Patents by Inventor Phil Skolnick

Phil Skolnick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS, DEVICES, AND METHODS FOR THE TREATMENT OF OVERDOSE AND REWARD-BASED DISORDERS
    Publication number: 20240408004
    Abstract: Drug products adapted for nasal delivery, comprising a device filled with a pharmaceutical composition comprising naltrexone are provided. Formulations and methods of treating alcohol use disorder and related conditions with the drug products are also provided.
    Type: Application
    Filed: December 21, 2023
    Publication date: December 12, 2024
    Applicants: Aegis Therapeutics, LLC, Indivior UK Limited
    Inventors: Edward T. MAGGIO, Roger CRYSTAL, Mark ELLISON, Phil SKOLNICK, Arvind AGRAWAL
  • FORMULATIONS AND METHODS FOR THE PREVENTION OF OPIOID OVERDOSE
    Publication number: 20240197719
    Abstract: Formulations and methods for the preventative treatment of incidental opioid overdose comprising the intranasal (IN) administration of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.
    Type: Application
    Filed: February 8, 2024
    Publication date: June 20, 2024
    Applicants: Aegis Therapeutics, LLC, Indivior Inc.
    Inventors: Roger CRYSTAL, Phil SKOLNICK, Edward T. MAGGIO
  • Methods, Parenteral Pharmaceutical Formulations, and Devices for the Prevention of Opioid Overdose
    Publication number: 20230225961
    Abstract: Methods, pharmaceutical formulations and devices for the preventative treatment of incidental opioid overdose comprising the intramuscular or subcutaneous administration using an auto-injection device of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.
    Type: Application
    Filed: February 27, 2023
    Publication date: July 20, 2023
    Inventors: Roger Crystal, Phil Skolnick, Edward T. Maggio
  • METHODS AND COMPOSITIONS FOR TREATING CANNABINOID OVERDOSE WITH A CANNABINOID RECEPTOR ANTAGONIST
    Publication number: 20230077724
    Abstract: Disclosed herein are formulations and methods for reversing one or more symptoms of cannabinoid overdose, comprising parenterally administering a CB1 antagonist in an amount sufficient to reverse the cannabinoid overdose symptoms.
    Type: Application
    Filed: October 14, 2022
    Publication date: March 16, 2023
    Inventor: Phil SKOLNICK
  • Compositions and Methods for the Treatment of Opioid Overdose
    Publication number: 20230055547
    Abstract: Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising nalmefene are provided. Methods of treating opioid overdose with the drug products are also provided.
    Type: Application
    Filed: August 4, 2022
    Publication date: February 23, 2023
    Inventors: Phil Skolnick, Mark Ellison, Roger Crystal
  • Compositions and methods for treating cannabinoid hyperemesis syndrome with a cannabinoid receptor antagonist
    Patent number: 11471437
    Abstract: Disclosed herein are formulations and methods for reversing one or more symptoms of cannabinoid hyperemesis syndrome (CHS) or one or more symptoms thereof, comprising parenterally administering a CB1 antagonist in an amount sufficient to reverse the CHS or symptom(s).
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: October 18, 2022
    Assignee: Opiant Pharmaceuticals, Inc.
    Inventor: Phil Skolnick
  • METHODS, PARENTERAL PHARMACEUTICAL FORMULATIONS, AND DEVICES FOR THE PREVENTION OF OPIOID OVERDOSE
    Publication number: 20210401827
    Abstract: Methods, pharmaceutical formulations and devices for the preventative treatment of incidental opioid overdose comprising the intramuscular or subcutaneous administration using an auto-injection device of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.
    Type: Application
    Filed: November 7, 2019
    Publication date: December 30, 2021
    Inventors: Roger Crystal, Phil Skolnick
  • METHODS, PARENTERAL PHARMACEUTICAL FORMULATIONS, AND DEVICES FOR THE PREVENTION OF OPIOID OVERDOSE
    Publication number: 20210275444
    Abstract: Methods, pharmaceutical formulations and devices for the preventative treatment of incidental opioid overdose comprising the intramuscular or subcutaneous administration using an auto-injection device of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.
    Type: Application
    Filed: May 13, 2021
    Publication date: September 9, 2021
    Inventors: Roger Crystal, Phil Skolnick
  • FORMULATIONS AND METHODS FOR THE PREVENTION OF OPIOID OVERDOSE
    Publication number: 20210220346
    Abstract: Formulations and methods for the preventative treatment of incidental opioid overdose comprising the intranasal (IN) administration of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.
