Patents by Inventor Phil Nova

Phil Nova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating APOE4/4-associated disorders
    Patent number: 12544348
    Abstract: The present disclosure provides methods of treating Alzheimer's Disease (AD) and rescuing cognitive deficits associated with AD in a subject having an apoE4/4 genotype, by administering a therapeutically effective amount of the loop-diuretic bumetanide to the subject. Also disclosed are kits for performing the method, including one or more doses of a bumetanide formulation; and which may also include instructions for treating a patient having an apoE4/4 genotype by administering bumetanide, and/or instructions and reagents for testing/identifying a subject having an apoE4/4 genotype.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 10, 2026
    Assignees: The J. David Gladstone Institutes, The Regents of the University of California
    Inventors: Yadong Huang, Alice Taubes, Phil Nova, Marina Sirota
  • METHODS FOR TREATING APOE4/4-ASSOCIATED DISORDERS
    Publication number: 20210228519
    Abstract: The present disclosure provides methods of treating Alzheimer's Disease (AD) and rescuing cognitive deficits associated with AD in a subject having an apoE4/4 genotype, by administering a therapeutically effective amount of the loop-diuretic bumetanide to the subject. Also disclosed are kits for performing the method, including one or more doses of a bumetanide formulation; and which may also include instructions for treating a patient having an apoE4/4 genotype by administering bumetanide, and/or instructions and reagents for testing/identifying a subject having an apoE4/4 genotype.
    Type: Application
    Filed: April 12, 2019
    Publication date: July 29, 2021
    Inventors: Yadong Huang, Alice Taubes, Phil Nova, Marina Sirota