Patents by Inventor Petrus Johannes Lenting

Petrus Johannes Lenting has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Factor VIII polypeptide having factor VIII:C activity
    Patent number: 8546332
    Abstract: Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: October 1, 2013
    Assignee: Stichting Sanquin Bloedvoorziening
    Inventors: Petrus Johannes Lenting, Jan Aart Van Mourik, Koenraad Mertens, Hans Pannekoek, Peter Turecek, Hans-Peter Schwarz, Friedrich Scheiflinger
  • FACTOR VIII POLYPEPTIDE HAVING FACTOR VIII:C ACTIVITY
    Publication number: 20110118188
    Abstract: Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
    Type: Application
    Filed: February 19, 2009
    Publication date: May 19, 2011
    Applicant: STICHTING SANQUIN BLOEDVOORZIENING
    Inventors: PETRUS JOHANNES LENTING, JAN AART VAN MOURIK, KOENRAAD MERTENS, HANS PANNEKOEK, PETER TURECEK, HANS-PETER SCHWARZ, FRIEDRICH SCHEIFLINGER
  • Factor VIII polypeptide having factor VIII:C activity
    Patent number: 7544660
    Abstract: Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: June 9, 2009
    Assignee: Stichting Sanquin Bloedvoorziening
    Inventors: Petrus Johannes Lenting, Jan Aart Van Mourik, Koenraad Mertens, Hans Pannekoek, Peter Turecek, Hans-Peter Schwarz, Friedrich Scheiflinger
  • Factor VII polypeptide having factor VII:C activity
    Patent number: 6919311
    Abstract: Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: July 19, 2005
    Assignee: Stichting Sanquin Bloedvoorziening
    Inventors: Petrus Johannes Lenting, Jan Aart Van Mourik, Koenraad Mertens, Hans Pannekoek, Peter Turecek, Hans-Peter Schwarz, Friedrich Scheiflinger
  • Factor IX binding peptides, derived from factor VIII and their use as inhibitors of blood coagulation
    Patent number: 6284871
    Abstract: The present invention relates to biologically active peptides which specifically inhibit the Factor IX-dependent pathway of blood coagulation. These peptides are based on a specific motif which represents a sequence of Factor VIII (amino acid 1811-1818) involved in binding to activated Factor IX as well as to the intact Factor IX zymogen. Binding of said peptides to Factor IX or activated derivatives thereof effectively inhibits complex assembly with Factor VIII. These peptides thereby specifically interfere in the Factor IX-dependent pathway of thrombin formation, while leaving other haemostatic pathways unaffected. By virtue of this unique specificity, the peptides of this invention are particularly useful in novel pharmaceutical compositions for the treatment of thrombotic disorders.
    Type: Grant
    Filed: December 9, 1997
    Date of Patent: September 4, 2001
    Assignee: Stiching Centraal Laboratorium van de Bloedtransfusiedienst van Nederlandse Rode Kruis
    Inventors: Koenraad Mertens, Petrus Johannes Lenting