    Type: Application
    Filed: May 15, 2019
    Publication date: July 22, 2021
    Inventors: Roger Crystal, Phil Skolnick, Edward T. Maggio
  • Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders
    Publication number: 20210023049
    Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
    Type: Application
    Filed: February 28, 2020
    Publication date: January 28, 2021
    Inventors: Phil SKOLNICK, Anthony BASILE, Zhengming CHEN, Joseph W. EPSTEIN
  • COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME WITH A CANNABINOID RECEPTOR ANTAGONIST
    Publication number: 20210015791
    Abstract: Disclosed herein are formulations and methods for reversing one or more symptoms of cannabinoid hyperemesis syndrome (CHS) or one or more symptoms thereof, comprising parenterally administering a CB1 antagonist in an amount sufficient to reverse the CHS or symptom(s).
    Type: Application
    Filed: June 17, 2020
    Publication date: January 21, 2021
    Inventor: Phil SKOLNICK
  • COMPOSITIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE WITH A CANNABINOID RECEPTOR ANTAGONIST
    Publication number: 20200397749
    Abstract: Provided are formulations and methods for treating, reversing, or reducing acute cannabinoid overdose, cannabinoid hyperemesis syndrome, or one or more symptoms thereof, comprising parenterally administering a CB1 antagonist in an amount sufficient to reverse the acute cannabinoid overdose, cannabinoid hyperemesis syndrome, or symptom(s) thereof.
    Type: Application
    Filed: June 17, 2020
    Publication date: December 24, 2020
    Inventor: Phil SKOLNICK
  • COMPOSITIONS, DEVICES, AND METHODS FOR THE TREATMENT OF OVERDOSE AND REWARD-BASED DISORDERS
    Publication number: 20200390691
    Abstract: Drug products adapted for nasal delivery, comprising a device filled with a pharmaceutical composition comprising naltrexone are provided. Formulations and methods of treating alcohol use disorder and related conditions with the drug products are also provided.
    Type: Application
    Filed: December 19, 2019
    Publication date: December 17, 2020
    Inventors: Edward T. Maggio, Roger Crystal, Mark Ellison, Phil Skolnick
  • COMPOSITIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE WITH A CANNABINOID RECEPTOR ANTAGONIST
    Publication number: 20200179271
    Abstract: Disclosed herein are formulations and methods for reversing cannabinoid overdose or one or more symptoms thereof, comprising parenterally administering a CB1 antagonist in an amount sufficient to reverse the cannabinoid overdose or symptom(s).
    Type: Application
    Filed: December 5, 2019
    Publication date: June 11, 2020
    Inventor: Phil SKOLNICK
  • Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders
    Publication number: 20190070148
    Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
    Type: Application
    Filed: July 5, 2018
    Publication date: March 7, 2019
    Inventors: Phil SKOLNICK, Anthony BASILE, Zhengming CHEN, Joseph W. EPSTEIN
  • 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
    Patent number: 10039746
    Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: August 7, 2018
    Assignee: OTSUKA AMERICA PHARMACEUTICAL, INC.
    Inventors: Phil Skolnick, Anthony Basile, Zhengming Chen, Joseph W. Epstein
  • Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders
    Publication number: 20180000777
    Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
    Type: Application
    Filed: July 12, 2017
    Publication date: January 4, 2018
    Inventors: Phil SKOLNICK, Anthony BASILE, Zhengming CHEN, Joseph W. EPSTEIN
  • 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
    Patent number: 9737506
    Abstract: The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety.
    Type: Grant
    Filed: November 1, 2015
    Date of Patent: August 22, 2017
    Assignee: NEUROVANCE, INC.
    Inventors: Phil Skolnick, Anthony Basile, Zhengming Chen, Joseph W. Epstein
  • USE OF (+)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE TO TREAT ADDICTIVE DISORDERS INCLUDING NICOTINE ADDICTION
    Publication number: 20170209415
    Abstract: The present invention relates to (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane and pharmaceutically acceptable active salts, polymorphs, glycosylated derivatives, metabolites, solvates, hydrates, and/or prodrugs of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane and their use alone or in combination with additional anti-addictive compositions in the treatment of nicotine addiction and related disorders.
    Type: Application
    Filed: September 6, 2016
    Publication date: July 27, 2017
    Inventors: Anthony Alexander McKinney, Franklin Bymaster, Phil Skolnick
  • NOVEL 1-HETEROARYL-3-AZABICYCLO[3.1.0]HEXANES, METHODS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
    Publication number: 20170204088
    Abstract: The invention provides novel 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including but not limited to depression and anxiety.
    Type: Application
    Filed: January 31, 2017
    Publication date: July 20, 2017
    Inventors: Phil Skolnick, Zhengming Chen