Patents by Inventor Philip Amuso

Philip Amuso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8815502
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: August 26, 2014
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8785176
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: July 22, 2014
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • EARLY DETECTION OF PATHOGENS IN BLOOD
    Publication number: 20120034614
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Application
    Filed: August 11, 2011
    Publication date: February 9, 2012
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: MATT EWERT, Philip Amuso, Andrew Cannons
  • Early detection of pathogens in blood
    Patent number: 7998699
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: August 16, 2011
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • Early detection of pathogens in blood
    Patent number: 7993870
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: August 9, 2011
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • Early Detection of Pathogens in Blood
    Publication number: 20090305383
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Application
    Filed: April 1, 2009
    Publication date: December 10, 2009
    Applicant: University of South Florida
    Inventors: MATT EWERT, Philip Amuso, Andrew Cannons
  • Early Detection of Pathogens in Blood
    Publication number: 20050014128
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Application
    Filed: August 15, 2003
    Publication date: January 20, 2005
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons