Patents by Inventor Petra Ziegler

Petra Ziegler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide sequences coding for proteins involved in the biosynthesis of L-serine, an improved method for the microbial production of L-serine and a genetically modified microorganism suitable therefor
    Patent number: 7083952
    Abstract: The present invention relates to nucleotide sequences of coryneform bacteria, coding for proteins involved in the bio-synthesis of L-serine and to methods for the isolation thereof. The invention further relates to an improved method for the production of L-serine. In addition, the present invention relates to the use of L-serine in the food, animal feed and/or pharmaceutical industries or in human medicine.
    Type: Grant
    Filed: August 21, 2002
    Date of Patent: August 1, 2006
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Petra Peters-Wendisch
  • Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
    Patent number: 6913909
    Abstract: The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out: a) Fermentation of microorganisms in which at least the thrE gene is amplified (overexpressed), optionally in combination with further genes, b) Enrichment of the L-threonine in the medium or in the cells of the microorganisms, and c) Isolation of the L-threonine.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: July 5, 2005
    Assignee: Degussa AG
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach
  • Nucleotide sequences coding for proteins involved in the biosynthesis of L-serine, an improved method for the microbial production of L-serine and a genetically modified microorganism suitable therefor
    Publication number: 20040101837
    Abstract: The present invention relates to nucleotide sequences of coryneform bacteria, coding for proteins involved in the bio-synthesis of L-serine and to methods for the isolation thereof. The invention further relates to an improved method for the production of L-serine. In addition, the present invention relates to the use of L-serine in the food, animal feed and/or pharmaceutical industries or in human medicine.
    Type: Application
    Filed: August 21, 2002
    Publication date: May 27, 2004
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Petra Peters-Wendisch
  • Process for the fermentative preparation of L-amino acids using coryneform bacteria
    Patent number: 6596516
    Abstract: A process for the preparation of L-amino acids, in which the following steps are carried out, a) fermenting the desired L-amino acid-producing bacteria in which at least the glyA gene is attenuated, in particular by removal of the natural promoter, and optionally b) concentrating the desired product in the medium or in the cells of the bacteria and c) isolating the L-amino acid, and optionally bacteria in which further genes of the biosynthesis pathway of the desired L-amino acid are additionally amplified are employed, or bacteria in which the metabolic pathways which reduce the formation of the desired L-amino acid are at least partly eliminated are employed, and nucleotide sequences of the lacI-tac-5′glyA or lacI-tac-glyA unit.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: July 22, 2003
    Assignees: Degussa AG, Forschungszentrum Jülich GmbH
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach, Walter Pfefferle
  • Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
    Publication number: 20030049802
    Abstract: The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out:
    Type: Application
    Filed: September 14, 2001
    Publication date: March 13, 2003
    Applicant: Degusa Huls Aktiengeselschaft
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach
  • New nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
    Publication number: 20020168731
    Abstract: The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out:
    Type: Application
    Filed: February 15, 2001
    Publication date: November 14, 2002
    Applicant: Degussa-Huls AG
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach
  • Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
    Publication number: 20020146781
    Abstract: The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out:
    Type: Application
    Filed: September 27, 2001
    Publication date: October 10, 2002
    Applicant: Degusa Huls Aktiengeselschaft
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach
  • New nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
    Publication number: 20020107378
    Abstract: The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out:
    Type: Application
    Filed: September 14, 2001
    Publication date: August 8, 2002
    Applicant: Degusa Huls Aktiengeselschaft
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach
  • Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria
    Patent number: 6410705
    Abstract: The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: June 25, 2002
    Assignee: Degussa Huls Aktiengesellschaft
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach
  • Process for the fermentative preparation of L-amino acids using coryneform bacteria
    Publication number: 20020072098
    Abstract: A process for the preparation of L-amino acids, in which the following steps are carried out,
    Type: Application
    Filed: December 8, 2000
    Publication date: June 13, 2002
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach, Walter Pfefferle