Patents by Inventor Philip A. Gale

Philip A. Gale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calixpyrroles
    Patent number: 7122572
    Abstract: The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: October 17, 2006
    Assignee: Board of Regents, University of Texas System
    Inventors: Philip A. Gale, Jonathan L. Sessler, Vladimír A. Král, Andrei Andrievsky, Vincent Lynch, Petra I. Sansom, William E. Allen, Christopher T. Brown, Andreas Gebauer
  • Calixpyrroles, calixpyridinopyrroles, and calixpyridines
    Publication number: 20020026047
    Abstract: The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives. conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.
    Type: Application
    Filed: April 20, 2001
    Publication date: February 28, 2002
    Inventors: Philip A. Gale, Jonathan L. Sessler, John W. Genge, Vladimir A. Kral, Andrei Andrievsky, Vincent Lynch, Petra I. Sansom, William E. Allen, Christopher T. Brown, Andreas Gebauer
  • Calixpyrroles, calixpyridinopyrroles and calixpyridines
    Patent number: 6262257
    Abstract: The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: July 17, 2001
    Assignee: Board of Regents, University of Texas System
    Inventors: Philip A. Gale, Jonathan L. Sessler, John W. Genge, Vladimír A. Král, Andrei Andrievsky, Vincent Lynch, Petra I. Sansom, William E. Allen, Christopher T. Brown, Andreas Gebauer