Patents by Inventor Philip A. Lee

Philip A. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170009250
    Abstract: The present disclosure relates to methods of expressing therapeutic proteins in photosynthetic organisms and the therapeutic proteins produced by the methods. The therapeutic proteins include high-mobility group box 1 (HMGB1) protein, fibronectin domain (10) (10FN3), fibronectin domain (14) (14FN3), interferon beta (IFN?), proinsulin and vascular endothelial growth factor (VEGF). The photosynthetic organisms include prokaryotes such as cyanobacteria and eukaryotes such as alga and plants. Transformation of eukaryotes is preferably the plastid genome, more preferably the chloroplast genome.
    Type: Application
    Filed: January 28, 2016
    Publication date: January 12, 2017
    Applicants: Sapphire Energy, Inc., The Scripps Research Institute
    Inventors: Beth A. Rasala, Rosa M. F. Cardoso, Machiko Muto, Stephen P. Mayfield, Philip A. Lee, Craig A. Behnke, Michael Mendez
  • Publication number: 20150059023
    Abstract: The present disclosure provides several novel genes that have been shown to increase the biomass yield or biomass of a photosynthetic organism. The disclosure also provides methods of using the novel genes and organisms transformed with the novel genes.
    Type: Application
    Filed: February 14, 2013
    Publication date: February 26, 2015
    Applicant: Sapphire Energy, Inc.
    Inventors: Christopher Yohn, Philip A. Lee
  • Publication number: 20120309939
    Abstract: The present disclosure relates to methods of expressing therapeutic proteins in photosynthetic organisms and the therapeutic proteins produced by the methods. The therapeutic proteins include high-mobility group box 1 (HMGB1) protein, fibronectin domain (10) (10FN3), fibronectin domain (14) (14FN3), interferon beta (IFN?), proinsulin and vascular endothelial growth factor (VEGF). The photosynthetic organisms include prokaryotes such as cyanobacteria and eukaryotes such as alga and plants. Transformation of eukaryotes is preferably the plastid genome, more preferably the chloroplast genome.
    Type: Application
    Filed: November 19, 2010
    Publication date: December 6, 2012
    Applicants: THE SCRIPPS RESEARCH INSTITUTE, SAPPHIRE ENERGY, INC.
    Inventors: Beth A. Rasala, Rosa M. F. Cardoso, Machiko Muto, Stephen P. Mayfield, Philip A. Lee, Craig A. Behnke, Michael Mendez
  • Publication number: 20080250327
    Abstract: A code is included in content, which code allows a user to use a comment tool to select some or all of the content, to create and submit comments, and to view previously submitted content selections and comments in conjunction with additional content. The additional content may comprise advertisements.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 9, 2008
    Applicant: Microsoft Corporation
    Inventors: Ying Li, Tarek Najm, Philip A. Lee
  • Patent number: 7174099
    Abstract: Systems and methods for regulating optical power are described. A system for regulating optical power includes a laser driver circuit that receives an enable/disable signal and a data modulator input. The enable/disable signal regulates asynchronous mode operation. The system also includes a laser module including a laser diode emitter and a photodiode detector. The laser module is coupled to the laser driver circuit and receives a laser bias current from the laser driver circuit. The system also includes a switch coupled to the photodiode to receive a signal from the photodiode detector. The system also includes an automatic power control (APC) feedback circuit that receives a signal from the switch and provides a laser bias current feedback signal to the laser driver circuit to compensate for power output changes in the laser diode emitter over time.
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: February 6, 2007
    Assignee: Network Appliance, Inc.
    Inventors: Stephen R. Chinn, Philip A. Lee, James K. Roberge