Patents by Inventor Phil Alper

Phil Alper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and Compositions as Tpo Mimetics
    Publication number: 20080194668
    Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TPO activity, particularly diseases or disorders that involve thrombocytopenia.
    Type: Application
    Filed: August 15, 2006
    Publication date: August 14, 2008
    Applicant: IRM LLC
    Inventors: Thomas Marsilje, Wenshuo Lu, Phil Alper, Daniel Mutnick, Yun He
  • Inhibitors of cathepsin S
    Patent number: 7384970
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: June 10, 2008
    Assignee: IRM LLC
    Inventors: Hong Liu, Phil Alper, Arnab Chatterjee, David Tully, Badry Bursulaya, David Woodmansee, Robert Epple, Jennifer Leslie Harris, Jun Li
  • Inhibitors of cathepsin S
    Publication number: 20040248887
    Abstract: The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
    Type: Application
    Filed: March 23, 2004
    Publication date: December 9, 2004
    Applicant: IRM LLC
    Inventors: Hong Liu, Phil Alper, Arnab Chatterjee, David Tully, Badry Bursulaya, David Woodmansee, Robert Epple, Jennifer Leslie Harris, Jun Li
  • Nucleic acid binders having an hydroxyamine motif
    Patent number: 6120997
    Abstract: The invention relates to the combination of hydroxyamines with nucleic acid binding motifs to generate molecules and libraries of molecules targeting specific nucleic acid sequences. In particular, a series of libraries are constructed which contain hydroxyamine functionalities that are attached to various template backbones which display varying degrees of molecular recognition to phosphodiesters and varying degrees of sequence specific recognition to nucleic acids.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: September 19, 2000
    Assignee: The Scripps Research Institute
    Inventors: Chi-Huey Wong, Martin Hendrix, Phil Alper, E. Scott Priestley