Abstract: Embodiments described herein derive improvements to a collimator model of a multi-leaf collimator (MLC) for a dose calculation source model. The MLC has movable leaves formed of an attenuating material for a beam of radiation. The collimation model includes a 3D geometric model of the MLC. The system determines a plurality of attenuation lengths at leaf of the MLC in attenuating the beam of radiation. The beam of radiation includes a plurality of beam segments, and the plurality of attenuation lengths at leaf may be based on distance that the beamlet travels in leaf along respective beam segments. The system retrieves pre-calculated beam spectrum data for the beam of radiation, and may receive data representing the input spectrum for the beam of radiation. The system applies these data to calculate adjustments to the dose calculation source model to take into account beam hardening along the MLC geometry.

Abstract: Embodiments described herein provide for training a local neural network model that receives a first data set corresponding to parameters of a radiation therapy delivery system for delivering a radiation field to a phantom. The neural network model has been trained to determine the quantity of radiation delivered to a plurality of volume elements of the phantom based on the parameters of the first data set. The local neural network model receives local dose calculation parameters, such as total energy released per mass (TERMA) values and density values, for each voxel grid element of a high resolution voxel grid of the phantom. In an embodiment, each voxel grid element includes a central voxel and a plurality of neighboring voxels. The processor applies the neural network model to the TERMA values and the density values of the neighboring voxels to determine the quantity of radiation delivered to the central voxel.

Abstract: A method of calculating radiation dose includes dosimetric projection of a collimator geometry. The method includes defining a three-dimensional (3D) geometry of a collimating device which defines an aperture configured to allow a radiation beam passing through, projecting the collimating device along the radiation beam into a two-dimensional (2D) geometry in a plane, calculating dosimetric opacity values of the collimating device at locations adjacent to the aperture based on the 3D geometry of the collimating device, and calculating transport of the radiation beam through the collimating device based on the 2D geometry projected in the plane and using the dosimetric opacity values of the collimating device at the locations adjacent to the aperture.

Abstract: A method of calculating radiation dose includes dosimetric projection of a collimator geometry. The method includes defining a three-dimensional (3D) geometry of a collimating device which defines an aperture configured to allow a radiation beam passing through, projecting the collimating device along the radiation beam into a two-dimensional (2D) geometry in a plane, calculating dosimetric opacity values of the collimating device at locations adjacent to the aperture based on the 3D geometry of the collimating device, and calculating transport of the radiation beam through the collimating device based on the 2D geometry projected in the plane and using the dosimetric opacity values of the collimating device at the locations adjacent to the aperture.