Patents by Inventor Philberta Leung

Philberta Leung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATION OF HYPOXIA ASSOCIATED WITH STROKE
    Publication number: 20240026399
    Abstract: The invention provides H-NOX proteins for the delivery of oxygen to hypoxic tissue following stroke. H-NOX proteins extravasate into hypoxic penumbra associated with stroke and preferentially accumulate for sustained delivery of oxygen to the hypoxic tissue to ameliorate adverse affects of stroke related hypoxia. In some embodiments, the H-NOX comprises PEGylated H-NOX and non-PEGylated H-NOX.
    Type: Application
    Filed: April 27, 2023
    Publication date: January 25, 2024
    Inventors: Natacha LE MOAN, Ana KRTOLICA, Philberta LEUNG, Stephen P.L. CARY
  • MODULATION OF HYPOXIA ASSOCIATED WITH STROKE
    Publication number: 20210121521
    Abstract: The invention provides H-NOX proteins for the delivery of oxygen to hypoxic tissue following stroke. H-NOX proteins extravasate into hypoxic penumbra associated with stroke and preferentially accumulate for sustained delivery of oxygen to the hypoxic tissue to ameliorate adverse affects of stroke related hypoxia. In some embodiments, the H-NOX comprises PEGylated H-NOX and non-PEGylated H-NOX.
    Type: Application
    Filed: December 23, 2020
    Publication date: April 29, 2021
    Applicant: Omniox, Inc.
    Inventors: Natacha Le Moan, Ana Krtolica, Philberta Leung, Stephen P. L. Cary
  • MODULATION HYPOXIA ASSOCIATED WITH STROKE
    Publication number: 20200276265
    Abstract: The invention provides H—NOX proteins for the delivery of oxygen to hypoxic tissue following stroke. H—NOX proteins extravasate into hypoxic penumbra associated with stroke and preferentially accumulate for sustained delivery of oxygen to the hypoxic tissue to ameliorate adverse affects of stroke related hypoxia. In some embodiments, the H—NOX comprises PEGylated H—NOX and non-PEGylated H—NOX.
    Type: Application
    Filed: February 16, 2017
    Publication date: September 3, 2020
    Applicant: Omniox, Inc.
    Inventors: Natacha Le Moan, Ana Krtolica, Philberta Leung, Stephen P.L. Cary
  • Antibodies capable of binding to the coagulation Factor XI and/or its activated form factor Xia and uses thereof
    Patent number: 9783614
    Abstract: The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: October 10, 2017
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Andreas Wilmen, Julia Straβburger, Frank Dittmer, Michael Strerath, Anja Buchmüller, Joanna Grudzinska-Goebel, Ricarda Finnern, Martina Schäfer, Christoph Gerdes, Hannah Jöriβen, Asako Itakura, Philberta Leung, Erik Tucker
  • Antibodies against factor XII and uses thereof
    Patent number: 9574013
    Abstract: Provided are antibodies that selectively bind to and inhibit activation of coagulation factor XII. Methods of treatment employing these antibodies are described herein.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: February 21, 2017
    Assignees: VANDERBILT UNIVERSITY, ARONORA, INC., OREGON HEALTH & SCIENCE UNIVERSITY
    Inventors: Andras Gruber, David Gailani, Philberta Leung, Anton Matafonov
  • ANTIBODIES AGAINST FACTOR XII AND USES THEREOF
    Publication number: 20150315292
    Abstract: Provided are antibodies that selectively bind to and inhibit activation of coagulation factor XII. Methods of treatment employing these antibodies are described herein.
    Type: Application
    Filed: December 6, 2013
    Publication date: November 5, 2015
    Inventors: Andras GRUBER, David GAILANI, Philberta LEUNG, Anton MATAFONOV
  • Antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and uses thereof
    Publication number: 20150099298
    Abstract: The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.
    Type: Application
    Filed: May 8, 2013
    Publication date: April 9, 2015
    Inventors: Andreas Wilmen, Julia Straßburger, Frank Dittmer, Michael Strerath, Anja Buchmüller, Joanna Grudzinska-Goebel, Ricarda Finnern, Martina Schäfer, Christoph Gerdes, Hannah Jörißen, Asako Itakura, Philberta Leung, Erik Tucker