Patents by Inventor Petr Y. Baranov

Petr Y. Baranov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenotype profile of human retinal progenitor cells
    Patent number: 11957719
    Abstract: The present invention relates to substantially homogenous populations of human retinal progenitor cells having the following positive surface markers: SSEA4, CD73, PTK7 and PSA-NCAM. The invention also relates to method for preparing such substantially homogeneous cell populations from human tissue using cell sorting techniques.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: April 16, 2024
    Assignee: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Petr Y. Baranov
  • LOW OXYGEN CULTURE CONDITIONS FOR MAINTAINING RETINAL PROGENITOR CELL MULTIPOTENCY
    Publication number: 20230313135
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: June 5, 2023
    Publication date: October 5, 2023
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • LOW OXYGEN CULTURE CONDITIONS FOR MAINTAINING RETINAL PROGENITOR CELL MULTIPOTENCY
    Publication number: 20210198625
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: December 23, 2020
    Publication date: July 1, 2021
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • Low oxygen culture conditions for maintaining retinal progenitor cell multipotency
    Patent number: 10947501
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: March 16, 2021
    Assignee: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • PHENOTYPE PROFILE OF HUMAN RETINAL PROGENITOR CELLS
    Publication number: 20200345785
    Abstract: The present invention relates to substantially homogenous populations of human retinal progenitor cells having the following positive surface markers: SSEA4, CD73, PTK7 and PSA-NCAM. The invention also relates to method for preparing such substantially homogeneous cell populations from human tissue using cell sorting techniques.
    Type: Application
    Filed: March 19, 2020
    Publication date: November 5, 2020
    Inventors: Michael J. Young, Petr Y. Baranov
  • Phenotype profile of human retinal progenitor cells
    Patent number: 10758572
    Abstract: The present invention relates to substantially homogenous populations of human retinal progenitor cells having the following positive surface markers: SSEA4, CD73, PTK7 and PSA-NCAM. The invention also relates to method for preparing such substantially homogeneous cell populations from human tissue using cell sorting techniques.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: September 1, 2020
    Assignee: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Petr Y. Baranov
  • GDNF INDUCTION FOR THE TREATMENT OF RETINAL DISORDERS
    Publication number: 20180228811
    Abstract: Methods and compositions for glial cell-derived neurotrophic factor (GDNF) induction in the eye, and for treatment and/or prevention of retinal disorders are described.
    Type: Application
    Filed: December 11, 2015
    Publication date: August 16, 2018
    Inventors: Dwight M. Morrow, Kathryn L. McCabe, Hong Lin, Petr Y. Baranov, Michael J. Young
  • LOW OXYGEN CULTURE CONDITIONS FOR MAINTAINING RETINAL PROGENITOR CELL MULTIPOTENCY
    Publication number: 20170335280
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: June 2, 2017
    Publication date: November 23, 2017
    Applicant: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • Low oxygen culture conditions for maintaining retinal progenitor cell multipotency
    Patent number: 9677050
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: June 13, 2017
    Assignee: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • Hybrid Matrix
    Publication number: 20150337260
    Abstract: The present invention relates to poly(caprolactone)-oligonucleotide surfaces for cell ware, and methods of use thereof for culturing, and differentiating cells.
    Type: Application
    Filed: January 10, 2014
    Publication date: November 26, 2015
    Inventors: Michael Young, Petr Y. Baranov
  • GENERATION OF PHOTORECEPTORS FROM HUMAN RETINAL PROGENITOR CELLS USING POLYCAPROLACTONE SUBSTRATES
    Publication number: 20150030658
    Abstract: The present invention relates to biocompatible compositions for transplantation into a sub-retinal space of the human eye. The compositions include a biodegradable polyester film, preferably a polycaprolactone (PCL) film, and a layer of human retinal progenitor cells. The compositions of the invention can be used as scaffolds for the treatment a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: January 22, 2013
    Publication date: January 29, 2015
    Inventors: Caio Regatieri, Petr Y. Baranov, Michael J. Young
  • PHENOTYPE PROFILE OF HUMAN RETINAL PROGENITOR CELLS
    Publication number: 20150017133
    Abstract: The present invention relates to substantially homogenous populations of human retinal progenitor cells having the following positive surface markers: SSEA4, CD73, PTK7 and PSA-NCAM. The invention also relates to method for preparing such substantially homogeneous cell populations from human tissue using cell sorting techniques.
    Type: Application
    Filed: February 15, 2013
    Publication date: January 15, 2015
    Inventors: Michael J. Young, Petr Y. Baranov
  • LOW OXYGEN CULTURE CONDITIONS FOR MAINTAINING RETINAL PROGENITOR CELL MULTIPOTENCY
    Publication number: 20140140965
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: October 17, 2013
    Publication date: May 22, 2014
    Applicant: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • Low oxygen culture conditions for maintaining retinal progenitor cell multipotency
    Patent number: 8563304
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: October 22, 2013
    Assignee: The Schepens Eye Research Institute
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov
  • GENERATION OF PHOTORECEPTORS FROM HUMAN RETINAL PROGENITOR CELLS USING POLYCAPROLACTONE SUBSTRATES
    Publication number: 20130189341
    Abstract: The present invention relates to biocompatible compositions for transplantation into a sub-retinal space of the human eye. The compositions include a biodegradable polyester film, preferably a polycaprolactone (PCL) film, and a layer of human retinal progenitor cells. The compositions of the invention can be used as scaffolds for the treatment a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: January 23, 2012
    Publication date: July 25, 2013
    Inventors: Caio Regatieri, Petr Y. Baranov, Michael J. Young
  • LOW OXYGEN CULTURE CONDITIONS FOR MAINTAINING RETINAL PROGENITOR CELL MULTIPOTENCY
    Publication number: 20120321593
    Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.
    Type: Application
    Filed: June 14, 2011
    Publication date: December 20, 2012
    Applicant: THE SCHEPENS EYE RESEARCH INSTITUTE
    Inventors: Michael J. Young, Budd A. Tucker, Petr Y. Baranov