Patents by Inventor Petra Boyle

Petra Boyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human anti-TNF antibodies
    Patent number: 5654407
    Abstract: Human monoclonal antibodies (mAbs) which bind to human TNF.alpha. are disclosed. Autoantibodies of both the IgM and IgG isotypes are disclosed. A preferred human monoclonal antibody is known as B5 (F78-1A10-B5 mAb) and it binds to recombinant human TNF.alpha. (rhTNF.alpha.) in ELISA format with a titer comparable to three high affinity neutralizing mouse mAbs. It also binds to cell surface TNF.alpha. and prevents TNF.alpha. secretion by human monocyte cell lines.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: August 5, 1997
    Assignee: Bayer Corporation
    Inventors: Petra Boyle, Gayle D. Wetzel, Kenneth J. Lembach