Patents by Inventor Petra Van Kuik-Romeijn

Petra Van Kuik-Romeijn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecules for targeting compounds to various selected organs, tissues or tumor cells
    Patent number: 8609065
    Abstract: The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat neuronal or neuromuscular disease, or a pathology of the brain, or a tumor of neuronal or neuroectodermal origin, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the brain cells or neuronal cells, or by the tumor cells of neuronal or neuroectodermal origin. The invention also provides a method of identifying and measuring neurite growth in neuronal cells.
    Type: Grant
    Filed: January 8, 2010
    Date of Patent: December 17, 2013
    Assignee: Prosensa Technologies B.V.
    Inventors: Petra Van Kuik-Romeijn, Gerard Johannes Platenburg
  • Molecules for targeting compounds to various selected organs or tissues
    Patent number: 8519097
    Abstract: The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: August 27, 2013
    Assignee: Prosena Technologies B.V.
    Inventors: Johannes Antonius Heemskerk, Judith Christina Theodora Van Deutekom, Petra Van Kuik-Romeijn, Gerard Johannes Platenburg
  • MOLECULES FOR TARGETING COMPOUNDS TO VARIOUS SELECTED ORGANS OR TISSUES
    Publication number: 20120322724
    Abstract: The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.
    Type: Application
    Filed: August 7, 2012
    Publication date: December 20, 2012
    Applicant: Prosensa Technologies B.V.
    Inventors: Johannes Antonius Heemskerk, Judith Christina Theodora Van Deutekom, Petra Van Kuik-Romeijn, Gerard Johannes Platenburg
  • Molecules for targeting compounds to various selected organs or tissues
    Patent number: 8268962
    Abstract: The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: September 18, 2012
    Assignee: Prosensa Technologies B.V.
    Inventors: Johannes Antonius Heemskerk, Judith Christina Theodora Van Deutekom, Petra Van Kuik-Romeijn, Gerard Johannes Platenburg
  • Novel mRNA splice variant of the doublecortin-like kinase gene and its use in cancer diagnosis and therapy
    Publication number: 20110020430
    Abstract: Methods for treating neuroblastoma in a subject are provided. The methods include administering to the subject nucleic acid that is capable of causing a significant reduction of the amount of doublecortin like protein (DCL) in the subject. The nucleic acids include antisense oligonucleotides and small interfering RNA.
    Type: Application
    Filed: May 24, 2010
    Publication date: January 27, 2011
    Applicants: PROSENSA B.V., Universiteit Leiden
    Inventors: Erno VREUGDENHIL, Petra Van Kuik-Romeijn
  • MOLECULES FOR TARGETING COMPOUNDS TO VARIOUS SELECTED ORGANS OR TISSUES
    Publication number: 20100184948
    Abstract: The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.
    Type: Application
    Filed: January 11, 2010
    Publication date: July 22, 2010
    Applicant: PROSENSA TECHNOLOGIES B.V.
    Inventors: JOHANNES ANTONIUS HEEMSKERK, JUDITH CHRISTINA THEODORA VAN DEUTEKOM, PETRA VAN KUIK-ROMEIJN, GERARD JOHANNES PLATENBURG
  • MOLECULES FOR TARGETING COMPOUNDS TO VARIOUS SELECTED ORGANS, TISSUES OR TUMOR CELLS
    Publication number: 20100184947
    Abstract: The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat neuronal or neuromuscular disease, or a pathology of the brain, or a tumor of neuronal or neuroectodermal origin, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the brain cells or neuronal cells, or by the tumor cells of neuronal or neuroectodermal origin. The invention also provides a method of identifying and measuring neurite growth in neuronal cells.
    Type: Application
    Filed: January 8, 2010
    Publication date: July 22, 2010
    Applicant: Prosensa Technologies B.V.
    Inventors: Petra Van Kuik-Romeijn, Gerard Johannes Platenburg
  • mRNA splice variant of the doublecortin-like kinase gene and its use in cancer diagnosis and therapy
    Patent number: 7754871
    Abstract: The present invention relates to novel nucleic acid and protein molecules and their use in neuroblastoma therapy and diagnosis.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: July 13, 2010
    Assignees: Prosensa B.V., Universiteit Leiden
    Inventors: Erno Vreugdenhil, Petra Van Kuik-Romeijn
  • Novel mRNA splice variant of the doublecortin-like kinase gene and its use in cancer diagnosis and therapy
    Publication number: 20060019924
    Abstract: The present invention relates to novel nucleic acid and protein molecules and their use in neuroblastoma therapy and diagnosis.
    Type: Application
    Filed: July 22, 2005
    Publication date: January 26, 2006
    Applicants: PROSENA B.V., Universiteit Leiden
    Inventors: Erno Vreugdenhil, Petra Van Kuik-Romeijn