Patents by Inventor Phil Lefebvre

Phil Lefebvre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ultra-sensitive detection of analytes
    Publication number: 20100035243
    Abstract: The present invention relates to screening methods, compositions, and kits for detecting for the presence or absence of one or more target analytes, e.g. biomolecules, in a sample. In particular, the present invention relates to methods that utilize nanoparticle probes in an in-solution homogeneous assay system for high-sensitivity detection of target proteins or nucleic acids based on flow analysis of single particles.
    Type: Application
    Filed: December 20, 2006
    Publication date: February 11, 2010
    Applicant: Nanosphere, Inc.
    Inventors: Uwe R. Muller, Phil Lefebvre
  • Compositions, kits, and methods for modulating survival and differentiation of multi-potential hematopoietic progenitor cells
    Patent number: 6261841
    Abstract: The invention includes compositions, kits, and methods for modulating survival and differentiation of mammalian multi-potential hematopoietic progenitor cells using a placental glycoprotein hormone of the murine prolactin family, namely either murine prolactin-like protein E or murine prolactin-like protein F. The compositions, kits, and methods described herein can be used, for example, for in vitro or ex vivo expansion of hematopoietic precursor cells or to treat a disorder associated with aberrant hematopoiesis (e.g., pre-eclampsia and thrombocytopenia).
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: July 17, 2001
    Assignee: The Board of Trustees of Northwestern University
    Inventors: Isaac Cohen, Phil Lefebvre, Jiandie Lin, Daniel Linzer