Abstract: An optical assembly including light sources emitting light beams having multiple wavelengths; fiber combiner(s) arranged to combine light beams into combined beam, light beams enter fiber combiner(s); optical homogenizer(s), combined beam having non-homogenous intensity profile received at third end and combined beam having homogeneous intensity profile exits at fourth end; first optical element(s) second optical element(s), between optical homogenizer(s) and light guide(s), first optical element(s) and second optical(s) element collectively steer combined beam towards light guide(s), when optical assembly in use, second optical element(s) is adjustable to steer combined beam; first actuator(s) coupled to first optical element(s); controller coupled to first actuator(s), controller generate first signal controlling first actuator(s) that combined beam is steered by first optical element(s) also causing vibration of first optical element(s) at randomized pattern.

Abstract: A hyperspectral detection approach is used in combination with narrow linewidth illumination for fluorescence excitation. A more efficient fluorophores excitation and image capturing may be provided, and thus high-quality data for subsequent hyperspectral analysis may be obtained. An apparatus, a method, a system and a computer program are disclosed.

Abstract: Disclosed is an apparatus and method for fluorescence excitation and detection. The apparatus comprises one or more light sources for providing excitation light for fluorescence excitation at an observation spot along an optical axis for excitation, an optical collection element for collecting fluorescence light generated by the excitation light at two or more different observation spots into two or more different measurement channels with an optical axis for collecting non-parallel to the optical axis for excitation of each of the one or more light sources, and, for each of the two or more measurement channels and thereby for each of the two or more observation spots, a dedicated optical detector for detecting fluorescence from the fluorescence light collected by the optical collection element.

Abstract: A method and a system for light-activated drug delivery. An optical probe is coupled to a tissue for transmitting light signals to the tissue for actuating and/or monitoring drug delivery with a multi-phase method for drug delivery. A first light signal is transmitted through the optical probe for actuating and/or monitoring the drug delivery and a second light signal having a different wavelength is transmitted, simultaneously with the first light signal, through the optical probe for actuating and/or monitoring the drug delivery.

Abstract: Various example embodiments relate to guiding a user of a medical laser device by voice based on monitored treatment data. In addition, a voice control procedure for operating the medical laser device with improved safety is provided. Improved usage of the medical laser device is enabled also in situations where there is a limited visual and physical access to control the device. An apparatus, a method, a theranostic system and a computer program are disclosed.

Abstract: A theranostic laser system for light-activated drug delivery and monitoring. The system includes a light source, a light receiver and a coupler for simultaneously coupling a first optical delivery fiber to the light source for transmitting one or more first downstream light signals from the light source to the first optical delivery fiber and to the light receiver for transmitting one or more first upstream light signals from the first optical delivery fiber to the light receiver.

Abstract: A method for re-configuring a biomedical laser device. The biomedical laser device is pre-configured to be operable in one or more operational modes, and is provided with set of operational parameters that are employed for at least one of: given medical procedure, given medical treatment, activation of given drug, illumination of given dye. The method includes collecting information indicative of light output properties of biomedical laser device measured during given operational mode; detecting deviation in measured light output properties with respect to predefined light output properties for given operational mode; determining new set of operational parameters that are to be employed for at least one of: new medical procedure, new medical treatment, activation of new drug, illumination of new dye; and sending new set of operational parameters to biomedical laser device for re-configuring biomedical laser device to be operable in a new operational mode.

Abstract: A method for operating a biomedical laser. The method includes providing the biomedical laser having a first range of operational parameters; providing a second range of operational parameters for the biomedical laser; activating the biomedical laser to operate within the second range of operational parameters; identifying a need for a change in operational parameters of the biomedical laser; and triggering an action based on the identified need. The action includes providing a third range of operational parameters for the biomedical laser and activating the biomedical laser to operate within the third range of operational parameters; and de-activating a range of operational parameters. The second and third range of operational parameters is within the first range of operational parameters.

Abstract: A method for re-configuring a biomedical laser device. The biomedical laser device is pre-configured to be operable in one or more operational modes, and is provided with set of operational parameters that are employed for at least one of: given medical procedure, given medical treatment, activation of given drug, illumination of given dye. The method includes collecting information indicative of light output properties of biomedical laser device measured during given operational mode; detecting deviation in measured light output properties with respect to predefined light output properties for given operational mode; determining new set of operational parameters that are to be employed for at least one of: new medical procedure, new medical treatment, activation of new drug, illumination of new dye; and sending new set of operational parameters to biomedical laser device for re-configuring biomedical laser device to be operable in a new operational mode.

Abstract: A method for operating a biomedical laser. The method includes providing the biomedical laser having a first range of operational parameters; providing a second range of operational parameters for the biomedical laser; activating the biomedical laser to operate within the second range of operational parameters; identifying a need for a change in operational parameters of the biomedical laser; and triggering an action based on the identified need. The action includes providing a third range of operational parameters for the biomedical laser and activating the biomedical laser to operate within the third range of operational parameters; and de-activating a range of operational parameters. The second and third range of operational parameters is within the first range of operational parameters.

Abstract: A method and a system for configuring a first biomedical laser. The method includes providing a first set of operational parameters; operating the first biomedical laser using the first set of operational parameters; measuring an operational response of the first biomedical laser; measuring a light output properties of the first biomedical laser; analyzing the measured light output properties and the operational response; and triggering an action based on the analysis.