Patents by Inventor Petra Simon

Petra Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCING THE EFFECT OF CAR-ENGINEERED T CELLS BY MEANS OF NUCLEIC ACID VACCINATION
    Publication number: 20180140634
    Abstract: The present invention generally embraces the treatment of diseases by targeting cells expressing an antigen on the cell surface. In particular the invention relates to a method for stimulating, priming and/or expanding in vivo T cells genetically modified to express a chimeric antigen receptor (CAR) targeted to an antigen, comprising contacting the T cells with the antigen or a variant thereof in vivo. In one embodiment, the antigen or variant thereof is provided by administering a nucleic acid encoding the antigen or variant thereof.
    Type: Application
    Filed: May 9, 2016
    Publication date: May 24, 2018
    Inventors: Ugur SAHIN, Katharina REINHARD, Petra SIMON, Karolina Anna MROZ, Kathleen HOBOHM
  • Antigen-Specific T Cell Receptors and T Cell Epitopes
    Publication number: 20170112911
    Abstract: The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.
    Type: Application
    Filed: December 28, 2016
    Publication date: April 27, 2017
    Inventors: Ugur Sahin, Ozlem Tureci, Petra Simon, Tana Omokoko
  • Antigen-specific T cell receptors and T cell epitopes
    Patent number: 9586997
    Abstract: The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: March 7, 2017
    Assignees: BioNtech Cell & Gene Therapies GmbH, Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz gemeinnutzige GmbH
    Inventors: Ugur Sahin, Ozlem Tureci, Petra Simon, Tana Omokoko
  • CLAUDIN-6-SPECIFIC IMMUNORECEPTORS AND T CELL EPITOPES
    Publication number: 20170015720
    Abstract: The present invention provides Claudin-6-specific immunoreceptors (T cell receptors and artificial T cell receptors (chimeric antigen receptors; CARs)) and T cell epitopes which are useful for immunotherapy.
    Type: Application
    Filed: March 30, 2015
    Publication date: January 19, 2017
    Applicants: Biontech Cell & Gene thrapies GMBH, Tron - Translationale Onkologie Ander Universitata tsmedizin Der Johannes Gutenberg-Universitat Main, Univeritatsmedizin der Johannes Gutenberg-, Ganymed Pharmceuticals AG
    Inventors: Ugur SAHIN, Özlem TÜRECI, Petra SIMON, Tana OMOKOKO, Holger HOFF, Ralf-Holger VOSS, Andrea BREITKREUZ, Kathleen HOBOHM, Karolina, Anna , MROZ
  • METHOD AND KIT FOR DETERMINING WHETHER A SUBJECT SHOWS AN IMMUNE RESPONSE
    Publication number: 20160265050
    Abstract: The present invention relates to a kit and a method for determining whether a subject shows an immune response against an antigen.
    Type: Application
    Filed: October 24, 2014
    Publication date: September 15, 2016
    Inventors: Ugur SAHIN, Michael SCHÄFER, Marta Magdalena FARYNA, Tana OMOKOKO, Lisa HEBICH, Petra SIMON, Annett REICHARDT, Özlem YILDIZ
  • Antigen-Specific T Cell Receptors and T Cell Epitopes
    Publication number: 20130273647
    Abstract: The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.
    Type: Application
    Filed: September 19, 2011
    Publication date: October 17, 2013
    Applicants: BIONTECH AG, TRON- Translationale Onkologie an der Universi- ttttatsmedzin der Johannes Gutenberg- UNiversitat, Universitatsmedizin der Johannes Gutterberg- Universital MAinz
    Inventors: Ugur Sahin, Ozlem Tureci, Petra Simon, Tana Omokoko