Patents by Inventor Phi Pham

Phi Pham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mitochondrial apoptotic sensor
    Patent number: 10718756
    Abstract: Mitochondria are central to the intrinsic apoptotic pathway of programmed cell death. Commitment to cell death occurs upon mitochondrial outer membrane permeabilization, and dysregulation of this vital apoptotic control point is implicated in various pathologies. Provided herein are novel sensors which can detect, in real time and with great sensitivity, the release of protons from intact mitochondria caused by mitochondrial outer membrane permeabilization. Embodiments include graphene based ion-sensitive field effect transistors.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: July 21, 2020
    Assignee: The Regents of the University of California
    Inventors: Peter Burke, Ted Pham, Phi Pham
  • Mitochondrial Apoptotic Sensor
    Publication number: 20180120300
    Abstract: Mitochondria are central to the intrinsic apoptotic pathway of programmed cell death. Commitment to cell death occurs upon mitochondrial outer membrane permeabilization, and dysregulation of this vital apoptotic control point is implicated in various pathologies. Provided herein are novel sensors which can detect, in real time and with great sensitivity, the release of protons from intact mitochondria caused by mitochondrial outer membrane permeabilization. Embodiments include graphene based ion-sensitive field effect transistors.
    Type: Application
    Filed: October 27, 2017
    Publication date: May 3, 2018
    Inventors: Peter Burke, Ted Pham, Phi Pham