Patents by Inventor Petrus Bekker

Petrus Bekker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating pancreatic cancer
    Patent number: 11890276
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Grant
    Filed: August 23, 2021
    Date of Patent: February 6, 2024
    Assignee: CHEMOCENTRYX, INC.
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • Method of treating C3 glomerulopathy
    Patent number: 11779576
    Abstract: Methods of treating a human suffering from or susceptible to C3 glomerulopathy comprising administering to the human an effective amount of a C5aR antagonist are provided.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: October 10, 2023
    Assignee: CHEMOCENTRYX, INC.
    Inventor: Petrus Bekker
  • C5aR INHIBITOR REDUCTION OF URINARY sCD163
    Publication number: 20230105869
    Abstract: Provided herein are methods of treating ANCA-associated vasculitis (AAV) in individuals in need thereof comprising administering a complement component 5a receptor (C5aR) antagonist. Also provided herein are methods of treating a ANCA-associated vasculitis (AAV) with renal involvement in an individual in need thereof comprising administering a complement component 5a receptor (C5aR) antagonist to the individual if the individual exhibits an elevated urinary soluble CD163 (sCD163) to creatinine ratio compared to individuals without AAV. In some embodiments, the complement component 5a receptor (C5aR) antagonist is avacopan.
    Type: Application
    Filed: July 29, 2022
    Publication date: April 6, 2023
    Inventors: Jun DENG, Thomas J. SCHALL, Petrus BEKKER
  • METHOD OF TREATING C3 GLOMERULOPATHY
    Publication number: 20220354837
    Abstract: Methods of treating a human suffering from or susceptible to C3 glomerulopathy comprising administering to the human an effective amount of a C5aR antagonist are provided.
    Type: Application
    Filed: February 14, 2022
    Publication date: November 10, 2022
    Inventor: Petrus BEKKER
  • DOSING AND EFFECT OF C5a ANTAGONIST WITH ANCA-ASSOCIATED VASCULITIS
    Publication number: 20220296576
    Abstract: The present disclosure provides methods for treating ANCA-associate vasculitis in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of avacopan: or a pharmaceutically acceptable salt thereof, such that the level of plasma complement factor Bb, C3a, or C5a does not significantly change in the human upon treatment.
    Type: Application
    Filed: November 4, 2021
    Publication date: September 22, 2022
    Inventors: Jun DENG, Petrus BEKKER, Jan HILLSON
  • Method of treating C3 glomerulopathy
    Patent number: 11285138
    Abstract: Methods of treating a human suffering from or susceptible to C3 glomerulopathy comprising administering to the human an effective amount of a C5aR antagonist are provided.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: March 29, 2022
    Assignee: ChemoCentryx, Inc.
    Inventor: Petrus Bekker
  • METHODS OF TREATING PANCREATIC CANCER
    Publication number: 20210401816
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Application
    Filed: August 23, 2021
    Publication date: December 30, 2021
    Inventors: Petrus BEKKER, Shichang MIAO, Israel CHARO, Tom SCHALL
  • Dosing and effect of C5a antagonist with ANCA-associated vasculitis
    Patent number: 11191756
    Abstract: The present disclosure provides methods for treating ANCA-associate vasculitis in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of avacopan: or a pharmaceutically acceptable salt thereof, such that the level of plasma complement factor Bb, C3a, or C5a does not significantly change in the human upon treatment.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: December 7, 2021
    Assignee: ChemoCentryx, Inc.
    Inventors: Jun Deng, Petrus Bekker, Jan Hillson
  • Methods of treating pancreatic cancer
    Patent number: 11116756
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: September 14, 2021
    Assignee: ChemoCentryx, Inc.
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • METHODS OF TREATING PANCREATIC CANCER
    Publication number: 20200179359
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Application
    Filed: February 14, 2020
    Publication date: June 11, 2020
    Inventors: Petrus Bekker, Shichang MIAO, Israel CHARO, Tom SCHALL
  • Methods of treating pancreatic cancer
    Patent number: 10583131
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: March 10, 2020
    Assignee: ChemoCentryx, Inc.
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • DOSING AND EFFECT OF C5a ANTAGONIST WITH ANCA-ASSOCIATED VASCULITIS
    Publication number: 20190374524
    Abstract: The present disclosure provides methods for treating ANCA-associate vasculitis in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of avacopan: or a pharmaceutically acceptable salt thereof, such that the level of plasma complement factor Bb, C3a, or C5a does not significantly change in the human upon treatment.
    Type: Application
    Filed: June 6, 2019
    Publication date: December 12, 2019
    Inventors: Jun DENG, Petrus BEKKER, Jan HILLSON
  • METHODS OF TREATING PANCREATIC CANCER
    Publication number: 20190350911
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 21, 2019
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • Methods of treating pancreatic cancer
    Patent number: 10398685
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: September 3, 2019
    Assignee: ChemoCentryx, Inc.
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • METHOD OF TREATING C3 GLOMERULOPATHY
    Publication number: 20190201388
    Abstract: Methods of treating a human suffering from or susceptible to C3 glomerulopathy comprising administering to the human an effective amount of a C5aR antagonist are provided.
    Type: Application
    Filed: November 8, 2018
    Publication date: July 4, 2019
    Inventor: Petrus BEKKER
  • METHODS OF TREATING PANCREATIC CANCER
    Publication number: 20190167650
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Application
    Filed: February 4, 2019
    Publication date: June 6, 2019
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • C5aR INHIBITOR REDUCTION OF URINARY sCD163
    Publication number: 20190134020
    Abstract: Provided herein are methods of treating ANCA-associated vasculitis (AAV) in individuals in need thereof comprising administering a complement component 5a receptor (C5aR) antagonist. Also provided herein are methods of treating a ANCA-associated vasculitis (AAV) with renal involvement in an individual in need thereof comprising administering a complement component 5a receptor (C5aR) antagonist to the individual if the individual exhibits an elevated urinary soluble CD163 (sCD163) to creatinine ratio compared to individuals without AAV. In some embodiments, the complement component 5a receptor (C5aR) antagonist is avacopan.
    Type: Application
    Filed: October 30, 2018
    Publication date: May 9, 2019
    Inventors: Jun DENG, Thomas J. SCHALL, Petrus BEKKER
  • Method of treating pancreatic cancer
    Patent number: 10251888
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: April 9, 2019
    Assignee: ChemoCentryx, Inc.
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • Method of treating pancreatic cancer
    Patent number: 10195188
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: February 5, 2019
    Assignee: ChemoCentryx, Inc.
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall
  • METHOD OF TREATING PANCREATIC CANCER
    Publication number: 20170368043
    Abstract: The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or regulating signaling proteins in patients comprising administering compounds and pharmaceutical combinations as described herein.
    Type: Application
    Filed: September 1, 2017
    Publication date: December 28, 2017
    Inventors: Petrus Bekker, Shichang Miao, Israel Charo, Tom Schall