the connecting pin (13).

Abstract: An adjustable steering column assembly for a vehicle comprises an upper shroud portion (8) which is adapted to receive a steering column (1, 2), a lower guide portion (7) which is adapted to support the shroud portion (8) and be secured to a mounting bracket (14) fixed relative to the chassis of the vehicle, a connecting pin (13) which projects through an elongate opening provided in the fixed bracket (14), an opening in the lower guide portion (7) and an elongate opening in the upper shroud portion (8), a toothed rail member (19) which is connected to the upper-shroud portion by an energy absorbing device (22), and an operating lever (17) which is operatively connected to the connecting pin (13).