Abstract: A method for modulating the electrical synchronization of the cerebral cortex within safe limits by computing the orientation of the applied currents with respect to the orientation of the cortical surface and thus cortical columns. Ongoing electroencephalographic monitoring, including the synchronization of induced with stimulating currents, may confirm the precision and safety of the applied currents.

Abstract: An electric Markov blanket (eMb) system and method for establishing a Brain-Computer Criticality Bridge (BCCB) are disclosed. Electrophysiological signals are acquired from an organism, decomposed to obtain cross-frequency coupling metrics indexing excitatory-inhibitory criticality, and assembled into a Criticality Vector that fully characterizes the organism's electric Markov blanket. The Criticality Vector may be stored, analyzed, reproduced in vivo via patterned neuromodulation, or instantiated in silico or other informatic medium to create a personal neuromorphic emulation. Embodiments include ethical-control mechanisms ensuring user sovereignty and safety. The invention enables clinical interventions, cognitive enhancement, and personal-identity preservation.

Abstract: A method for personal neuromorphic emulation. The method may include constructing a computerized anatomical network model of neurons in the brain, the anatomical network model defining adjustably weighted connections between the modeled neurons and producing EEG signals as outputs; taking first hdEEG data from the subject while the subject's brain is awake and performing one or more first intellectual tasks; and adjusting the weights of the weighted connections of the anatomical network model so as to drive the EEG signal outputs of the anatomical network model toward the first hdEEG data.

Abstract: A method for modulating the electrical synchronization of the cerebral cortex within safe limits by computing the orientation of the applied currents with respect to the orientation of the cortical surface and thus cortical columns. Ongoing electroencephalographic monitoring, including the synchronization of induced with stimulating currents, may confirm the precision and safety of the applied currents.

Abstract: A method for achieving super-resolution in localizing electrical fields measured at the head surface with electroencephalography through a generative model of the cerebral cortex that has a very high resolution of cortical surface dipoles constructed from the known properties of human cerebral cortex and adapted to optimize the Bayesian explanation the individual's cortical surface electrical fields. The iterative optimization of the prior (generative) with the posterior (observed) fields with extensive data from extended recordings provides a probabilistic estimation of the individual's functional brain activity that can be used to train artificial neural network approximations of the individual's mental activity.

Abstract: A method for controlling the behavior of Large Language Models (LLMs) based on the principles of active inference that are integral to human natural language behavior and are thereby manifest implicitly by LLMs. These principles are similar to the actor component of control systems that achieve optimal behavior when conditions of the system's fit to the environment are known and feedforward control is best, compared to more uncertain conditions when close feedback from external criteria is needed to guide behavior optimally by the external evidence. The structured prompting of LLMs then achieves the single optimal response for both the generative creativity of the LLM response and the accuracy and control of the response through alternating, and then integrating, the contextual prompts according to these principles.

Abstract: The Neuromorphic Emulation Constructor AI (NECA) is an artificial intelligence technology for building a Personal Neuromorphic Emulation (PNE), a detailed model of an individual's brain that is anatomically correct, capable of learning and plasticity, and able to emulate the person's brain electrical activity and behavior. The NECA accesses the neuroscience literature through automated search and acquisition technologies such as Google Scholar, and it assembles the knowledge of the brain's structure and function in ways that specify how to build and test the PNE.

Abstract: A method for treating anxiety disorders may include applying a first pair of electrodes on the left side of a subject's head and a second pair of electrodes on the right side of the subject's head; applying a first stimulus carrier of a first magnitude to the first pair of electrodes and a second stimulus carrier of a second magnitude to the second pair of electrodes, wherein the first and second stimulus carriers combine to produce a stimulus having a frequency between 1 Hz and 1 kHz; and steering the stimulus toward the subject's left amygdala.

Abstract: A truncated icosahedral neural sensor net and modular elements therefor. The neural sensor net comprises a plurality of substantially pentagonally shaped elements connected to each other with elongate elastic tension lines at their respective vertices, the tension lines defining therebetween a plurality of substantially hexagonally shaped elements. The neural sensor net may be assembled from a plurality of modular elements.

Abstract: A method and system for stimulating the neurophysiology of sleep. The method and system are particularly adapted for stimulating the orbitofrontal cortex and at least one of the person's temporal lobes using transcranial electrical stimulation.

Abstract: A method for desynchronizing a pathological neural oscillations, includes identifying a first subpopulation of the neurons involved in the pathological neural oscillation that are in alignment with each other within a predetermined angular stimulation range, and a second subpopulation that are both (A) in alignment with each other within the predetermined angular stimulation range, and (B) out of alignment with the first neurons by at least the predetermined angular stimulation range, and applying electrical stimuli to the first and second subpopulations through scalp electrodes, the electrical stimuli being out of phase with the pathological neural oscillations for desynchronizing the pathological neural oscillations.

Abstract: A method for using electrical stimulation for cerebral network analysis. A first source localization procedure is performed, including a first source measurement procedure which produces first source measurement data, using the first source measurement data to find a solution to a first ill-posed problem which provides a first estimated location of the source. The body is electrically stimulated by targeting the first estimated location, and a second, fast source measurement procedure producing second source measurement data is performed thereafter while measurable effects of the step of stimulating, on the source, still remain. The second source measurement data are compared with the first source measurement data for assessing an extent to which the first estimated location is correct.

Abstract: Method for transcranial neurostimulation. A target of neurons for transcranial stimulation or modulation is located within an impedance model of the brain, a model of a selected device to be used for producing an electric or magnetic field outside the brain is obtained and used, along with the impedance model, to compute respective virtual target stimulating current vectors representing target stimulating currents that would result from using the device in two distinct trial dispositions of the device, an image of the cortical surface at the target is obtained and used to compute a target normal vector, and a determination is made of which of the two virtual target stimulating current vectors has a greater component projecting at predetermined angles from the target normal vector.

Abstract: A method and composition for probing the body through the skin. In one embodiment of the invention, the method includes providing a medium for interfacing with the skin, applying the medium to the skin at a selected location, and coupling at least two of (a) an electric signal, (b) an acoustic signal, and (c) an optical signal through the skin and through the medium at the selected location.