Patents by Inventor Petra Franzen

Petra Franzen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies which bind specifically to activin receptor like kinase 3
    Patent number: 8080639
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-?-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 20, 2011
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Activin receptor-like kinase-1 proteins having serine-threonine kinase domains
    Patent number: 7932351
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-beta-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: April 26, 2011
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Activin receptor-like kinases, proteins having serine threonine kinase domains and their use
    Publication number: 20100330657
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-?-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Application
    Filed: October 31, 2007
    Publication date: December 30, 2010
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Antibodies which bind specifically to activin receptor like kinases
    Patent number: 7592428
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-?-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: September 22, 2009
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Activin receptor-like kinases, proteins having serine threonine kinase domains and their use
    Publication number: 20070203329
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-beta-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Application
    Filed: January 23, 2007
    Publication date: August 30, 2007
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Antibodies which bind specifically to activin receptor-like kinases
    Patent number: 6982319
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-?-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: January 3, 2006
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • PARG, a GTPase activating protein which interacts with PTPL1
    Publication number: 20030166232
    Abstract: The invention describes nucleic acids encoding the PARG protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods and products for using such nucleic acids and polypeptides also are provided.
    Type: Application
    Filed: June 21, 2002
    Publication date: September 4, 2003
    Inventors: Jan Saras, Petra Franzen, Pontus Aspenstrom, Ulf Hellman, Leonel Jorge Gonez, Carl-Henrik Heldin
  • PARG, a GTPase activating protein which interacts with PTPL1
    Patent number: 6475775
    Abstract: The invention describes nucleic acids encoding the PARG protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods and products for using such nucleic acids and polypeptides also are provided.
    Type: Grant
    Filed: May 8, 2000
    Date of Patent: November 5, 2002
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Jan Saras, Petra Franzén, Pontus Aspenström, Ulf Hellman, Leonel Jorge Gonez, Carl-Henrik Heldin
  • Antibodies which bind specifically to activin receptor like kinases
    Publication number: 20020123139
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel Proteins have activin/TGF-&bgr;-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Application
    Filed: July 11, 2001
    Publication date: September 5, 2002
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Isolated nucleic acid molecules which encode activin-receptor like kinases, expression vectors and cells containing these
    Patent number: 6331621
    Abstract: The invention involves nucleic acid molecules which encode activin like kinases, expression vectors, and cell lines.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: December 18, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Activin receptor-like kinases, proteins having serine threonine kinase domains and polynucleotides encoding same
    Patent number: 6316217
    Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-&bgr;-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
    Type: Grant
    Filed: October 30, 1995
    Date of Patent: November 13, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Activin like receptor--Isolated kinase proteins ALK-2, ALK-4, ALK-5, and nucleic acid molecules encoding them
    Patent number: 6271365
    Abstract: The invention involves three members of the activin like receptor kinase family, and the nucleic acids encoding these.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: August 7, 2001
    Assignee: Ludwig Institute For Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Activin receptor-like kinases, ALK-3 and ALK-6, and nucleic acids encoding them
    Patent number: 6207814
    Abstract: The invention relates to two members of the receptor family referred to as activin-like kinases. These two members are referred to as ALK-3 and ALK-6. The proteins have activin/TGF-&bgr; type I receptor functionality, and may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain V1B, and/or a GTKRYM sequence in subdomain VIII.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: March 27, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Kohei Miyazono, Peter ten Dijke, Petra Franzen, Hidetoshi Yamashita, Carl-Henrik Heldin
  • Isolated nucleic acid molecules encoding PARG, a GTPase activating protein which interacts with PTPL1
    Patent number: 6083721
    Abstract: The invention describes nucleic acids encoding the PARG protein, including fragments and biologically functional variants thereof. Also included are polypeptides and fragments thereof encoded by such nucleic acids, and antibodies relating thereto. Methods and products for using such nucleic acids and polypeptides also are provided.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: July 4, 2000
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Jan Saras, Petra Franzen, Pontus Aspenstrom, Ulf Hellman, Leonel Jorge Gonez, Carl-Henrik Heldin